Molecular Endocrinology of Cancer, Volume 1: Part 2, Endocrine Therapies / Edition 1

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Overview

One third of human cancers have a hormonal basis. Breast cancer, the most common cancer of women, is increasing in many countries, as is prostate cancer, the second most common cancer of men. Concurrently, molecular biology has refined the definition of hormones to include the interaction between tumor cells and both locally and distantly secreted factors. This volume in the series Cancer: Clinical Science in Practice considers aspects of hormonal cancer, including the molecular basis for the autocrine and paracrine regulation of cancer, molecular strategies for cancer detection, strategies in limiting the epidemic of hormonally related cancers, and new treatment approaches.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Ann Traynor, MD (Northwestern University Feinberg School of Medicine)
Description: This is the first edition of a review book that focuses on four aspects of the endocrinology of cancer: cancer growth regulation, the treatment of endocrine-dependent cancers, prevention of endocrine dependent tumors, and endocrine complications of cancer treatment.
Purpose: The series, Cancer: Clinical Science in Practice, is meant to contribute to the understanding and management of cancer by researchers and clinicians.
Audience: Its intended audience is clinicians and researchers with an interest in the application of biomedical science to cancer. This would presumably include medical fellows, postdoctoral students and graduate students in this field, and researchers and clinical oncologists. The authors are authoritative in the areas on which they have written.
Features: The book may be underillustrated. To present molecular endocrinology of varied endocrine systems to a broad audience is challenging because any one system will not be highly familiar to the majority of the readers. Generous use of diagrams is usually beneficial. The print is clear and the size of the book is appealing. The table of contents accurately reflects the discrete areas of focus entailed in the book, allowing a peruser to determine the chapter(s) of interest. It is less likely that most users would find most of the book of interest.
Assessment: The concept of a periodic review of progress in the molecular endocrinology of cancer is a good one and probably has a real market. Many of the aspects presented in this review are neither highly contemporary and scientific nor highly comprehensive and practical as an overview for the clinician, so they are less likely to find either a broad research following or broad clinical following. A yearly or quarterly review devoted to each endocrine system and its relation to cancer might find a greater following, particularly if an individual could order the reviews by volume.
Ann Traynor
This is the first edition of a review book that focuses on four aspects of the endocrinology of cancer: cancer growth regulation, the treatment of endocrine-dependent cancers, prevention of endocrine dependent tumors, and endocrine complications of cancer treatment. The series, Cancer: Clinical Science in Practice, is meant to contribute to the understanding and management of cancer by researchers and clinicians. Its intended audience is clinicians and researchers with an interest in the application of biomedical science to cancer. This would presumably include medical fellows, postdoctoral students and graduate students in this field, and researchers and clinical oncologists. The authors are authoritative in the areas on which they have written. The book may be underillustrated. To present molecular endocrinology of varied endocrine systems to a broad audience is challenging because any one system will not be highly familiar to the majority of the readers. Generous use of diagrams is usually beneficial. The print is clear and the size of the book is appealing. The table of contents accurately reflects the discrete areas of focus entailed in the book, allowing a peruser to determine the chapter(s) of interest. It is less likely that most users would find most of the book of interest. The concept of a periodic review of progress in the molecular endocrinology of cancer is a good one and probably has a real market. Many of the aspects presented in this review are neither highly contemporary and scientific nor highly comprehensive and practical as an overview for the clinician, so they are less likely to find either a broad research following or broad clinical following. A yearlyor quarterly review devoted to each endocrine system and its relation to cancer might find a greater following, particularly if an individual could order the reviews by volume.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780521460675
  • Publisher: Cambridge University Press
  • Publication date: 4/28/2012
  • Series: Cancer: Clinical Science in Practice Series
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 440
  • Product dimensions: 5.98 (w) x 8.98 (h) x 1.14 (d)

Table of Contents

Contributor list; Part I. The Regulation of Cancer: 1. The type 1 growth factor receptor family, their ligands and their role in human cancers T. Rajkumar and W. J. Gullick; 2. The fibroblast growth factor family and their receptors Pita Enriquez Harris and John K. Heath; 3. The biological role of transforming growth factor beta in cancer development Bradley A. Arrick and Rik Derynck; 4. Bombesin and its receptor Michael J. Seckl and Enrique Rozengurt; 5. Gonadotrophin-releasing hormone and its receptor Karin A. Eidne and Lorraine Anderson; 6. Cytokines T. Hamblin; Part II. The Prevention of Endocrine-Dependent Tumours: 7. Familial Cancer Audrey D. Goddard and Donald M. Black; 8. Diet Peter Boyle and Patrick Maisonneuve; 9. Breast cancer: new biological approaches to treatment Robert B. Dickson and Robert Clarke; 10. The biological basis for the treatment of prostate cancer Jonathan Waxman, Andrew Stubbs and Hardev Pandha; 11. Carcinoid tumours S. Bloom and P. Hammond; Part III. Endocrine Complications of Cancer Treatment: 12. Humoral hypercalcaemia John J. Wysolmerski and Arthur E. Braodus; 13. Anaemia of cancer Carole B. Miller and Jerry L. Spivak; Index.

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