MRI: Basic Principles and Applications [NOOK Book]


Fourth Edition Brings This Popular Guide Thoroughly Up To Date With The Latest MRI Findings, Techniques, And Applications

For its Fourth Edition, the acclaimed MRI: Basic Principles and Applications has been rigorously revised, enabling readers to quickly master the principles and take advantage of all the latest MRI applications. Among the new materials are fresh and updated discussions on 3D imaging, real-time imaging, cardiac imaging, and parallel acquisition techniques. In ...

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MRI: Basic Principles and Applications

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Fourth Edition Brings This Popular Guide Thoroughly Up To Date With The Latest MRI Findings, Techniques, And Applications

For its Fourth Edition, the acclaimed MRI: Basic Principles and Applications has been rigorously revised, enabling readers to quickly master the principles and take advantage of all the latest MRI applications. Among the new materials are fresh and updated discussions on 3D imaging, real-time imaging, cardiac imaging, and parallel acquisition techniques. In addition, readers will find dozens of brand-new images to illustrate key concepts. Moreover, clinical protocols have been thoroughly updated and revised to reflect current methodologies.

Throughout the book, readers will find easy-to-follow coverage of all the latest findings, technologies, and techniques, including:

  • Nephrotoxic effects of gadolinium-based contrast media

  • New scan techniques, including radial scanning

  • Parallel acquisition and cardiovascular imaging techniques

  • New applications, including spin tagging and diffusion tensor imaging

  • 3 Tesla and 7 Tesla scanning

  • Hardware innovations, including large-scale array coils

  • New motion compensation techniques

With its clear explanations and ample illustrations, this Fourth Edition maintains all the hallmarks of the previous edition that have made this book a fixture in MRI labs around the world. Students and practitioners—from physicians to radiologists to technicians—will gain a full, accurate understanding of the underlying physics and the clinical applications of MRI, all with a minimum of mathematical formulas and technical details.

From Reviews of the Third Edition

". . . successful in transferring key ideas in an undaunting and progressive manner . . . thoroughly deserves a place on the bookshelf."
NMR in Biomedicine, Vol 17(4), June 2004

". . . it will reward the reader with an understanding of the principles underpinning nuclear magnetic resonance."
Yale Journal of Biology and Medicine, May 2003

The book contains black-and-white illustrations.

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Editorial Reviews

Amy Herlihy
This book discusses the basics of MRI, pulse sequences, and hardware requirements. The purpose is to give the reader a basic overview of MR physics, imaging techniques, and hardware. Targeted at a broad audience, the authors present the ideas clearly, avoiding the more difficult math and physics aspects. This book would be ideally suited to technicians and radiologists who are new to MRI and to radiology residents. I would recommend this to MRI graduate students as a first-semester reading. Although nicely presented, this book is short on some figures. It could use a graphical explanation of gradient echoes, sequence timing, and gradient lobe usage. MR images are not always easy to reproduce, but some figures could be drastically improved. The demonstration of wrap-around (or frequency undersampling) could be better. The abundance of pulse sequence diagrams is quite useful. Given the speed at which the field of MRI evolves, up-to-date information is important. This book does a nice job of discussing the major points of MRI, presenting current imaging techniques and hardware considerations. Although there are several such books out, this is a simple, easily readable book that covers all aspects of MRI, from the basic physics, to specific pulse sequences, to hardware requirements.
Acta Radiologica
...a nice introduction to this field. For anyone thinking of buying a book about basic MR imaging, why not buy this one?
Presents the core concepts of magnetic resonance imaging for clinicians and technologists who might not have an extensive background in physics. Discusses basic physics of MRI, the hardware used in MRI systems, and the issues involved in developing imaging protocols, and gives an overview of the guiding principles for the clinical application of MRI. Topics include: pulse sequences, artifacts, fat suppression techniques, MR angiography, and contrast agents. Annotation c. Book News, Inc., Portland, OR (
Doody's Review Service
Reviewer: William R. Hendee, PhD (Medical College of Wisconsin)
Description: This is the third edition of an introduction to the research, technology, and clinical applications of magnetic resonance imaging (MRI) that has become standard reading material for radiology residents. The second edition was published in 1999 and the first edition in 1995.
Purpose: The purpose is to provide readers with the knowledge of the tools needed to assess various MRI modalities and to understand and apply the contrast mechanisms inherent in any of the modalities. This information is an essential ingredient in the education of any radiologist. The book meets its objectives very well.
Audience: The primary audience for this book is radiology residents and the book has become standard for residents in training programs across the nation. However, it serves well as an introductory book for anyone wishing to learn about MRI. Certainly, the authors are recognized authors in the field.
Features: The book provides an introduction to the science and technology of magnetic resonance imaging, enabling in-depth assessment of contrast enhancement mechanisms. A final chapter on clinical applications is reinforced by clinical images throughout the book. The authors write well and have chosen their examples very well.
Assessment: This book is a very well written book and has wonderful illustrations of technical principles, many of which are clinical images. New editions every four years might seem to be excessively frequent, but the field of magnetic resonance imaging is changing quickly, both technically and clinically.
From the Publisher
"...a useful tool for those engaged in the technical aspects of MRI...a practical basic guide for general radiologists, technologists and their students." (The International MS Journal, September 2004)

"...successful in transferring key ideas in an undaunting and progressive manner...thoroughly deserves a place on the bookshelf..." (NMR in Biomedicine, Vol 17(4), June 2004)

"…it will reward the reader with an understanding of the principles underpinning nuclear magnetic resonance." (Yale Journal of Biology and Medicine, May 2003)

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780470920862
  • Publisher: Wiley
  • Publication date: 1/14/2011
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 4
  • Pages: 264
  • File size: 10 MB

Meet the Author

Mark A. Brown, PhD, is Senior Technical Instructor at Siemens Medical Solutions Training and Development Center and also holds an adjunct research professorship in the Department of Radiology, University of North Carolina School of Medicine. His research interests include relaxation and exchange phenomena and in vivo nuclear magnetic resonance spectroscopy and imaging.

Richard Semelka, MD, is Director of Magnetic Resonance Services, Professor, and Vice Chairman of Radiology at the University of North Carolina-Chapel Hill Medical School. He received his medical degree and residency training in radiology in his native Canada at the University of Manitoba, and completed a clinical research fellowship in MRI of the body at the University of California at San Francisco. Dr. Semelka has authored over 150 peer-reviewed articles, 4 textbooks, and is an internationally acclaimed authority in the field.

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Table of Contents


Preface to the Third Edition.

Preface to the Second Edition.

Preface to the First Edition.

1. Production of Net Magnetization.

2. Concepts of Magnetic Resonance.

3. Relaxation.

3-1. T1 Relaxation and Saturation.

3-2. T2 Relaxation, T2* Relaxation, and Spin Echoes.

4. Principles of Magnetic Resonance Imaging: Part 1.

4-1. Slice Selection.

4-2. Readout or Frequency Encoding.

4-3. Phase Encoding.

4-4. Sequence Looping.

5. Principles of Magnetic Resonance Imaging: Part 2.

5-1. Frequency-Selective Excitation.

5-2. Composite Pulses.

5-3. Raw Data and Image Data Matrices.

5-4. Raw Data and k Space.

5-5. Reduced k-Space Techniques.

5-6. Reordered k-Space Filling Techniques.

5-7. Other k-Space-Filling Techniques.

5-8. Phased-Array Coils.

5-9. Parallel Acquisition Methods.

6. Pulse Sequences.

6-1. Spin Echo Sequences.

6-2. Gradient Echo Sequences.

6-3. Echo Planar Imaging Sequences.

6-4. Magnetization-Prepared Sequences.

7. Measurement Parameters and Image Contrast.

7-1. Intrinsic Parameters.

7-2. Extrinsic Parameters.

7-3. Parameter Trade-offs.

8. Signal-Suppression Techniques.

8-1. Spatial Presaturation.

8-2. Magnetization Transfer Suppression.

8-3. Frequency-Selective Saturation.

8-4. Nonsaturation Methods.

9. Artifacts.

9-1. Motion Artifacts.

9-2. Sequence/Protocol-Related Artifacts.

9-3. External Artifacts.

10. Motion Artifact Reduction Techniques.

10-1. Acquisition Parameter Modifi cation.

10-2. Triggering and Gating.

10-3. Flow Compensation.

10-4. Radial-Based Motion Compensation.

11. Magnetic Resonance Angiography.

11-1. Time-of-Flight MRA.

11-2. Phase-Contrast MRA.

11-3. Maximum-Intensity Projection.

12. Advanced Imaging Applications.

12-1. Diffusion.

12-2. Perfusion.

12-3. Functional Brain Imaging.

12-4. Ultrahigh Field Imaging.

12-5. Noble Gas Imaging.

13. Magnetic Resonance Spectroscopy.

13-1. Additional Concepts.

13-2. Localization Techniques.

13-3. Spectral Analysis and Postprocessing.

13-4. Ultrahigh Field Spectroscopy.

14. Instrumentation.

14-1. Computer System.

14-2. Magnet System.

14-3. Gradient System.

14-4. Radio-frequency System.

14-5. Data Acquisition System.

14-6. Summary of System Components.

15. Contrast Agents.

15-1. Intravenous Agents.

15-2. Oral Agents.

16. Safety.

16-1. Base Magnetic Field.

16-2. Cryogens.

16-3. Gradients.

16-4. RF Power Deposition.

16-5. Contrast Media.

17. Clinical Applications.

17-1. General Principles of Clinical MR Imaging.

17-2. Examination Design Considerations.

17-3. Protocol Considerations for Anatomical Regions.

17-4. Recommendations for Specifi c Sequences and Clinical Situations.

References and Suggested Reading.


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