Multiple Sclerosis and Related Disorders: Diagnosis, Medical Management, and Rehabilitation

Multiple Sclerosis and Related Disorders: Diagnosis, Medical Management, and Rehabilitation

by Alexander Rae-Grant, Robert Fox, Francois Bethoux
     
 

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Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients. Information on disease history, pathophysiology, and biology is included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders.

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Overview

Multiple Sclerosis and Related Disorders provides evidence-based data and experience-based guidance for delivering quality long-term care to MS patients. Information on disease history, pathophysiology, and biology is included to provide clinicians with a framework for understanding current diagnosis, monitoring, and treatment strategies for these disorders. In addition to thoroughly reviewing the newest disease-modifying treatments, the authors have devoted significant focus to the symptoms that frequently manifest and their treatment options. Symptoms and functional limitations are the “face of the disease” for patients, and present their own set of challenges for practitioners.

The book proceeds through diagnosis (initial symptoms, criteria and classification, imaging, lab tests, and differential diagnosis), approved treatments for the various MS types including emerging therapies where appropriate, symptom management, rehabilitative issues, general health and wellness, and an overview of MS clinical trials. Special populations, societal and family issues, and related disorders that are often mistaken for MS are also covered. Dedicated chapters on neuromyelitis optica and acute disseminated encephalomyelitis incorporate newer diagnostic criteria. Because comorbidities often make the management of MS-related disability more complex, the book addresses these comorbidities as part of a comprehensive management plan.

To enhance the clinical utility, critical-to-know information and management pearls are boxed for quick reference and most chapters include lists of “Key Points” for clinicians, and for patients and families. Illustrations, tables, graphs, assessment scales, and up-to-date MRI imaging inform the text throughout. The treatment chapters include specific recommendations where available and highlight areas of controversy. Illustrative cases go beyond the literature to amplify clinical recommendations and provide real-world guidance for practitioners. Illustrations, tables, graphs, assessment scales, and up-to-date MRI imaging inform the text throughout.

Multiple Sclerosis and Related Disorders features:

  • Comprehensive clinical reference for all members of the MS care team
  • Focus on practical approaches to diagnosis, treatment, counseling, and rehabilitative strategies
  • Reviews the latest disease modifying therapies
  • Extensive chapters on symptom management and women’s issues in MS
  • Edited and written primarily by expert clinicians at Cleveland Clinic/Mellen Center
  • Evidence- and experience-based guidance
  • Dedicated chapters on neuromyelitis optica and acute disseminated encephalomyelitis incorporating newer diagnostic criteria
  • Includes treatment guidelines and numerous illustrations, tables, scales; key information is highlighted for quick reference

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Editorial Reviews

Doody's Review Service
Reviewer: Elizabeth A. Shuster, M.D.(Mayo Clinic Florida)
Description: This concise but comprehensive book details practical approaches for the evaluation and care of patients with multiple sclerosis.
Purpose: The authors' objective was to provide an accessible book of core information for clinicians treating these patients.
Audience: Although clinical neurologists are the primary audience, this book would be most valuable to general physicians who treat MS patients in their clinics, nurse practitioners in neurology clinics, and residents rotating through MS clinics or managing MS patients in their continuity clinic. Neurologists who regularly treat MS patients are already familiar with most of the content, but will find it useful when teaching medical students, residents, and others on their team. The contributing authors have broad experience in treating patients with MS and are respected authorities in this field.
Features: The book is manageably sized and organized into seven parts and 38 chapters, and includes several unique features. Each chapter starts with key points for clinicians and ends with key points to share with patients. Important points also are highlighted throughout the book, which makes it easy to find the information again when needed. Part I includes a superb chapter on the pathophysiology of MS, written by Drs. Mahad and Ransohoff, that stresses the widespread tissue damage that occurs in MS in both the gray as well as the white matter of the brain and spinal cord. Part IV on rehabilitation and symptom management comprehensively covers the wide range of issues that come up in MS clinics. Chapter 21 on seizures, sleep, and transient symptoms and chapter 22 on ocular symptoms are particularly informational. Unfortunately, the reproduction of the MRI imaging is disappointing, but the authors did an admirable job of pointing out the specific details of MS lesions. I would have liked more in-depth discussions on some issues. For example, there is little discussion of the off label use of cyclophosphamide for aggressive or progressing MS. And while surgical procedures for bladder incontinence are mentioned, when the authors use them and how they chose a particular procedure is not detailed.
Assessment: This concise, well-written book is surprisingly comprehensive for its size. It includes some unique features that make it easy to access what is in each chapter. It will be valuable as a reference, particularly for general neurologists, internists, family medicine physicians, and neurology residents and nurses who see and treat MS patients.

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Product Details

ISBN-13:
9781936287758
Publisher:
Demos Medical Publishing, LLC
Publication date:
06/15/2013
Pages:
344
Product dimensions:
5.90(w) x 9.70(h) x 0.50(d)

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Meet the Author

Alexander Rae-Grant, MD, FRCP(C), is Staff Neurologist and Director of Multiple Sclerosis Education; Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Foundation, Cleveland, OH.

Robert J. Fox, MS, FAAN, MD, Medical Director; Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Foundation, Cleveland, OH.

Francois Bethoux, MD, Director of Rehabilitation Services; Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic Foundation, Cleveland, OH.

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