Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Second Edition / Edition 2

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Turn to the classic primer of Molecular Neuroscience for a complete understanding of nervous system function and its relationship to human neurologic disorders

A Doody's Core Title for 2011!


"This is an outstanding new introductory textbook on neuropharmacology and its implications for cognitive neuroscience. Anyone who wants to keep abreast of this rapidly emerging science needs to learn the fundamentals which this book would help facilitate. I highly recommend it."—Doody's Review Service

Molecular Neuropharmacology offers a clear, thorough explanation of the molecular functioning of the nervous system in normal and disease states. More than three hundred concept-clarifying full-color illustrations along with didactic text boxes provide an in-depth understanding of nerve cell receptors, their effectors and second messenger targets, and the molecular genetics that are often impacted by these systems. You will also learn how malfunction of these molecular systems relates to human disease and the corresponding medical treatment.

Molecular Neuropharmacology is the most relevant, well-written resource available to help you make the connection between neuropharmacology and clinical neuroscience.

Numerous figures and didactic boxes help you understand and remember complex subject matter for efficient, on-the-spot review. The book's all-inclusive, high-yield coverage includes:

  • The fundamentals of neuropharmacology
  • Neural substrates of drug action
  • The neuropharmacology of specific functions and disorders—encompassing control of movement, mood and emotion, memory and dementia, and other vital areas
  • NEW! A streamlined redesign that makes the book even more practical and accessible than ever
  • NEW! More illustrations—all 300 now in full color!
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Editorial Reviews

Doody's Review Service
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: This is a top-notch new textbook covering the neuropharmacology basis of cognitive neuroscience. The textbook is a great introduction to the fundamentals of neuropharmacology, the neural mechanisms involved in the actions of drugs, and neurophysiology/neuropharmacology of cognition, emotion, and memory. Written and edited by internationally recognized leaders in the field, this book is an outstanding contribution to neuroscientific education.
Purpose: The purpose of this textbook is help the reader have a deeper appreciation of drug action by developing an understanding of the "... entire sequence of events commencing with drug action". The editors correctly assert that "...only with an awareness of the many steps in the process can we grasp how a drug changes complex nervous system functions such as movement, cognition, pain or mood".
Audience: The targeted audience is wide, according to the editors, and includes: undergraduate and graduate students, students in the medical and heath professions, and residents in psychiatry, neurology, neurosurgery, rehabilitation medicine, anesthesiology as well as practicing clinicians.
Features: The book features 498 pages divided into 3 parts containing 19 chapters including an index. Part 1 focuses on fundamental issues and includes chapters on cell signaling, synaptic transmission and signal transduction. Part 2 reviews the neurophysiologic basis of drug action with chapters on excitatory/inhibitory amino acids, monoamines, acetylcholine and orexin, neuropeptides, and atypical neurotransmitters. The last section, which I thought was the best part of the book, is on higher brain functions and contains chapters on the autonomic nervous system, pain and inflammation, sleep, higher cognitive functions and behavior, mood and emotion, addiction, psychoses, neurodegeneration, seizure disorders, and stroke and migraine. The textbook is filled with wonderful diagrams and figures. Each chapter ends with a list of suggested readings. The index was useful as well.
Assessment: This is an outstanding new introductory textbook on neuropharmacology and its implications for cognitive neuroscience. Anyone who wants to keep abreast of this rapidly emerging science needs to learn the fundamentals which this book would help facilitate. I highly recommend it.
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Product Details

  • ISBN-13: 9780071481274
  • Publisher: McGraw-Hill Professional Publishing
  • Publication date: 10/27/2008
  • Edition description: New Edition
  • Edition number: 2
  • Pages: 516
  • Sales rank: 515,354
  • Product dimensions: 7.00 (w) x 10.00 (h) x 0.70 (d)

Meet the Author

Eric J. Nestler, MD, PhD

Nash Family Professor of Neuroscience

Chairman, Department of Neuroscience and

Director of the Mount Sinai Brain Institute

Mount Sinai School of Medicine

New York, NY

Stephen E. Hyman, MD

Professor of Neurobiology

Harvard Medical School


Harvard University

Cambridge, MA

Robert C. Malenka, MD, PhD

Nancy Friend Pritzker Professor of Psychiatry and Behavioral Sciences

Director, Nancy Friend Pritzker Laboratory

Stanford University School of Medicine

Palo Alto, CA

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Table of Contents

Part 1: Fundamentals of Neuropharmacology
1. Basic Principles of Neuropharmacology
2. Cellular Basis of Communication
3. Synaptic Transmission
4. Signal Transduction to the Brain
Part 2: Neural Substrates of Drug Action
5. Excitatory and Inhibitory Amino Acids
6. Widely Projecting Systems: Monoamines, Acetylcholine, and Orexin
7. Neuropeptides
8. Atypical Neurotransmitters
Neuropharmacology of Neural Systems and Disorders
9. Autonomic Nervous System
10. Neural and Neuroendocrine Control of the Internal Milieu
11. Pain and Inflammation
12. Sleep and Arousal
13. Higher Cognitive Function and Behavioral Control
14. Mood and Emotion
15. Reinforcement and Addictive Disorders
16. Schizophrenia and Other Psychoses
17. Neurodegeneration
18. Seizure Disorders
19. Stroke and Migraine

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Customer Reviews

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