Muscular Dystrophies: Handbook of Clinical Neurology Vol.101 (Series Editors: Aminoff, Boller and Swaab)

Muscular Dystrophies: Handbook of Clinical Neurology Vol.101 (Series Editors: Aminoff, Boller and Swaab)

by Robert C. Griggs
     
 

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The Handbook of Clinical Neurology Vol 101: Muscular Dystrophies discusses the pathogenesis and treatment prospects for muscular dystrophies. It summarizes the advances in molecular and cell biology, biochemistry, and other biological sciences, with an emphasis on their application to this group of muscle disorders and to their clinical

Overview

The Handbook of Clinical Neurology Vol 101: Muscular Dystrophies discusses the pathogenesis and treatment prospects for muscular dystrophies. It summarizes the advances in molecular and cell biology, biochemistry, and other biological sciences, with an emphasis on their application to this group of muscle disorders and to their clinical implications.

Starting with an overview of muscular dystrophies, the book’s 16 chapters discuss dystrophinopathies; sarcoglycanopathies; congenital muscular dystrophies; collagen VI-related myopathies; limb-girdle muscular dystrophy 2A; dysferlinopathies; limb-girdle muscular dystrophy 2H and the role of TRIM32; and caveolinopathies. The book also covers myofibrillar myopathies; Emery-Dreifuss muscular dystrophy; facioscapulohumeral dystrophy and scapuloperoneal syndromes; oculopharyngeal muscular dystrophy; myotonic dystrophy types 1 and 2; and distal muscular dystrophies.

This book is useful to basic investigators, as it offers an increased understanding of muscular dystrophies; and to clinicians, with its emphasis on issues that are relevant to the care, diagnosis, and management of patients with these disorders.

  • Valuable insights into the muscular dystrophies, including treatment, diagnosis, and care and patient management
  • A comprehensive compilation of the combined wisdom of the most highly regarded physicians, experts, and scientists studying the muscular dystrophies
  • An evaluation of the way advances in molecular and cell biology, biochemistry, and other biological sciences continue to advance the study of these disorders

Editorial Reviews

Doody's Review Service
Reviewer: Ales Hlubocky, MD (Mayo Clinic Arizona)
Description: This succinct and remarkable book on muscular dystrophies reflects the latest expert opinions and a major development in our understanding of these heterogeneous disorders, hopefully laying the foundation for future successful therapies.
Purpose: The purpose is to present a summary of what we know and new insights into these disorders with an emphasis on advances in molecular and cell biology, biochemistry, and other biological sciences and their clinical implications as well as their relevance to the diagnosis and management of patients. These important and worthy objectives are expertly met in this book, part of the Handbook of Clinical Neurology series.
Audience: The editors have assembled an impressive international group of renowned neuromuscular experts to write this book. Although it targets basic investigators and clinicians in general, it will benefit neuromuscular specialists, neurologists, neurology residents, and fellows the most.
Features: Taking into account the dilemma of the ingrained terminology and incompleteness of traditional classifications based on age of onset, mode of inheritance, and pattern of weakness for these disorders, the authors include the nomenclature stemming from the genetic defect such as dystrophinopathies, sarcoglycanopathies, the collagen VI-related myopathies, dysferlinopathies, caveolinopathies, etc. Chapters provide cogent summaries of each of these muscular dystrophy subtypes with sections that highlight a logical approach that includes information not only on background, epidemiology, pathology, pathophysiology, but also the recommended diagnostic algorithms, management, prognosis, and research, along with hopes for future causative therapies. The tables, diagrams, and figures are well designed, easy to understand, and demonstrate the take-home message with clarity. Although some illustrations are in color, there is room for more of these as they significantly liven up the text and enhance readers' experience.
Assessment: This is a high quality resource for the targeted audience that pays special attention to rapid developments and the latest information in the field of neuromuscular neurology while providing a practical approach to the diagnosis and management of these disorders. It competes well with other books on this topic and, in some areas, surpasses them.

Product Details

ISBN-13:
9780080450315
Publisher:
Elsevier Science
Publication date:
07/11/2011
Series:
Handbook of Clinical Neurology Series , #101
Pages:
284
Product dimensions:
7.50(w) x 10.40(h) x 0.80(d)

Related Subjects

Meet the Author

Dr. Michael J. Aminoff is an internationally recognized, board-certified neurologist and clinical neurophysiologist who works at UCSF Medical Center and specializes in Parkinson's disease and other movement disorders, holding an endowed chair in Parkinson’s disease research. Aminoff was educated in England, graduating with honors from University College in London in 1962 and as a physician from University College Hospital Medical School in 1965. He completed postdoctoral training in various London teaching hospitals, but especially at the National Hospital for Neurology and Neurosurgery in Queen Square, London, and at its affiliated Institute of Neurology, where his research on spinal physiology gained him an MD degree (an advanced research thesis in the UK). He joined UCSF Medical Center in 1974, becoming a full professor in 1982; the title of distinguished professor was conferred on him in 2010. In 2000, he was awarded a doctorate in science (an advanced doctorate in the Faculty of Science) from the University of London. He has received numerous awards including the Lifetime Achievement Award from the American Association of Neuromuscular & Electrodiagnostic Medicine (2006) and the A.B.Baker Award from the American Academy of Neurology (2007). He was the editor-in-chief of Muscle and Nerve, a major neuroscience journal for 10 years; serves on the editorial boards of several other medical and scientific journals; and has authored nearly 250 research publications as well as numerous books. Dr. Aminoff is also editor-in-chief of the Encyclopedia of Neurological Sciences and series editor of the multivolume Handbook of Clinical Neurology (Elsevier).

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