Neural Stem Cells: Development and Transplantation / Edition 1

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This volume will be particularly useful for students, basic scientists, and clinicians in the academic or industrial sectors who have an interest in understanding neural development and its application to repairing the nervous system.
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Editorial Reviews

Doody's Review Service
Reviewer: Celso Agner, MD, MS, MSc (Michigan Neurology Partners)
Description: Stem cell research has been influencing the development of neuroscience ever since its discovery, in particular for the possible use of stem cells in the management of degenerative diseases of the nervous system. A book on its applications is very welcome in the field.
Purpose: The purpose of this book is to address the development of stem cells and the current potential application for the treatment of neurological conditions. These worthy objectives are fully met by the authors.
Audience: Neurologists and neurosurgeons are the main audiences for this book.
Features: The most important aspect of this book is the progression of topics from identification of stem cells in different areas of the body to the potential transplantation for the management of degenerative diseases such as Parkinson's and others. The illustrations are well done and correlate well with the written text. In my view, one of the major shortcomings is the absence of sections related to the survival of stem cells in the host organ and the current possibility of clinical applications. Overall, however, the book is of very good quality.
Assessment: This is an important book for neurologists, neurosurgeons, and neurophysiologists interested in the study and applications of stem cells in health and disease.

3 Stars from Doody
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Product Details

  • ISBN-13: 9781402075889
  • Publisher: Springer US
  • Publication date: 11/28/2003
  • Edition description: 2004
  • Edition number: 1
  • Pages: 473
  • Product dimensions: 6.40 (w) x 9.50 (h) x 1.30 (d)

Table of Contents

List of Contributors
Ch. 1 Neural Stem Cell Models of Development and Disease 1
Ch. 2 Neural Stem and Progenitor Cells: Lineage and Cell Fate Determination 55
Ch. 3 Stage-Specific and Cell Fate Markers 95
Ch. 4 Isolation of Stem Cells from Multiple Sites in the CNS 127
Ch. 5 Neural Cells Derived From Embryonic Stem Cells 155
Ch. 6 On the Origin of Newly Made Neural Cells in the Adult Organism: Does Transdifferentiation Occur? 181
Ch. 7 Neural Stem Cell Purification and Clonal Analysis 207
Ch. 8 Embryonic and Neural Stem Cell Lines 231
Ch. 9 Isolation, Survival, Proliferation, and Differentiation of Human Neural Stem Cells 271
Ch. 10 Neural Replacement by Transplantation 299
Ch. 11 Derivation of Myelin-forming Cells for Transplantation Repair of the CNS 329
Ch. 12 Induction of Adult Cortical Neurogenesis From Neural Precursors In Situ 355
Ch. 13 Neural Stem Cells for Cellular Therapy in Humans 379
Ch. 14 Genetic Modification of Neural Stem/Progenitor Cells 413
Index 447
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