Molecular Carcinogenesis and the Molecular Biology of Human Cancer

by David Warshawsky (Editor), Joseph R. Landolph Jr. (Editor)

Overview

For graduate students, Warshawsky (environmental health, U. of Cincinnati College of Medicine) and Landolph (molecular microbiology and immunology, pathology, and molecular pharmacology and toxicology, U. of Southern California) offer 24 chapters on the technical and historical aspects of the science of cancer. The first section details pathology, epidemiology, stress responses, DNA methylation, oncogenes, tumor suppressor genes, DNA repair, chemical mutation, and chemical, viral, and radiation carcinogenesis. The second part focuses on breast, thyroid, skin, brain, prostate, lung, bladder, and colon cancer, leukemia, immunology and immunotherapy, and gene therapy. Contributors are researchers and practitioners from the US. Annotation © 2006 Book News, Inc., Portland, OR

Product Details

ISBN-13:	9780203503430
Publisher:	CRC Press
Publication date:	10/31/2005
Sold by:	Barnes & Noble
Format:	eBook
Pages:	592
File size:	10 MB

About the Author

Warshawsky, David; Landolph Jr., Joseph R.

Table of Contents

Carcinogens and Mutagens: David Warshawsky
Whole Animal Carcinogenicity Bioassays: Joseph R. Landolph, Jr., Weiling Xue, and David Warshawsky
Molecular Mechanisms of Action of Selected Organic Carcinogens: Weiling Xue and David Warshawsky
Binding of Carcinogens to DNA and Covalent Adducts and DNA Damage- PAH, Aromatic Amines, Nitro-aromatic Compounds, and Halogenated Compounds: Jeffrey Ross
Cellular Oncogenes and Carcinogenesis: Helmut Zarbl
Tumor Suppressor Genes: Bernard E. Weissman
Hepatitis B, Hepatitis C, and Hepatocellular Carcinoma: Jing-hsiung Ou
Oncongenesis in Transgenic and Knockout Mice: Laura Erker and Anthony Wynshaw-Boris
Chemically Induced Morphological and Neoplastic Transformation in C3H/10T1/2 Cl 8 Mouse Embryo Cells: Joseph R. Landolph Jr.
Radiation Carcinogenesis: Colin K. Hill and Donna M. Williams-Hill
DNA Microarrays and Computational Analysis of DNA Microarray Data in Cancer Research: Mario Medvedovic and Jonathan S. Wiest
Application of Proteomics in Basic Biological Sciences and Cancer: Christoph Borchers, Ting Chen, and Nouri Neamati
Overview of Human Cancer Induction and Human Exposure to Carcinogens: David Warshawsky and Joseph R. Landolph Jr.
Complex Mixtures of Chemical Carcinogens: Principles of Action and Human Cancer: Stephen Nesnow
Lung Cancer: Jay W. Tichelaar and George D. Leikauf
Breast Cancer: Sue C. Heffelfinger
Cancer of the Prostate- Mechanisms of Molecular Carcinogenesis: Daniel Djakiew
Skin Cancer: Epidemiology, Clinical Manifestations, and Genetic and Molecular Aspects: Zalfa A. Abdel-Malek, Ana Luisa Kadekaro, Michelle A. Pipitone, and Diya F. Mutasim
Cell and Molecular Biology of Cancer of the Brain: Ole Didrik Laerum
Thyroid Cancer: Molecular Biology and Clinical Aspects: Johan R. Lillehaug, Øystein Fluge, and Jan Erik Varhaug
Chemoprevention of Chemical Carcinogenesis and Human Cancer: Mark A. Morse and Gary D. Stoner
Carcinogen Biomarkers and Exposure Assessment: Glenn Talaska
Risk Assessment for Chemical Carcinogens: Andrew G. Salmon
Chapter 24 Prevention and Regulation Approaches to Carcinogens: Eula Bingham and Jon Reid
Index