Nerve-Muscle Interaction / Edition 2

Nerve-Muscle Interaction / Edition 2

by Gerta Vrbova, Tessa Gordon, Rosie Jones
     
 

ISBN-10: 0412404907

ISBN-13: 9780412404900

Pub. Date: 12/31/1994

Publisher: Springer Netherlands

In the second century, Galen recognized that nerve and muscle were functionally inseparable since contraction of muscle occurred only if the nerves supplying that muscle were intact. He therefore concluded that the shortening of a muscle was controlled by the central nervous sytem while the extension of a muscle could occur in the absence of innervation. Nerves, he

Overview

In the second century, Galen recognized that nerve and muscle were functionally inseparable since contraction of muscle occurred only if the nerves supplying that muscle were intact. He therefore concluded that the shortening of a muscle was controlled by the central nervous sytem while the extension of a muscle could occur in the absence of innervation. Nerves, he thought, were the means of transport for animal spirits to the muscles; the way in which animal spirits may bring about contraction dominated the study of muscle physiology from that time until the historical discovery of Galvani that muscle could be stimulated electrically and that nerve and muscle were themselves a source of electrical energy. It is now well known that nerves conduct electrically and that transmission from nerve to striated muscle is mediated by the chemical which is liberated from nerve terminals onto the muscle membrane. In vertebrates this chemical is acetylcholine (ACh). Thus the concept of spirits that are released from nerves and control muscle contraction directly, is no longer tenable. Nevertheless the concept of 'substances' transported down nerv~s which directly control many aspects of muscle has not been abandoned, and has in fact been frequently reinvoked to account for the long-term regula­ tion of many characteristics of muscle (see review by Gutmann, 1976) and for the maintenance of its structural integrity.

Product Details

ISBN-13:
9780412404900
Publisher:
Springer Netherlands
Publication date:
12/31/1994
Edition description:
2nd ed. 1994
Pages:
256
Product dimensions:
6.10(w) x 9.25(h) x 0.36(d)
Age Range:
18 Years

Table of Contents

Preface to the second edition. Preface to first edition. Acknowledgements. 1. Early development of muscle. 2. Development of motoneurones. 3. Encounter of motor nerves with muscle fibres. 4. Tonic and phasic mucle fibres of lower vertebrates and birds. 5. Mammalian muscles and motor units. 6. Emergence of the mammalian motor unit. 7. Plasticity of muscles and their motor units. 8. Axotomy: effects on motoneurones, nerves and muscles. 9. Nerve regeneration and muscle reinnervation. 10. Disturbances of nerve-muscle interactions and their consequences. Index.

Customer Reviews

Average Review:

Write a Review

and post it to your social network

     

Most Helpful Customer Reviews

See all customer reviews >