Molecular Physiology and Metabolism of the Nervous System: A Clinical Perspective

Molecular Physiology and Metabolism of the Nervous System: A Clinical Perspective

by Gary A. Rosenberg
     
 

The molecular basis for the physiology of the brain has advanced enormously in the past twenty years with an influx of new information gleaned through technological developments in neuroimaging and molecular discoveries. Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and

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Overview

The molecular basis for the physiology of the brain has advanced enormously in the past twenty years with an influx of new information gleaned through technological developments in neuroimaging and molecular discoveries. Molecular Physiology and Metabolism of the Nervous System, authored by Gary A. Rosenberg, an authority on the physiology of brain fluids and metabolism, combines the classic physiology that dates back to the beginning of the nineteenth century with the advances in molecular sciences, providing a strong framework for understanding the diseases that are commonly treated by neurologists. Molecular Physiology and Metabolism of the Nervous System focuses on the current neuropathology and implications of cerebrospinal fluid diseases and diseases of the blood-brain barrier: how the two affect stroke, infection, brain tumors, and increased intracranial pressure. The book discusses the effects of blood flow in stroke and dementia, the disruption of the blood-brain barrier in neuroinflammation, and the dysfunction due to brain edema and increased intracranial pressure. Molecular Physiology and Metabolism of the Nervous System is necessary reading for neurologists, neuroscientists, and residents in neurology, neurosurgery, and psychiatry, giving them a strong grounding in physiology and metabolism that will aid them in diagnosis and treatment.

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Editorial Reviews

From the Publisher
"Molecular Physiology and Metabolism of the Nervous System is logically presented to introduce the reader to the physiology and anatomy of the cerebrospinal and interstitial fluids for understanding the pathophysiology of brain edema and other current topics such as hypoxic/ischemic brain damage and disorders of the cerebrospinal circulation. In addition, there are chapters that explore novel concepts of the neuro(glio)vascular unit and the evolving story of vascular cognitive impairment in Alzheimer's disease he book is oriented completely to the human brain and is, thus, especially appropriate for clinical education. The writing style is compact, yet flowing and provides more than a comprehensive entry level basic approach, but also the second level content often missing from similar style works in other areas." — Joseph C. LaManna, PhD, Department of Physiology & Biophysics, School of Medicine, Case Western Reserve University, Cleveland, OH

"Dr. Gary Rosenberg has artfully crafted a monograph, Brain Molecular Physiology and Metabolism, on how the brain and its blood supply and cerebrospinal fluid circulation work at a cellular level. The book is written by a research scientist who is also an experienced clinician. The writing is aimed at clinicians helping them to understand brain physiology. Brain images and neuropathology specimens show snapshots of anatomy and pathology that must be supplemented by physiology and pathophysiology for diagnosis and for grasping the nature of patient's symptoms and signs. Rosenberg's book ably fills this gap which is so crucial to understanding disease mechanisms and their management. The writing is clear and easily understood and relevant to clinicians." — Louis R. Caplan, MD,Professor of Neurology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA

"This book is an eclectic collection of the protean tastes of Dr. Rosenberg. It includes materials that are old friends such as the Krebs cycle, to the most current concepts of molecular physiology and biochemistry. Up until now, most of the most modern topics have not yet produced clinically useful discoveries. However, we can anticipate that 20 years from now some of the work that is outlined in chapters of this book will have similar effects on morbidity and mortality. In summary, this book is a useful collection of a variety of topics which I personally find extremely interesting and I hope that you will think that as well. Dr. Rosenberg and his colleagues have put a good deal of thought into this book, and the effort shows." — Justin A Zivin, MD, PhD, Department of Neurosciences, UC San Diego School of Medicine, La Jolla, CA and Department of Neurology, San Diego VA Healthcare System, San Diego, CA

"Molecular Physiology and Metabolism of the Nervous System describes most accurately the underlying pathophysiology of numerous neurological disorders such as Idiopathic Intracranial Hypertension, hydrocephalus, ischemic/hypoxic brain injury as well as Vascular Cognitive Impairment and Alzheimer's disease. Combining the complex knowledge in the field of molecular neurology with a clear writing style and organization makes this book an outstanding and valuable tool not only for graduate and doctoral students, research-oriented medical professionals and neuroscientists but also for anyone interested in neurophysiology. This book is well-referenced, includes recent scientific findings and presents the most up-to-date principles in this field. We highly recommend this exceptional work by a world leading neuroscientist and clinical neurologist." — Paul Reiner Krafft, MD and John H. Zhang MD, PhD, Loma Linda University School of Medicine, Loma Linda, CA

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Product Details

ISBN-13:
9780195394276
Publisher:
Oxford University Press
Publication date:
04/30/2012
Series:
Contemporary Neurology Series, #82
Pages:
240
Product dimensions:
7.10(w) x 10.00(h) x 0.90(d)

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