Molecular Mechanisms of Programmed Cell Death

Overview

This volume presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. Top scientists from around the world wrote on current progresses to help establish and/or strengthen communications between scientists from the West and those in Asia.

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Overview

This volume presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. Top scientists from around the world wrote on current progresses to help establish and/or strengthen communications between scientists from the West and those in Asia.

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Product Details

  • ISBN-13: 9781441934048
  • Publisher: Springer US
  • Publication date: 12/6/2010
  • Edition description: Softcover reprint of hardcover 1st ed. 2003
  • Edition number: 1
  • Pages: 229

Table of Contents

1. Akt and Bcl-xL Are Independent Regulators of the Mihondrial Cell Death Pathways.- 2. Thyroid Hormone-Induced Apoptosis during Amphibian Metamorphosis.- 3. The Endoplasmic Reticulum Stress Response in Health and Disease.- 4. The Role of the PI3K Pathway in Anti-IgM (Anti-?) -Sensitive and -Resistant B-cell Lymphomas: Failure to Disengage PI3K Pathway Signaling Confers Anti-? Resistance on the CH12 B Cell Lymphoma.- 5. Signaling for Inducible Fas-Resistance in Primary B Lymphocytes.- 6. Apoptosis and Autoimmune Diseases.- 7. Oxidative Stress and Thymocyte Apoptosis.- 8. Activation-Induced Cell Death and T Helper Subset Differentiation.- 9. The Bax-/- Bak-/- Mouse: a Model for Apoptosis.- 10. Novel Transcriptional Regulatory Pathways of IL-3-Dependent Survival Responses.- 11. MAP-1 Is a Putative Ligand for the Multidomain Proapoptotic Protein Bax.- 12. The Mechanisms and Significance of Apoptotic Cell-Mediated Immune Regulation.- 13. Neuroprotection against Apoptosis: What Has it Got to Do with the Mood Stabilizer Lithium?.- 14. Apoptosis, Cancer, and Cancer Therapy.- 15. DNA Fragmentation in Mammalian Apoptosis and Tissue Homeostasis.- 16. Ubiquitin and Intracellular Aggregation: A Common Pathway of Neurodegeneration in Chronic Dementia?.- 17. The Mechanism of Apoptosis Regulation by IAP Antagonist Smac/DIABLO.- 18. Integration of TNF-? Signaling: Crosstalk between IKK, JNK, and Caspases.

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