Multiple Cholecystokinin Receptors in the CNS

Multiple Cholecystokinin Receptors in the CNS

by Colin T. Dourish
     
 

Cholecystokinin (CCK) is found in high concentrations in mammalian brain where it appears to act as a neurotransmitter. CCK has been implicated in a number of important physiological processes and disease states, including feeding and feeding disorders, nociception, schizophrenia, movement disorders, anxiety, and panic disorder. The recent increase in interest in

Overview

Cholecystokinin (CCK) is found in high concentrations in mammalian brain where it appears to act as a neurotransmitter. CCK has been implicated in a number of important physiological processes and disease states, including feeding and feeding disorders, nociception, schizophrenia, movement disorders, anxiety, and panic disorder. The recent increase in interest in CCK is mainly attributable to the development of potent selective CCK receptor antagonists. These drugs have proved to be valuable research tools and may also prove useful as therapeutic agents. This volume reviews the most recent data on the role of CCK in normal and abnormal brain function. It brings together contributors from the leading researchers in the field of CCK neurobiology. Particular emphasis is placed on the roles of CCK receptor subtypes (CCK-A and CCK-E) which have been determined using selective antagonists.

Product Details

ISBN-13:
9780198577560
Publisher:
Oxford University Press, USA
Publication date:
10/22/1992
Pages:
580
Product dimensions:
6.38(w) x 9.50(h) x 1.44(d)

Meet the Author

Merck Sharp & Dohme Research Laboratories, Neuroscience Research Centre, Harlow

University of Birmingham

both at the Neuroscience Research Centre

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