Molecular Genetics of Bacteria / Edition 4

Hardcover (Print)
Not Available on


The Fourth Edition of this highly successful book provides an essential introduction to the molecular genetics of bacteria. Thoroughly revised and updated, Molecular Genetics of Bacteria now includes a much greater coverage of genomics, microarrays and proteomics. The text includes an enhanced treatment of the ways in which both classical and modern genetics have contributed to our understanding of how bacteria work. The focus of the book remains firmly on bacteria and will be invaluable to those students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.

"...thoroughly updated with new coverage of such topics as the concept of adaptive mutation,bacterial differentiation, intercellular signalling,conjugative transposons,and integ- rons...enhanced coverage of supercoining, PCR, and more."

Read More Show Less

Editorial Reviews

The coverage is restricted to bacterial genetics to provide a less daunting introduction for students who don't intend to pursue a career in genetics, but the material assumes a working knowledge of molecular biology. Details essential principles of nucleic acid structure and function, methods and terminology, regulation of gene expression, and extrachromosomal inheritance, and discusses recent developments in applied in vivo and in vitro genetics. Includes b&w diagrams, a glossary, and descriptions of enzymes and genes. Annotation c. Book News, Inc., Portland, OR (
Doody's Review Service
Reviewer: Rebecca T. Horvat, PhD, D (ABMM)(University of Kansas Medical Center)
Description: This textbook teaches upper-level bacterial genetics at the college and graduate level, starting with the basics of molecular structure and building to the mapping of bacterial genomes..
Purpose: The purpose of this sixth edition is to provide an update of the field. In the six years since the previous edition, there has been an extraordinary increase in both the information on bacterial genetics and the techniques used to study them.
Audience: Higher-level students studying bacterial genetics are the intended audience.
Features: The book starts with basic principles of DNA structure, including the various forms DNA takes. It then presents the basic information on hybridization and transcription as well as translation. The explanation of gene organization includes how start and stop codons influence expression and how changes can influence tertiary structure. This is the foundation for the rest of the book, which covers such topics as genetic evolution that relies on variability in the genetic replication, the mechanisms that allow mutations to occur, and how bacterial genes are transferred to other bacterial strains. Later chapters cover new developments and techniques that have contributed to new information such as expression plasmids and specific mutagenesis to examine function. Additional chapters discuss comparative genomics and the analysis of gene expression. The book also demonstrates the relationship of growth in the knowledge of bacterial genomics to other fields such as biotechnology and bioengineering.
Assessment: This update of a popular textbook provides the latest information and techniques used to study bacterial genetics. It provides descriptive information, experimental methods, and clear descriptions of bacterial molecular genetics.
From the Publisher
"This update of a popular textbook provides the latest information and techniques used to study bacterial genetics. It provides descriptive information, experimental methods, and clear descriptions of bacterial molecular genetics." (Doody's, 19 August 2011)
Read More Show Less

Product Details

  • ISBN-13: 9780470850848
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 3/19/2004
  • Edition description: REV
  • Edition number: 4
  • Pages: 358
  • Product dimensions: 6.52 (w) x 9.92 (h) x 0.95 (d)

Table of Contents

1 Nucleic Acid Structure and Function 1
2 Mutation and Variation 37
3 Regulation of Gene Expression 67
4 Genetics of Bacteriophages 103
5 Plasmids 137
6 Gene Transfer 165
7 Genomic Plasticity: Movable Genes and Phase Variation 189
8 Genetic Modification: Exploiting the Potential of Bacteria 215
9 Genetic Methods for Investigating Bacteria 245
10 Gene Mapping to Genomics 273
App. A: Further Reading 301
App. B: Abbreviations 305
App. C: Glossary 309
App. D: Enzymes 323
App. E: Genes 327
App. F: Standard Genetic Code 331
App. G: Bacterial Species 333
Index 337
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)