MRI: Basic Principles and Applications / Edition 4

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For Its Fourth Edition, the acclaimed MRI: Basic Principles and Applications has been rigorously revised, enabling readers to quickly master the principles and take advantage of all the latest MRI applications. Among the new materials are fresh and updated discussions on 3D imaging, real-time imaging, cardiac imaging, and parallel acquisition techniques. In addition, readers will find dozens of brand-new images to illustrate key concepts. Moreover, clinical protocols have been thoroughly updated and revised to reflect current methodologies.

Throughout the book, readers will find easy-to-follow coverage of all the latest findings, technologies, and techniques, including:

Nephrotoxic effects of gadolinium-based contrast media

New scan techniques, including radial scanning

Parallel acquisition and cardiovascular imaging techniques

New applications, including spin tagging and diffusion tensor imaging

3 Tesla and 7 Tesla scanning

Hardware innovations, including large-scale array coils

New motion compensation techniques

With its clear explanations and ample illustrations, this Fourth Edition maintains all the hallmarks of the previous edition that have made this book a fixture in MRI labs around the world. Students and practitioners—from physicians to radiologists to technicians—will gain a full, accurate understanding of the underlying physics and the clinical applications of MRI, all with a minimum of mathematical formulas and technical details.

The book contains black-and-white illustrations.

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Editorial Reviews

Amy Herlihy
This book discusses the basics of MRI, pulse sequences, and hardware requirements. The purpose is to give the reader a basic overview of MR physics, imaging techniques, and hardware. Targeted at a broad audience, the authors present the ideas clearly, avoiding the more difficult math and physics aspects. This book would be ideally suited to technicians and radiologists who are new to MRI and to radiology residents. I would recommend this to MRI graduate students as a first-semester reading. Although nicely presented, this book is short on some figures. It could use a graphical explanation of gradient echoes, sequence timing, and gradient lobe usage. MR images are not always easy to reproduce, but some figures could be drastically improved. The demonstration of wrap-around (or frequency undersampling) could be better. The abundance of pulse sequence diagrams is quite useful. Given the speed at which the field of MRI evolves, up-to-date information is important. This book does a nice job of discussing the major points of MRI, presenting current imaging techniques and hardware considerations. Although there are several such books out, this is a simple, easily readable book that covers all aspects of MRI, from the basic physics, to specific pulse sequences, to hardware requirements.
Acta Radiologica
...a nice introduction to this field. For anyone thinking of buying a book about basic MR imaging, why not buy this one?
Presents the core concepts of magnetic resonance imaging for clinicians and technologists who might not have an extensive background in physics. Discusses basic physics of MRI, the hardware used in MRI systems, and the issues involved in developing imaging protocols, and gives an overview of the guiding principles for the clinical application of MRI. Topics include: pulse sequences, artifacts, fat suppression techniques, MR angiography, and contrast agents. Annotation c. Book News, Inc., Portland, OR (
Doody's Review Service
Reviewer: William R. Hendee, PhD (Medical College of Wisconsin)
Description: This is the third edition of an introduction to the research, technology, and clinical applications of magnetic resonance imaging (MRI) that has become standard reading material for radiology residents. The second edition was published in 1999 and the first edition in 1995.
Purpose: The purpose is to provide readers with the knowledge of the tools needed to assess various MRI modalities and to understand and apply the contrast mechanisms inherent in any of the modalities. This information is an essential ingredient in the education of any radiologist. The book meets its objectives very well.
Audience: The primary audience for this book is radiology residents and the book has become standard for residents in training programs across the nation. However, it serves well as an introductory book for anyone wishing to learn about MRI. Certainly, the authors are recognized authors in the field.
Features: The book provides an introduction to the science and technology of magnetic resonance imaging, enabling in-depth assessment of contrast enhancement mechanisms. A final chapter on clinical applications is reinforced by clinical images throughout the book. The authors write well and have chosen their examples very well.
Assessment: This book is a very well written book and has wonderful illustrations of technical principles, many of which are clinical images. New editions every four years might seem to be excessively frequent, but the field of magnetic resonance imaging is changing quickly, both technically and clinically.
From the Publisher
"...a useful tool for those engaged in the technical aspects of MRI...a practical basic guide for general radiologists, technologists and their students." (The International MS Journal, September 2004)

"...successful in transferring key ideas in an undaunting and progressive manner...thoroughly deserves a place on the bookshelf..." (NMR in Biomedicine, Vol 17(4), June 2004)

"…it will reward the reader with an understanding of the principles underpinning nuclear magnetic resonance." (Yale Journal of Biology and Medicine, May 2003)

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780470500989
  • Publisher: Wiley
  • Publication date: 5/3/2010
  • Edition description: New Edition
  • Edition number: 4
  • Pages: 264
  • Sales rank: 1,084,662
  • Product dimensions: 6.42 (w) x 9.37 (h) x 0.53 (d)

Table of Contents

Preface ix

Preface to the Third Edition x

Preface to the Second Edition xi

Preface to the First Edition xiii

1 Production of Net Magnetization 1

2 Concepts of Magnetic Resonance 9

3 Relaxation 17

1 T1 Relaxation and Saturation 18

2 T2 Relaxation, T2* Relaxation, and Spin Echoes 21

4 Principles of Magnetic Resonance Imaging: Part 1 27

1 Slice Selection 29

2 Readout or Frequency Encoding 31

3 Phase Encoding 34

4 Sequence Looping 36

5 Principles of Magnetic Resonance Imaging: Part 2 41

1 Frequency-Selective Excitation 41

2 Composite Pulses 47

3 Raw Data and Image Data Matrices 47

4 Raw Data and k Space 50

5 Reduced k-Space Techniques 53

6 Reordered k-Space Filling Techniques 56

7 Other k-Space-Filling Techniques 58

8 Phased-Array Coils 61

9 Parallel Acquisition Methods 64

6 Pulse Sequences 69

1 Spin Echo Sequences 71

2 Gradient Echo Sequences 74

3 Echo Planar Imaging Sequences 80

4 Magnetization-Prepared Sequences 82

7 Measurement Parameters and Image Contrast 91

1 Intrinsic Parameters 92

2 Extrinsic Parameters 95

3 Parameter Trade-offs 97

8 Signal-Suppression Techniques 101

1 Spatial Presaturation 102

2 Magnetization Transfer Suppression 103

3 Frequency-Selective Saturation 106

4 Nonsaturation Methods 108

9 Artifacts 111

1 Motion Artifacts 111

2 Sequence/Protocol-Related Artifacts 115

3 External Artifacts 130

10 Motion Artifact Reduction Techniques 137

1 Acquisition Parameter Modification 138

2 Triggering and Gating 139

3 Flow Compensation 144

4 Radial-Based Motion Compensation 145

11 Magnetic Resonance Angiography 147

1 Time-of-FIight MRA 149

2 Phase-Contrast MRA 154

3 Maximum-Intensity Projection 157

12 Advanced Imaging Applications 161

1 Diffusion 161

2 Perfusion 167

3 Functional Brain Imaging 171

4 Ultrahigh Field Imaging 172

5 Noble Gas Imaging 174

13 Magnetic Resonance Spectroscopy 177

1 Additional Concepts 177

2 Localization Techniques 182

3 Spectral Analysis and Postprocessing 186

4 Ultrahigh Field Spectroscopy 189

14 Instrumentation 191

1 Computer System 191

2 Magnet System 195

3 Gradient System 196

4 Radio-frequency System 198

5 Data Acquisition System 201

6 Summary of System Components 202

15 Contrast Agents 205

1 Intravenous Agents 206

2 Oral Agents 212

16 Safety 213

1 Base Magnetic Field 214

2 Cryogens 215

3 Gradients 215

4 RF Power Deposition 216

5 Contrast Media 216

17 Clinical Applications 219

1 General Principles of Clinical MR Imaging 220

2 Examination Design Considerations 221

3 Protocol Considerations for Anatomical Regions 222

4 Recommendations for Specific Sequences and Clinical Situations 237

References and Suggested Reading 241

Index 245

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