Human Genetics: Problems and Approaches

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1979 Hardcover 1st Edition Good Springer 1979 1st Edition Edgewear to boards, pos penned inside cover and on inside page edge, clean tight bright unmarked text. Review"...should ... be essential reading for all geneticists. Reading the contents alone sparked a sense of anticipation that made this essential bedtime reading! ...-there's nothing boring here." Heredity"...a classic textbook and compendium of information. It is, therefore, a distinct pleasure to open the third edition..." Trends in Genetics--This text refers to the Hardcover edition. Product DescriptionInstitut fur Humangenetik und Anthropologie, Heidelberg, Germany. Third edition of an extensive textbook on the concepts and problems of human and medical genetics, for geneticists, biomedical researchers, physicians, and epidemiologists. Previous edition 1986. Emphasizes molecular concepts and techniques. --This text refers to the Hardcover edition. Read more Show Less

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Overview

The third edition of Vogel and Motulskys classic presents a cohesive and up-to-date compendium of the concepts, results, and problems underlying theory and practice in human medical genetics. In addition to important information on the molecular basis of human genetics, the book describes the principles of other epigenetic processes that together create the phenotype of a human being.

The book contains black-and-white, two-color, and full-color illustrations.

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Editorial Reviews

Teresa A. Hadro
The 3rd edition of Vogel and Motulsky's Human Genetics: Problems and Approaches is a welcome updating of a classic much-appreciated by those interested in the history and philosophy of human genetics as well as the facts, technologies and applications of their science. This book is a first text in human genetics which presents its subject in an explicit conceptual framework designed to encourage critical thinking on the part of its readers. The authors state that they hope to avoid the distortions that arise when textbooks are written as if science had grown in a "simple, cumulative manner." Throughout the text, human genetics is considered as both a basic and an applied science. By exploring, rather than ignoring, the frequent contradictions and wonderful synergisms resulting from this "split personality" the authors achieve their purpose. Their textbook is unlike any other in the field, and makes fascinating reading not only for the college students who form the primary audience, but also for practitioners of genetics who love their science. The text is readable, current, and instructive; the illustrations appropriate and informative. Some, especially the color photos of fluorescent in-situ hybridization (FISH) are outstanding. The table of contents is so exhaustive the authors found it necessary to create a shorter "contents overview." The appendices provide easy access to often referenced biometric tools and systems of nomenclature. This book lends itself more to discussion than to lecture and represents a rare approach to the teaching of the most intimate of human sciences. Interesting facts and questions are presented alongside discussions of basicinformation, technologies and applications. The sheer breadth of the material presented will challenge students who use it. The uncommon depth of the material will provoke thought and, perhaps, original thinking among those who read it.
Doody's Review Service
Reviewer: Teresa A. Hadro, MS (Children's Memorial Hospital)
Description: The 3rd edition of Vogel and Motulsky's Human Genetics: Problems and Approaches is a welcome updating of a classic much-appreciated by those interested in the history and philosophy of human genetics as well as the facts, technologies and applications of their science.
Purpose: This book is a first text in human genetics which presents its subject in an explicit conceptual framework designed to encourage critical thinking on the part of its readers. The authors state that they hope to avoid the distortions that arise when textbooks are written as if science had grown in a "simple, cumulative manner." Throughout the text, human genetics is considered as both a basic and an applied science. By exploring, rather than ignoring, the frequent contradictions and wonderful synergisms resulting from this "split personality" the authors achieve their purpose.
Audience: Their textbook is unlike any other in the field, and makes fascinating reading not only for the college students who form the primary audience, but also for practitioners of genetics who love their science.
Features: The text is readable, current, and instructive; the illustrations appropriate and informative. Some, especially the color photos of fluorescent in-situ hybridization (FISH) are outstanding. The table of contents is so exhaustive the authors found it necessary to create a shorter "contents overview." The appendices provide easy access to often referenced biometric tools and systems of nomenclature.
Assessment: This book lends itself more to discussion than to lecture and represents a rare approach to the teaching of the most intimate of human sciences. Interesting facts and questions are presented alongside discussions of basic information, technologies and applications. The sheer breadth of the material presented will challenge students who use it. The uncommon depth of the material will provoke thought and, perhaps, original thinking among those who read it.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780387094595
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 6/28/1982
  • Pages: 700

Table of Contents

1 History of Human Genetics 11
2 The Human Genome: Chromosomes 25
3 The Human Genome: Genes and DNA 83
4 Formal Genetics of Humans: Modes of inheritance 129
5 Formal Genetics of Humans: Linkage Analysis and Gene Clusters 163
6 Formal Genetics of Humans: Multifactorial Inheritance and Common Diseases 195
7 Gene Action: Genetic Diseases 257
8 Gene Action: Developmental Genetics 361
9 Mutation: Spontaneous Mutation in Germ Cells 385
10 Mutation: Somatic Mutation, Cancer, and Aging 431
11 Mutation: Induction by Ionizing Radiation and Chemicals 457
12 Population Genetics: Description and Dynamics 495
13 Population Genetics: Consanguinity, Genetic Drift 549
14 Human Evolution 583
15 Behavioral Genetics: Research Strategies and Examples 623
16 Behavioral Genetics: Affective Disorders and Schizophrenia 693
17 Behavioral Genetics: Differences Between Populations 705
18 Genetic Counseling and Prenatal Diagnosis 711
19 Genetic Manipulations and the Biological Future of the Human Species 733
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