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Gert Ter Horst and a panel of recognized experts illuminate the complexities and importance of heart-brain and brain-heart interactions in human health. These distinguished authorities critically review what is known about autonomic control of the heart, hypothalamo-pituitary- adrenal modulation, heart pain, modulation by humoral factors, and the relationship between cognitive/neuropsychiatric disorders and heart disease. Highly relevant and up-to-date, The Nervous System and the Heart offers the first comprehensive treatment of the important mutual interactions of the heart and the brain. By integrating specialist knowledge in cardiology with that from neuroscience, this important book constitutes a brilliant guide to today's novel approaches to neural control of the heart and consequent reduction of cardiovascular mortality.
The book contains black-and-white illustrations.
The heart and the brain have a bilateral physiological dependence so that they can both function properly. A consequence of this close relationship is that dysfunction in either organ will affect the other, which is apparent in the common coexistence of neuropathological and cardiovascular diseases. This book brings together a distinguished panel of authors who review various aspects of heart-brain interaction such as neuronal control, cardiac nociceptive mechanisms, and the nervous and humoral feedback systems. Its aim is to give a concise overview of all of the important heart-brain interaction mechanisms to a broad audience, ranging from the post-graduate level to specialized areas of experimental cardiology, psychiatry, pharmacology, and neurobiology.
Part I. Autonomic Control Nerve Supply of the Heart, Simon J. Crick, Mary N. Sheppard, and Robert H. Anderson. Emotions and Heart Activity Control: Neurocircuitries and Pathway Interactions, Gert J. Ter Horst. Circadian Organization of the Autonomic Nervous System, Ruud M. Buijs, Michael L. H. J. Hermes, Jaipei Dai, Frank Scheer, and Andries Kalsbeek. Neuropathology and Cardiovascular Regulation: Fundamental Aspects, David F. Cechetto. Neuropathology and Cardiovascular Regulation: Clinical Aspects, Vilho V. Myllyllä, Juha T. Korpelainen, Uolevi Tolonen, Hannele Havanka, and Anne Saari. Part II. The Hypothalamo-Pituitary-Adrenal System and the Heart Stress, the Hypothalamo-Pituitary-Adrenal System, and the Heart, Béla Bohus and S. Michiel Korte. Part III. Heart Pain Cardiac Nociceptive Systems, Björn E. Eriksson and Christer Sylvén. The Neuroanatomy of Cardiac Nociceptive Pathways: Differential Representations of 'Deep' and 'Superficial' Pain, Kevin A. Keay, Colin I. Clement, and Richard Bandler. Neurophysiology of Heart Pain, Robert D. Foreman. Neuroimaging of Heart Pain, Stuart D. Rosen. Part IV Humoral Factors The Central Renin-Angiotensin System in Cardiovascular Regulation, Lawrence P. Reagan. Mediators of Inflammation in Patients with Coronary Artery Disease, Mike J. L. DeJongste and Gert J. Ter Horst. Part V. Heart Disease and Brain Dysfunction Heart Disease and Cognitive/Neuropsychiatric Disorders, Dorien M. Tulner and Hans A. Den Boer. Index.