Name Reactions of Functional Group Transformations / Edition 1

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This practical, well-organized reference delves deeply into functional group transformations, to provide all the detailed information that researchers need.

  • Topics are organized into the following sections: oxidation, reduction, asymmetric synthesis, and functional group manipulations
  • Each section includes a description of the functional group transformation, the historical perspective, mechanisms, variations and improvements on the reaction, synthetic utilities and applications for the reaction, experimental details, and references to the primary literature
  • Contributors are well-known and respected for their work on the specific name reactions.
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Editorial Reviews

From the Publisher
"Unlike many previous books on name reactions, which present manyreactions but treat them superficially, this book provides anexcellent selection of useful name reactions, which have been givenin depth, well-illustrated, instructional, and well-referencedaccounts." (Journal of Medicinal Chemistry, February 2008)

"Helps you explore how you think, communicate and react,allowing you to change your behaviours and become a more expertprofessional practitioner." (Journal of PerioperativePractice, April 2008)

"Reading this book has been enjoyable experience. Again andagain, one comes across surprising reaction possibilities ofwell-known reagents, or some lesser known variants of commontransformations." (Angewandte Chemie)

"This book provides an excellent selection of useful namereactions, which have been given in depth, well-illustrated,instructional, and well-referenced accounts." (Journal ofMedicinal Chemistry, January 11, 2008)

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Product Details

  • ISBN-13: 9780471748687
  • Publisher: Wiley
  • Publication date: 7/16/2007
  • Series: Comprehensive Name Reactions Series , #1
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 768
  • Product dimensions: 7.81 (w) x 9.51 (h) x 1.72 (d)

Meet the Author

Jie Jack Li is a medicinal chemist at Pfizer Global Researchand Development in Ann Arbor, Michigan. He is coauthor ofContemporary Drug Synthesis and editor of Name Reactionsin Heterocyclic Chemistry (both from Wiley).

E. J. Corey, Professor Emeritus at Harvard University, isscientific editorial advisor for this book. Dr. Corey won the NobelPrize in Chemistry in 1990 for his development of the theory andmethodology of organic synthesis, and was awarded the PriestleyMedal in 2004.

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Table of Contents



Contributing Authors.

Chapter 1. Asymmetric Synthesis.

Chapter 2. Reduction.

Chapter 3. Oxidation.

Chapter 4. Olefination.

Chapter 5. Amine Synthesis.

Chapter 6. Carboxylic Acid Derivatives Synthesis.

Chapter 7. Miscellaneous Functional Group Manipulations.


Appendix 1. Table of Contents for Volume 1: Name Reactions inHeterocyclic Chemistry.

Appendix 2. Table of Contents for Volume 3: Name Reactionsfor Chain Extension.

Appendix 3. Table of Contents for Volume 4: Name Reactionsfor Ring Formation.

Appendix 4. Table of Contents for Volume 5: Name Reactions inHeterocyclic Chemistry-2.

Subject Index.

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