Neurobehavioral Anatomy / Edition 3

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Thoroughly revised and updated to reflect key advances in behavioral neurology, Neurobehavioral Anatomy, Third Edition is a clinically based account of the neuroanatomy of human behavior centered on a consideration of behavioral dysfunction caused by disorders of the brain. A concise introduction to brain-behavior relationships that enhances patient care and assists medical students, the book also serves as a handy reference to researchers, neuroscientists, psychiatrists, and geriatricians.

The book outlines how cognitive and emotional functions are represented and organized in the brain to produce the behaviors regarded as uniquely human. It reviews the effects of focal and diffuse brain lesions, and from this analysis a conception of the normal operations of the healthy brain emerges. Christopher M. Filley integrates data and material from different disciplines to create a concise and accessible synthesis that informs the clinical understanding of brain-behavior relationships. Clinically practical and theoretically stimulating, the book is an invaluable resource for those involved in the clinical care and study of people with neurobehavioral disorders.

Including a useful glossary and extensive references guiding users to further research, the third edition will be of significance to medical students, residents, fellows, practicing physicians, and the general reader interested in neurology.

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Editorial Reviews

Filley (neurology and psychiatry, U. of Colorado School of Medicine) introduces the organizational basis of human behavior within the structure of the human brain from the viewpoint of behavioral neurology. He outlines how cognitive and emotional functions are represented in the brain to produce human behavior, gives a general overview of brain- behavior relationships, and reviews the effects of brain lesions and the workings of various disorders. For researchers and students, and interested general readers. Includes a glossary and b&w diagrams. Annotation c. Book News, Inc., Portland, OR (
Doody's Review Service
Reviewer: Cristina Orfei, MD (University of Illinois at Chicago)
Description: This is an updated and concise review of the correlation between neuroanatomy and behavior. In only 227 pages, this well-referenced book covers the different manifestations of aphasias, agnosias, acute confusional states, dementias, and traumatic brain injury and presents an in-depth discussion of the different frontal lobe syndromes. The first edition was published in 1995.
Purpose: The purpose is to address the large audience of students and clinical practitioners who have an interest in the function of the brain and its clinical manifestations. It is simply worded and well written, meeting the purpose of a quick review with several up-to-date references, and fulfilling the author's objective of explaining in simple terms a complex scenario.
Audience: The author's expertise in behavioral neurology and its clinical aspects makes this book a useful addition to the library of every student of neurology and psychiatry and clinical psychologists. The mature clinician will enjoy the discussion of the evolution of functional neuroimaging, new theory in traumatic brain injury, and the genetic abnormalities of dementia, Alzheimer's type.
Features: The reader will learn the complex interactions of subcortical structures in the disturbance of arousal, the differential diagnosis of acute confusional state, and the perplexing definition of consciousness where neuronal activity is transformed into subjective conscious experience. The description of the case of Phineas Gage in the discussion of frontal lobe syndromes exemplifies the role of the orbitofrontal cortex in disinhibition and distractibility. The medial frontal and dorsolateral syndromes have different characteristics with apathy, mutism, or transcortical motor aphasia, paresis of lower limbs, and perseveration and impairment of executive functions. The concept of higher cerebral vs. high cortical functions is addressed in chapter 12 on the dementias, documenting the importance of the subcortical structures (thalamus, basal ganglia, and cerebral white matter) as participants in the neuronal network that serve specific higher functions. The importance of genetic inheritance in Alzheimer's disease is identified in abnormalities of chromosome 14, 19, and 21 in five percent of Alzheimer's patients, while the role of synaptic loss is emphasized more than amyloid deposition in the pathogenesis of this condition.
Assessment: This book, with its simple format and clarity of exposition, will open the door on the complexity of human behavior to a large audience.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781607320982
  • Publisher: University Press of Colorado
  • Publication date: 3/16/2011
  • Edition number: 3
  • Pages: 304
  • Sales rank: 455,827
  • Product dimensions: 6.00 (w) x 8.90 (h) x 0.70 (d)

Meet the Author

Christopher M. Filley, M.D., is Director of the Behavioral Neurology Section and Professor of Neurology and Psychiatry at the University of Colorado School of Medicine. He is also Attending Neurologist at the Denver Veterans Affairs Medical Center.

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Table of Contents

Preface to the Third Edition XI

Chapter 1 Behavior and the Brain 1

The Mind-Brain Problem 2

General Features of Brain Anatomy 5

The Excesses of Phrenology 13

Behavioral Neurology 14

References 21

Chapter 2 Mental Status Evaluation 25

History and Interview 25

Mental Status Examination 28

Standardized Mental Status Testing 40

References 44

Chapter 3 Disorders of Arousal and Attention 49

Arousal Dysfunction 51

Attentional Dysfunction 54

References 60

Chapter 4 Memory Disorders 63

Inattention 64

Amnesia 65

Remote Memory Loss 71

References 72

Chapter 5 Language Disorders 75

Cerebral Dominance and Handedness 78

Aphasia 80

Alexia 86

Agraphia 89

References 90

Chapter 6 Apraxia 95

Limb Kinetic Apraxia 97

Ideomotor Apraxia 97

Ideational Apraxia 101

References 102

Chapter 7 Agnosia 105

Visual Agnosia 107

Auditory Agnosia 112

Tactile Agnosia 113

References 114

Chapter 8 Right Hemisphere Syndromes 119

Constructional Apraxia 120

Neglect 121

Spatial Disorientation 124

Dressing Apraxia 124

Aprosody 125

Amusia 127

Emotional Disorders 129

References 134

Chapter 9 Temporal Lobe Syndromes 139

The Limbic System 140

Temporal Lobe Epilepsy 143

Psychosis in Temporal Lobe Epilepsy 147

Temporal Lobe Epilepsy Personality 150

References 155

Chapter 10 Frontal Lobe Syndromes 159

Orbitofrontal Syndrome 163

Dorsolateral Syndrome 166

Medial Frontal Syndrome 167

Functions of the Frontal Lobes 168

References 172

Chapter 11 Traumatic Brain Injury 175

Focal Lesions 176

Diffuse Lesions 178

References 185

Chapter 12 Dementia 189

Cortical Dementias 194

Subcortical Dementias 200

White Matter Dementias 205

Mixed Dementias 214

References 218

Epilogue 227

Glossary of Neurobehavioral Terms 229

Index 241

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