- Shopping Bag ( 0 items )
Doody's Review ServiceReviewer: Daniel B. Hier, MD (University of Illinois at Chicago College of Medicine)
Description: This book, part of the Methods in Molecular Medicine series that provides detailed methods and procedures for molecular testing in a variety of genetically determined diseases, deals with molecular testing in muscular dystrophy.
Purpose: Like other volumes in the series, this book seeks to provide laboratory scientists and clinicians with enough detail on molecular testing to be able to duplicate or modify these published methods in their laboratories.
Audience: This book will be of primary interest to pathologists, geneticists, and neurologists actively engaged in molecular testing of the patients with muscular dystrophy.
Features: This is a multiauthored collection of 25 reviews that are procedure-based. Each review details methods, materials, and equipment used in the molecular testing as well as typical results and test standardization. This is a highly practical book aimed at scientists actively engaged in doing the molecular tests. Diseases covered include the X-linked muscular dystrophies and the autosomal recessive muscular dystrophies. Both DNA and protein methods are covered. Concluding chapters discuss gene therapy and animal models of muscular dystrophy.
Assessment: This is a collection of detailed protocols for molecular testing of muscular dystrophy. Reagents, materials, equipment, methods, and results are carefully detailed and explained.