Molecular Biology of Membrane Transport Disorders / Edition 1

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''The scope and depth of this book are excellent....[with] in-depth reviews that will be of benefit to both novice and expert alike....An excellent text worthy of a place on any self-respecting membranologists book shelf and I recommend it highly.'' —- Trends in Biochemical Sciences Molecular Biology of Membrane Transport Disorders comprises the first compilation of papers on the important membrane transporters and ion channels with an emphasis on membrane transport disorders. Internationally recognized leaders in the field provide a thorough understanding of the pathogenesis of clinical conditions that involve derangements in membrane transport processes at the molecular level. This work is a valuable resource for medical and graduate students and researchers in the biomedical sciences, as well as academic physicians in cardiology, nephrology, neurology, and gastroenterology.

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Editorial Reviews

The six authors gathered to plan for what was to be the third edition of Physiology of Membrane Disorders and decided instead to publish the logical extension of the work (second edition, 1986) under a new title, with a new emphasis, to reflect the radical advances in the field. Structure and purpose are essentially unchanged, but because of length limitations, the present volume focuses on areas where understanding has advanced to the molecular level; sections of the second edition that were not outdated have not been duplicated. Annotation c. Book News, Inc., Portland, OR (
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Product Details

  • ISBN-13: 9780306451645
  • Publisher: Springer US
  • Publication date: 6/30/1996
  • Series: The Language of Science Series
  • Edition description: 1996
  • Edition number: 1
  • Pages: 657

Table of Contents

Biomembranes and Strategies for Study: Membrane Traffic and Compartmentalization within the Secretory Pathway (J. LippincottSchwartz). Cell Adhesion (J. Covault). The Membraneassociated Cytoskeleton and Exoskeleton (R.J. Bloch). Isolation and Reconstitution of Transporters (W.P. Dubinsky). Permeability and Conductance in Ion Channels (D.C. Dawson). Membrane Channels and Carriers: The Lactose Permease of Escherichia coli: An Update (H.R. Kaback). Structure and Function of Voltagegated Ion Channels (W.A. Catterall). Nicotinic Receptors in the Central Nervous System (C.K. Ifune, J.H. Steinbach). GABA, Glycine and Glutamategated Channels in Neurological and Psychiatric Illness (M.G. Darlison, R.J. Harvey). The Genetic and Physiological Basis of Malignant Hyperthermia (D.H. MacLennan et al.). Stretchactivated Ion Channels (H. Sackin). Cation Transport ATPases (D.M. Fambrough, G. Inesi). Multidrug Resistance Transporter (M.M. Gottesman et al.). Transport in Organized Systems: Mihondrial Transport Processes (R.S. Kaplan). Receptormediated Endocytosis (V.P. Knutson et al.). Signal Transduction by G Protein Coupled Receptors (M. Birnbaumer, L. Birnbaumer). Egg Membranes During Fertilization (L.A. Jaffe). Cell Volume Regulation (J.R. Sachs). Regulation of Cell pH (O.W. Moe, R.J. Alpern). Regulation of Intracellular Free Calcium (W.B. Busa). Sodium Transport by Epithelial Cells (L.G. Palmer). Clinical Disorders of Membrane Transport: Cell Death (T.J. Burke). Genetic Variants of Erythrocytes (J.C. Parker). Disorders of Biliary Secretion (P. Zimniak, R. Lester). The Pathophysiology of Diarrhea (J.H. Sellin). the Myasthenic Syndromes (H.J. Kaminski, R.L. Ruff). Genesis of Cardiac Arrhythmias: Roles of Calcium and Delayed Potassium Channels in the Heart (R.S. Kass). Cystic Fibrosis (M.J. Welsh). Familial Periodic Paralysis (L. Ptacek, R.C. Griggs). 4 additionalarticles. Index.

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