Molecular Genetics of Cancer / Edition 2

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Overview

Molecular Genetics of Cancer, Second Edition, provides an authoritative and up to date review of the key genes known to be critical in the development or progression of cancer. Throughout the book, scientific advances and their clinical relevance are covered in detail, particularly in the light of findings concerning the inheritance of genes predisposing to tumorigenesis. The book is therefore a valuable source of reference for clinicians and genetic counsellors as well as researchers.

Audience: Oncologists, molecular geneticists, hematologists, and basic researchers.

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Product Details

  • ISBN-13: 9781859961698
  • Publisher: Taylor & Francis
  • Publication date: 4/1/2001
  • Edition number: 2
  • Pages: 536
  • Product dimensions: 6.14 (w) x 9.21 (h) x 1.19 (d)

Table of Contents

Contributors
Abbreviations
Preface
1 Basic principles in cancer genetics 1
2 Defining genetic changes associated with cutaneous malignant melanoma 33
3 The genetics of breast and ovarian cancer 53
4 Genetics of von Hippel-Lindau disease 81
5 Genetics of NF1 and NF2 95
6 Genetics of gastric cancer 115
7 Multiple endocrine neoplasia type 1 149
8 Multiple endocrine neoplasia type 2 171
9 TP53 in cancer origin and treatment 195
10 Colorectal cancer 233
11 Genetics of prostate cancer 255
12 Tuberous sclerosis complex 277
13 Retinoblastoma: patients, tumors, gene and protein contribute to the understanding of cancer 297
14 Genetics of Wilms tumor 317
15 Genetics of neuroblastoma 335
16 Genetics of brain tumors 363
17 Molecular genetics of lung cancer 387
18 Genetics of liver cancer 415
19 The genetics of bladder cancer 435
20 Genetics of rhabdomyosarcoma 461
21 Role of telomeres and telomerase in aging and cancer 483
Index 509
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