Overview

The cardiovascular system is the first functional organ system to develop in the vertebrate embryo. Embryonic growth and differentiation essentially depend on transport of nutrients and waste through the early vasculature, and certain events in morphogenesis are thought to be influenced by the hemodynamic forces of the beating heart. The vasculature not only serves as a "nutrient and waste pipeline" but is also a major communication system between distant organs and tissues.
The...
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Morphogenesis of Endothelium

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Overview

The cardiovascular system is the first functional organ system to develop in the vertebrate embryo. Embryonic growth and differentiation essentially depend on transport of nutrients and waste through the early vasculature, and certain events in morphogenesis are thought to be influenced by the hemodynamic forces of the beating heart. The vasculature not only serves as a "nutrient and waste pipeline" but is also a major communication system between distant organs and tissues.
The vascular endothelial cell mediates vascular growth, permeability, integrity and interactions with blood cells. In most tissues the endothelium itself is highly specialized to meet the particular needs of the tissue in terms of quality and quantity of incoming and outgoing molecules and messages. The areas covered by Morphogenesis of Endothelium include the formation of blood vessels in embryonic tissues by vasculogenesis and angiogenesis and the differentiation of endothelium in organs. The contributors are leaders
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Editorial Reviews

Booknews
Fifteen studies explore diverse questions concerning the development of vascular endothelial cells. Among the topics: endothelial fenestrae and fenestral diaphragms, adhesian molecules in endothelial cells and their role in vascular morphogenesis, vascular development (including retinal vasculature), the blood-brain barrier, pulmonary microvasculature, the kidney vascular system, the liver vascular system, and the limb bud vascular system. Risau, deceased, was director of the Max-Planck-Institute in Bad Neuheim; Rubanyi is a researcher at Berlex Biosciences in Richmond, California. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780203304358
  • Publisher: Taylor & Francis, Inc.
  • Publication date: 10/1/2000
  • Sold by: Barnes & Noble
  • Format: eBook
  • Pages: 312
  • File size: 10 MB

Table of Contents

Structural, Biochemical and Functional Differentiation of the Vascular Endothelium
Endothelial Fenestrae and Fenestral Diaphragms
Adhesion Molecules in Endothelial Cells and Their Role in Vascular Morphogenesis
Development of the Vascular Endothelium in Avian Embryos
Development of the Heart, Large Vessels and Coronary Vasculature
The Development of the Retinal Vasculature
Development of the Blood-Brain-Barrier
Development and Growth of the Pulmonary Microvasculature
Development of the Kidney Vascular System
Development of the Liver Vascular System
Development of the Limb Bud Vascular System
Development of the Vascular System in Skeletal Muscle
Development of the Vascular System in the Corpus Luteum
Development of the Vascular System in the Placenta
The Development of the Lymph Node Vasculature
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