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Molecular Cardiology for the Cardiologist
     

Molecular Cardiology for the Cardiologist

by Bernard Swynghedauw
 

Molecular Cardiology for the Cardiologist, Second Edition provides a short, easily readable summary of what the new biology brings to cardiology. Special efforts have been made to include comprehensive diagrams and drawings, as well as teaching tables, and also to keep the size of the second edition within the modest limits of the first edition.
The book

Overview

Molecular Cardiology for the Cardiologist, Second Edition provides a short, easily readable summary of what the new biology brings to cardiology. Special efforts have been made to include comprehensive diagrams and drawings, as well as teaching tables, and also to keep the size of the second edition within the modest limits of the first edition.
The book remains divided into 5 parts. The first part is a general introduction to the new terminology. The second part is devoted to the normal structure of the heart and vessels. Parts 3 and 4 deal with physiopathology. One of the important contributions of molecular biology to cardiology is a better understanding of the general process of adaptation of the heart and vessels to a permanent mechanical overloading. Such a process is generally called remodeling, and results from coordinate changes in the expression of the genes. The last part of the book includes information on gene and cellular therapy.

Editorial Reviews

3 Stars from Doody
John F. Moran
This text deals with the new language of biology, molecular structure, physiology of the normal heart, cardiac and vascular remodeling, genetics for the non-geneticist, gene therapy, and cell transplantation. The purpose is to make available a short, well-written summary of what cellular molecular biology brings to cardiology. It is an important objective since many cardiologists are trained in anatomy and physiology. The book is well written. It is intended for clinicians and primary care physicians and deals with the knowledge explosion in the cellular molecular cardiac area in the past five years or so. The book begins with definitions from mitosis and cell division to the genetic code in the Human Genome Project. The basic tools of molecular biology such as probes and oligonucleotides, restriction enzymes, and the polymerase chain reaction are described. There are many excellent tables listing membrane protein families as well as ion channels and other important areas. The text is well illustrated with black-and-white drawings so the reader can follow the text with the help of the illustrations. There is a discussion of the genetics of hyperlipidemia and a brief discussion of the use of gene therapy. An important section is a glossary of terms. This second edition is certainly worthwhile in an area that is showing such rapid development. The text represents an opportunity for clinical cardiologists to drill down to the cellular molecular area where their previous experience in education has been based on anatomy and hemodynamics. It is a worthwhile addition to the cardiac literature.
Elias G. Eleftheriadis
This new book attempts to bridge the gap between basic science and clinical cardiology. It contains an introduction to basic molecular biology concepts and a glossary of the newly introduced words in the clinician's vocabulary. New molecular biology techniques currently in use in basic research and clinical practice are also described. The purpose is to provide an introduction to the rapidly growing field of molecular cardiology and a comprehensive approach to the new applications of the new biology in the diagnosis and possible treatment of cardiovascular diseases. Although there are other published books with the same objectives, the size of this book makes it particularly appealing to the interested reader. This publication meets the author's objectives to present the relation of cardiology and molecular biology in a concise way without compromising the content. The audience includes medical students, residents in internal medicine, and fellows in cardiovascular diseases. The interested practicing cardiovascular diseases specialist and the general practitioner will be greatly benefit in following the current scientific literature and the new developments in understanding diagnosing and treating cardiovascular diseases. This book's 250 pages are divided into 5 parts. The figures make the text easier to read and understand. A comprehensive glossary might also be considered as a vital part of the book. This is a very well written and easy to understand book covering the new insights that molecular biology provided in the understanding of the physiology and pathophysiology of the cardiovascular diseases. This book should be easily accessible as a quick and reliable reference to allinterested cardiologists.
Booknews
For practicing and student cardiologists, explains what the new biology of the past couple of decades has brought to the field. Introduces the new language, the syntax of relationships as well as the terminology. Presents the new view of the normal structure of the heart and vessels; diseases of adaptation, including the hypertrophied and senescent heart; genetics, including DNA polymorphism and inherited diseases; and gene transfers and therapy. The translation is fairly stilted but comprehensible. Includes a glossary without pronunciation. Double spaced. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Doody's Review Service
Reviewer: John F. Moran, MD (Loyola University Stritch School of Medicine)
Description: This text deals with the new language of biology, molecular structure, physiology of the normal heart, cardiac and vascular remodeling, genetics for the non-geneticist, gene therapy, and cell transplantation.
Purpose: The purpose is to make available a short, well-written summary of what cellular molecular biology brings to cardiology. It is an important objective since many cardiologists are trained in anatomy and physiology. The book is well written.
Audience: It is intended for clinicians and primary care physicians and deals with the knowledge explosion in the cellular molecular cardiac area in the past five years or so.
Features: The book begins with definitions from mitosis and cell division to the genetic code in the Human Genome Project. The basic tools of molecular biology such as probes and oligonucleotides, restriction enzymes, and the polymerase chain reaction are described. There are many excellent tables listing membrane protein families as well as ion channels and other important areas. The text is well illustrated with black-and-white drawings so the reader can follow the text with the help of the illustrations. There is a discussion of the genetics of hyperlipidemia and a brief discussion of the use of gene therapy. An important section is a glossary of terms.
Assessment: This second edition is certainly worthwhile in an area that is showing such rapid development. The text represents an opportunity for clinical cardiologists to drill down to the cellular molecular area where their previous experience in education has been based on anatomy and hemodynamics. It is a worthwhile addition to the cardiac literature.

Product Details

ISBN-13:
9781461372554
Publisher:
Springer US
Publication date:
04/30/2013
Series:
Developments in Cardiovascular Medicine Series , #208
Edition description:
Softcover reprint of the original 2nd ed. 1998
Pages:
301
Product dimensions:
6.10(w) x 9.25(h) x 0.03(d)

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