Molecular Hematology / Edition 3

Molecular Hematology / Edition 3

by Drew Provan, John Gribben
     
 

ISBN-10: 1405182318

ISBN-13: 9781405182317

Pub. Date: 05/17/2010

Publisher: Wiley

Now in its third edition, Molecular Hematology has been thoroughly updated to incorporate recent advances in molecular research. The aim of the book remains the same – to provide a core knowledge base for those with little exposure to molecular biological techniques.

Molecular biology has had a significant impact on the understanding of blood

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Overview

Now in its third edition, Molecular Hematology has been thoroughly updated to incorporate recent advances in molecular research. The aim of the book remains the same – to provide a core knowledge base for those with little exposure to molecular biological techniques.

Molecular biology has had a significant impact on the understanding of blood diseases and this book shows how molecular techniques can be used in diagnosis and treatment. In each chapter the authors summarize the impact made by molecular research on the understanding of the pathogenesis of the disorder featured, and highlight the molecular strategies that exist, or are being currently investigated, for therapeutic purposes. There are six brand new chapters in this edition:

  • History and development of molecular biology
  • Pharmacogenomics
  • Anemia of chronic disease
  • Molecular pathogenesis of malaria
  • Molecular basis of transplantation
  • Cancer stem cells

Presented in an extremely readable style with clear two-color line diagrams, this book is designed for the non-specialist and will be an invaluable resource for all trainee hematologists.

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Product Details

ISBN-13:
9781405182317
Publisher:
Wiley
Publication date:
05/17/2010
Edition description:
New Edition
Pages:
428
Product dimensions:
8.60(w) x 10.90(h) x 1.10(d)

Related Subjects

Table of Contents

1Beginnings : the molecular pathology of hemoglobin1
2Molecular cytogenetics18
3Stem cells25
4The genetics of acute myeloid leukemias41
5Secondary myelodysplasia/acute myelogenous leukemia - assessment of risk47
6Detection of minimal residual disease in hematological malignancies53
7Chronic myeloid leukemia72
8Myelodysplastic syndromes82
9Myeloproliferative disorders90
10Lymphoid neoplasms105
11The molecular biology of multiple myeloma115
12The molecular basis of anemia125
13The molecular basis of iron metabolism150
14Hemoglobinopathies due to structural mutations159
15Molecular coagulation and thrombophilia173
16The molecular basis of hemophilia184
17The molecular basis of von Willebrand disease199
18Platelet disorders210
19The molecular basis of blood cell alloantigens225
20Functions of blood group antigens241
21Autoimmune hematological disorders251
22Hematopoietic growth factors267
23Molecular therapeutics in hematology280
24Gene expression profiling in the study of lymphoid malignancies298

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