Molecular Genetics of Bacteria / Edition 2

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Overview

The Fourth Edition of this highly successful book provides an essential introduction to the molecular genetics of bacteria. Thoroughly revised and updated, Molecular Genetics of Bacteria now includes a much greater coverage of genomics, microarrays and proteomics. The text includes an enhanced treatment of the ways in which both classical and modern genetics have contributed to our understanding of how bacteria work. The focus of the book remains firmly on bacteria and will be invaluable to those students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.

"...thoroughly updated with new coverage of such topics as the concept of adaptive mutation,bacterial differentiation, intercellular signalling,conjugative transposons,and integ- rons...enhanced coverage of supercoining, PCR, and more."

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Editorial Reviews

Booknews
The coverage is restricted to bacterial genetics to provide a less daunting introduction for students who don't intend to pursue a career in genetics, but the material assumes a working knowledge of molecular biology. Details essential principles of nucleic acid structure and function, methods and terminology, regulation of gene expression, and extrachromosomal inheritance, and discusses recent developments in applied in vivo and in vitro genetics. Includes b&w diagrams, a glossary, and descriptions of enzymes and genes. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Doody's Review Service
Reviewer: Rebecca T. Horvat, PhD, D (ABMM)(University of Kansas Medical Center)
Description: This textbook teaches upper-level bacterial genetics at the college and graduate level, starting with the basics of molecular structure and building to the mapping of bacterial genomes..
Purpose: The purpose of this sixth edition is to provide an update of the field. In the six years since the previous edition, there has been an extraordinary increase in both the information on bacterial genetics and the techniques used to study them.
Audience: Higher-level students studying bacterial genetics are the intended audience.
Features: The book starts with basic principles of DNA structure, including the various forms DNA takes. It then presents the basic information on hybridization and transcription as well as translation. The explanation of gene organization includes how start and stop codons influence expression and how changes can influence tertiary structure. This is the foundation for the rest of the book, which covers such topics as genetic evolution that relies on variability in the genetic replication, the mechanisms that allow mutations to occur, and how bacterial genes are transferred to other bacterial strains. Later chapters cover new developments and techniques that have contributed to new information such as expression plasmids and specific mutagenesis to examine function. Additional chapters discuss comparative genomics and the analysis of gene expression. The book also demonstrates the relationship of growth in the knowledge of bacterial genomics to other fields such as biotechnology and bioengineering.
Assessment: This update of a popular textbook provides the latest information and techniques used to study bacterial genetics. It provides descriptive information, experimental methods, and clear descriptions of bacterial molecular genetics.
From the Publisher
"This update of a popular textbook provides the latest information and techniques used to study bacterial genetics. It provides descriptive information, experimental methods, and clear descriptions of bacterial molecular genetics." (Doody's, 19 August 2011)
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Product Details

  • ISBN-13: 9780471951117
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 2/7/1995
  • Edition description: Older Edition
  • Edition number: 2
  • Pages: 302
  • Product dimensions: 6.03 (w) x 9.00 (h) x 0.74 (d)

Table of Contents

1 Nucleic Acid Structure and Function 1
2 Mutation and Variation 37
3 Regulation of Gene Expression 67
4 Genetics of Bacteriophages 103
5 Plasmids 137
6 Gene Transfer 165
7 Genomic Plasticity: Movable Genes and Phase Variation 189
8 Genetic Modification: Exploiting the Potential of Bacteria 215
9 Genetic Methods for Investigating Bacteria 245
10 Gene Mapping to Genomics 273
App. A: Further Reading 301
App. B: Abbreviations 305
App. C: Glossary 309
App. D: Enzymes 323
App. E: Genes 327
App. F: Standard Genetic Code 331
App. G: Bacterial Species 333
Index 337
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