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Molecular Diagnostics for Melanoma: Methods and Protocols
     

Molecular Diagnostics for Melanoma: Methods and Protocols

by Magdalena Thurin (Editor), Francesco M. Marincola (Editor)
 

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In Molecular Diagnostics for Melanoma: Methods and Prools, expert researchers and clinicians in the field of melanoma provide updated information on biomarkers and assays for diagnosis, prognosis, and assays predicting response to treatment for routine testing. The focus of the volume is on biomarkers with established clinical validity rather than those

Overview

In Molecular Diagnostics for Melanoma: Methods and Prools, expert researchers and clinicians in the field of melanoma provide updated information on biomarkers and assays for diagnosis, prognosis, and assays predicting response to treatment for routine testing. The focus of the volume is on biomarkers with established clinical validity rather than those on early discovery stage.With additional in-depth discussion of the molecular biology and pathology of melanoma, treatment options in adjuvant and metastatic setting, and implications of biomarker testing for clinical management of melanoma patients.

Written in the highly successful Methods in Molecular Biology series format, chapters include extensive introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory prools, and key tips on troubleshooting and avoiding known pitfalls.

Comprehensive and practical, Molecular Diagnostics for Melanoma: Methods and Prools seeks to provide both clinicians and scientists with technical information and extensive background information on the wide ranging approaches available in the field of diagnostics of melanoma.

Editorial Reviews

Doody's Review Service
Reviewer: Valerie L. Ng, PhD MD(Alameda County Medical Center/Highland Hospital)
Description: This substantive book is a compilation of focused reviews and laboratory protocols for biomarkers associated with melanoma and related targeted therapies.
Purpose: The purpose is to "provide updated information on well-characterized diagnostic and prognostic assays and assays predicting response to treatment for routine testing." These are worthy objectives in this rapidly evolving area, well met by this book.
Audience: This would be useful to anyone interested in melanoma, from clinicians wanting an update on promising molecular targets for melanoma treatment to researchers wanting detailed protocols for diagnostic or treatment monitoring assays. The authors are quite credible authorities in their fields.
Features: This somewhat hefty (712 pages) book covers the breadth and depth of melanoma in 37 chapters comprising seven sections. It starts with a succinct review of clinical challenges and the current treatment of melanoma. Subsequent sections cover various biomarkers useful for estimating response to treatment, classification, diagnosis, and prognosis. An entire section is devoted to uveal melanoma. The last three sections discuss emerging markers or targets, technologies for marker validation, and (most important in my opinion) validation requirements for clinical application. True to the nature of Springer Protocols, this book is full of detailed laboratory protocols, easy to follow and ready to implement. Many are accompanied by exemplary photographs of the expected results. As an example of the considerable detail, the preface alone is nine pages and written in conventional scientific style, including an abstract(!).
Assessment: If you are working in melanoma research or treating patients with melanoma, you will very much appreciate this book.

Product Details

ISBN-13:
9781627037266
Publisher:
Springer-Verlag New York, LLC
Publication date:
12/31/2013
Series:
Methods in Molecular Biology Series , #1102
Edition description:
2014
Pages:
712
Product dimensions:
7.01(w) x 10.00(h) x 0.06(d)

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