Neural Plasticity and Cognitive Development: Insights from Children with Perinatal Brain Injury

Overview

The advent of modern neurobiological methods over the last three decades has provided overwhelming evidence that it is the interaction of genetic factors and the experience of the individual that guides and supports brain development. Brains do not develop normally in the absence of critical genetic signaling, and they do not develop normally in the absence of essential environmental input. The key to understanding the origins and emergence of both the brain and behavior lies in understanding how inherited and ...

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Overview

The advent of modern neurobiological methods over the last three decades has provided overwhelming evidence that it is the interaction of genetic factors and the experience of the individual that guides and supports brain development. Brains do not develop normally in the absence of critical genetic signaling, and they do not develop normally in the absence of essential environmental input. The key to understanding the origins and emergence of both the brain and behavior lies in understanding how inherited and environmental factors are engaged in the dynamic and interactive processes that define and direct development of the neurobehavioral system.

Neural Plasticity and Cognitive Development focuses on children who suffered focal brain insult (typically stroke) in the pre- or perinatal period which provides a model for exploring the dynamic nature of early brain and cognitive development. In most, though not all, of the cases considered, the injuries affect substantial portions of one cerebral hemisphere, resulting in patterns of neural damage that would compromise cognitive ability in adults. However, longitudinal behavioral studies of this population of children have revealed only mild cognitive deficits, and preliminary data from functional brain imaging studies suggest that alternative patterns of functional organization emerge in the wake of early injury. Neural Plasticity and Cognitive Development posits that the capacity for adaptation is not the result of early insult. Rather, it reflects normal developmental processes which are both dynamic and adaptive operating against a backdrop of serious perturbation of the neural substrate.

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Product Details

  • ISBN-13: 9780195389944
  • Publisher: Oxford University Press
  • Publication date: 5/29/2012
  • Pages: 384
  • Product dimensions: 6.40 (w) x 9.30 (h) x 0.90 (d)

Meet the Author

Joan Stiles, PhD
Emeritus Professor of Cognitive Sciences
University of California, San Diego
La Jolla, CA

Judy S. Reilly, PhD
Emeritus Professor of Psychology
San Diego State University
San Diego, CA

Susan C. Levine, PhD
Stella M. Rowley Professor
Departments of Psychology, Comparative Human Development, and Committee on Education;
Chair
Department of Psychology
University of Chicago
Chicago, IL

Doris A. Trauner, MD
Professor of Neurosciences and Pediatrics
University of California, San Diego School of Medicine
La Jolla, CA;
Chief
Pediatric Neurology
University of California, San Diego School of Medicine and Rady Children's Hospital San Diego
San Diego, CA

Ruth Nass, MD
Professor of Child Neurology, Child and Adolescent Psychiatry, and Pediatrics
New York University School of Medicine
New York, NY

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Table of Contents

PREFACE

PART 1: NEUROBIOLOGY

CHAPTER 1: Neuroplasticity and the Developing Brain

CHAPTER 2: The Basics of Brain Development

CHAPTER 3: Etiology and Neurological Effects of Perinatal Stroke

PART 2: BEHAVIORAL STUDIES

CHAPTER 4: Somatosensory and Motor Processes

CHAPTER 5: Visuospatial Processes

CHAPTER 6: Attention, Memory and Executive Functions

CHAPTER 7: Early Communicative Development to First Words

CHAPTER 8: Later Language Development: Syntax and Discourse

CHAPTER 9: Plasticity of Overall Intellectual Functioning: Evidence from Standardized Tests

PART 3: CLINICAL AND THEORETICAL IMPLICATIONS

CHAPTER 10: Clinical Implications

CHAPTER 11: Toward and Integrative Model of Neurobehavioral Development

Index

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