Muscle Biopsy: A Practical Approach / Edition 3

Muscle Biopsy: A Practical Approach / Edition 3

by Victor Dubowitz, Caroline A. Sewry
     
 

ISBN-10: 1416025936

ISBN-13: 9781416025931

Pub. Date: 10/16/2006

Publisher: Elsevier Health Sciences

In this book, Professor Victor Dubowitz manages to bridge the gap between clinical syndromes/disorders and their underlying pathologies. An internationally renowned figure in the field of muscle disease, Professor Dubowitz skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment. This reference describes

Overview

In this book, Professor Victor Dubowitz manages to bridge the gap between clinical syndromes/disorders and their underlying pathologies. An internationally renowned figure in the field of muscle disease, Professor Dubowitz skillfully guides you through the complexities of pathologic diagnoses and their implications for clinical treatment. This reference describes the techniques of obtaining a muscle biopsy and examines the histochemical, histological, electron microscopical and molecular appearance of normal muscle and the pathology of individual muscle disease.

• Covers the entire range of diagnostic/investigative techniques, providing you with all of the necessary tools to formulate an accurate diagnosis.
• Offers a combination of clinical and pathological experience for a unique perspective on a complex and difficult area of diagnosis.
• Addresses the "knowledge explosion" over the last 10 years in the fields of molecular genetics and immunocytochemistry, including all of the latest clinically relevant investigative techniques.
• Focuses on diagnostic techniques and on the diagnostic interpretation of results, giving you a portable reference book and a bench book in a single volume.

• Presents all the latest techniques in molecular diagnosis and immunocytochemistry as they apply to individual disorders.
• Includes high-quality, full-color illustrations throughout the book.
• Incorporates tables, summary charts, and boxes to provide a user-friendly, accessible format.

Product Details

ISBN-13:
9781416025931
Publisher:
Elsevier Health Sciences
Publication date:
10/16/2006
Edition description:
New Edition
Pages:
626
Product dimensions:
7.70(w) x 9.80(h) x 1.40(d)

Related Subjects

Table of Contents

Section 1 The Biopsy: Normal and Diseased Muscle

1. The procedure of muscle biopsy

2. Histological and histochemical stains and reactions

3. Normal muscle

4. Definition of pathological changes seen in muscle biopsies

5. Ultrastructural changes in diseased muscle

6. Immunohistochemistry

7. How to read a biopsy

Section 2 Pathological Muscle: Individual Diseases

8. Classification of neuromuscular disorders

9. Neurogenic disorders

10. Muscular dystrophies and allied disorders I: Duchenne and Becker muscular dystrophy

11. Muscular dystrophies and allied disorders II: limb-girdle muscular dystrophies

12. Muscular dystrophies and allied disorders III: congenital muscular dystrophies

13. Muscular dystrophies and allied disorders IV: Emeryƒ{Driefuss muscular dystrophies and Bethlem myopathy

14. Muscular dystrophies and allied disorders V: facioscapulohumeral dystrophy, myotonic dystrophy, oculopharyngeal muscular dystrophy

15. Congenital myopathies

16. Myofibrillar myopathies

17. Metabolic myopathies I: glycogenoses

18. Metabolic myopathies II: lipid related disorders and mitochondrial myopathies

19. Endocrine disorders

20. Ion channel disorders

21. Myasthenic syndromes

22. Inflammatory myopathies

23. Toxic and drug-induced myopathies
Russell Lane, Charing Cross Hospital

Appendix 1. Glossary of commonly used terms

References

Index

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