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Natural Products Isolation / Edition 2
     

Natural Products Isolation / Edition 2

by Satya D. Sarker
 

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ISBN-10: 1617375756

ISBN-13: 9781617375750

Pub. Date: 11/19/2010

Publisher: Springer-Verlag New York, LLC

The term “natural products” spans an extremely large and diverse range of chemical compounds derived and isolated from biological sources. Our interest in natural products can be traced back thousands of years for their usefulness to humankind, and this continues to the present day. Compounds and extracts derived from the biosphere have found uses in

Overview

The term “natural products” spans an extremely large and diverse range of chemical compounds derived and isolated from biological sources. Our interest in natural products can be traced back thousands of years for their usefulness to humankind, and this continues to the present day. Compounds and extracts derived from the biosphere have found uses in medicine, agriculture, cosmetics, and food in ancient and modern societies around the world. Therefore, the ability to access natural products, understand their usefulness, and derive applications has been a major driving force in the field of natural product research. The first edition of Natural Products Isolation provided readers for the first time with some practical guidance in the process of extraction and isolation of natural products and was the result of Richard Cannell’s unique vision and tireless efforts. Unfortunately, Richard Cannell died in 1999 soon after completing the first edition. We are indebted to him and hope this new edition pays adequate tribute to his excellent work. The first edition laid down the “ground rules” and established the techniques available at the time. Since its publication in 1998, there have been significant developments in some areas in natural product isolation. To capture these developments, publication of a second edition is long overdue, and we believe it brings the work up to date while still covering many basic techniques known to save time and effort, and capable of results equivalent to those from more recent and expensive techniques.

Product Details

ISBN-13:
9781617375750
Publisher:
Springer-Verlag New York, LLC
Publication date:
11/19/2010
Series:
Methods in Biotechnology Series , #20
Edition description:
Softcover reprint of hardcover 2nd ed. 2005
Pages:
516
Product dimensions:
5.98(w) x 9.02(h) x 0.05(d)

Table of Contents

Natural Product Isolation: An Overview
Satyajit D. Sarker, Zahid Latif, and Alexander I. Gray

Initial and Bulk Extraction
Véronique Seidel

Supercritical Fluid Extraction
Lutfun Nahar and Satyajit D. Sarker

An Introduction to Planar Chromatography
Simon Gibbons

Isolation of Natural Products by Low-Pressure Column Chromatography
Raymond G. Reid and Satyajit D. Sarker

Isolation by Ion-Exchange Methods
David G. Durham

Separation by High-Speed Countercurrent Chromatography
James B. McAlpine and Patrick Morris

Isolation by Preparative High-Performance Liquid Chromatography
Zahid Latif

Hyphenated Techniques
Satyajit D. Sarker and Lutfun Nahar

Purification by Solvent Extraction Using Partition Coefficient
Hideaki Otsuka

Crystallization in Final Stages of Purification
Alastair J. Florence, Norman Shankland, and Andrea Johnston

Dereplication and Partial Identification of Compounds
Laurence Dinan

Extraction of Plant Secondary Metabolites
William P. Jones and A. Douglas Kinghorn

Isolation of Marine Natural Products

Wael E. Houssen and Marcel Jaspars

Isolation of Microbial Natural Products
Russell A. Barrow

Purification of Water-Soluble Natural Products
Yuzuru Shimizu and Bo Li

Scale-Up of Natural Product Isolation
Steven M. Martin, David A. Kau, and Stephen K. Wrigley

Follow-Up of Natural Product Isolation
Richard J. P. Cannell

Index

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