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Doody's Review ServiceReviewer: John F. Moran, MD (Loyola University Stritch School of Medicine)
Description: This is a multiauthored text on the detection of viable myocardium that may be stunned or hibernating and responsive to revascularization.
Purpose: The purpose is to bring basic cellular physiology and clinical decision making together in a focus on myocardial viability. The editor and contributors succeed in their objectives.
Audience: The book is directed to the clinician scientist and all students of physiology and metabolism whether they are radiologists or cardiologists. There is much good information here to do background for research projects in this area.
Features: The monograph contains 18 chapters divided into five areas. Each chapter comes with an extensive list of references. Ischemic cellular physiology, clinical issues, and diagnostics are well discussed. Echo, SPECT, PET, and MRI scanning techniques are all covered well. From a basic science viewpoint, the ischemic effects of nitric oxide, cellular energy cycles, and cellular channels are discussed. There is a particularly good section on thallium and myoview scans.
Assessment: With this monograph the editor brings much information on myocardial viability together into one place. The basic and clinical aspects of stunned and hibernating myocardium are important to clinical decision making about revascularization. These are important clinical topics and all the answers are not available. This text is a good start for interested professionals.