Morphogenesis: The Cellular and Molecular Processes of Developmental Anatomy

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Overview

This timely account provides a comprehensive contemporary analysis of morphogenetic processes in vertebrate and invertebrate embryos. Morphogenesis, the generation of tissue organization in embryos, is an increasingly important subject. This is partly because the techniques for investigating many morphogenetic mechanisms have only recently become available and partly because studying the genomic basis of embryogenesis requires an understanding of the developmental phenotype. Following an introduction covering case studies and historical and technical approaches, the book reviews the mechanistic roles of extracellular matrices, cell membranes and the cytoskeleton in morphogenesis. A detailed discussion of how mesenchymal and epithelial cells cooperate to build a wide range of tissues is also included. The book concludes with a dynamical analysis of the subject. With its extensive literature review (more than 500 titles), this book will interest developmental biologists and will also serve as an advanced textbook for postgraduate and final year students.

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Editorial Reviews

From the Publisher
"...well written, thoughtful, and entertaining, and clearly fills a need for an up-to-date account of the subject." Cell

"...excellent critical review of our current knowledge of the physical mechanisms by which organs and tissues are constructed during embryonic development." Science

"...a splendid book. It reads like a textbook of (largely vertebrate) morphogenesis. It is comprehensive, extensively referenced and nicely illustrated. It is also up to date, as well as usefully 'historical' in several places." George M. Malacinski, Quarterly Review of Biology

"Well written, and overall one of the best books in developmental biology as a whole." L.M. Van Valen, Evolutionary Theory and Review

"Morphogenesis, the generation of tissue organization in embryos, is becoming an increasingly important subject. This book provides a comprehensive and contemporary analysis of morphogenetic processes in vertebrate and inbertebrate embryos." H.-J. Halbhuber, Cellular and Molecular Biology

"Although Bard presents a focused and technical discussion of morphogenesis, the clarity and depth of the synthesis that he provides render the book appropriate for graduate students and biological scientists specializing in organogenesis, as well as individuals more generally interested in topics in developmental biology....would be an excellent textbook for advanced courses in developmental biology." Lee Xenakis Blonder, American Journal of Human Biology

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Product Details

  • ISBN-13: 9780521436120
  • Publisher: Cambridge University Press
  • Publication date: 5/28/2006
  • Series: Developmental and Cell Biology Monographs
  • Edition description: New Edition
  • Pages: 313
  • Product dimensions: 5.98 (w) x 8.98 (h) x 0.75 (d)

Table of Contents

Preface; Acknowledgements; 1. Introduction; 2. Background; 3. Case studies; 4. The molecular basis of morphogenesis; 5. The morphogenetic properties of mesenchyme; 6. The epithelial repertoire; 7. A dynamic framework for morphogenesis; 8. Pulling together some threads; Appendices; References; Index.

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