Neurobehavioral Anatomy / Edition 2

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In Neurobehavioral Anatomy, Christopher M. Filley provides a timely introduction to the organization of human behavior within the structure of the human brain. Writing from the viewpoint of behavioral neurology, the author draws upon a wealth of neurobehavioral knowledge to outline how cognitive and emotional functions are represented in the brain to produce the many behaviors regarded as uniquely human. The effects of focal and diffuse brain lesions are reviewed, and from this analysis emerges a conception of the normal operations of the brain in health. This relatively compact volume, intended more as introductory than comprehensive, will prove useful to those who care for individuals afflicted with brain disorders disrupting normal behavior, to researchers, and to anyone intrigued with the neuroanatomic basis of singularly human capacities. Clinically practical and theoretically stimulating, this book demonstrates that the understanding of the mind must consider the anatomy of the brain.
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Editorial Reviews

Doody's Review Service
Reviewer: Cristina Orfei, MD (University of Illinois at Chicago)
Description: This is an updated and concise review of the correlation between neuroanatomy and behavior. In only 227 pages, this well-referenced book covers the different manifestations of aphasias, agnosias, acute confusional states, dementias, and traumatic brain injury and presents an in-depth discussion of the different frontal lobe syndromes. The first edition was published in 1995.
Purpose: The purpose is to address the large audience of students and clinical practitioners who have an interest in the function of the brain and its clinical manifestations. It is simply worded and well written, meeting the purpose of a quick review with several up-to-date references, and fulfilling the author's objective of explaining in simple terms a complex scenario.
Audience: The author's expertise in behavioral neurology and its clinical aspects makes this book a useful addition to the library of every student of neurology and psychiatry and clinical psychologists. The mature clinician will enjoy the discussion of the evolution of functional neuroimaging, new theory in traumatic brain injury, and the genetic abnormalities of dementia, Alzheimer's type.
Features: The reader will learn the complex interactions of subcortical structures in the disturbance of arousal, the differential diagnosis of acute confusional state, and the perplexing definition of consciousness where neuronal activity is transformed into subjective conscious experience. The description of the case of Phineas Gage in the discussion of frontal lobe syndromes exemplifies the role of the orbitofrontal cortex in disinhibition and distractibility. The medial frontal and dorsolateral syndromes have different characteristics with apathy, mutism, or transcortical motor aphasia, paresis of lower limbs, and perseveration and impairment of executive functions. The concept of higher cerebral vs. high cortical functions is addressed in chapter 12 on the dementias, documenting the importance of the subcortical structures (thalamus, basal ganglia, and cerebral white matter) as participants in the neuronal network that serve specific higher functions. The importance of genetic inheritance in Alzheimer's disease is identified in abnormalities of chromosome 14, 19, and 21 in five percent of Alzheimer's patients, while the role of synaptic loss is emphasized more than amyloid deposition in the pathogenesis of this condition.
Assessment: This book, with its simple format and clarity of exposition, will open the door on the complexity of human behavior to a large audience.
Filley (neurology and psychiatry, U. of Colorado School of Medicine) introduces the organizational basis of human behavior within the structure of the human brain from the viewpoint of behavioral neurology. He outlines how cognitive and emotional functions are represented in the brain to produce human behavior, gives a general overview of brain- behavior relationships, and reviews the effects of brain lesions and the workings of various disorders. For researchers and students, and interested general readers. Includes a glossary and b&w diagrams. Annotation c. Book News, Inc., Portland, OR (

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780870816192
  • Publisher: Univeristy Press of Colorado
  • Publication date: 4/28/2001
  • Edition description: Subsequent
  • Edition number: 2
  • Pages: 228
  • Product dimensions: 5.90 (w) x 9.10 (h) x 0.80 (d)

Meet the Author

Christopher M. Filley, M.D., is Director of the Behavioral Neurology Section and Professor of Neurology and Psychiatry at the University of Colorado School of Medicine. He is also Attending Neurologist at the Denver Veterans Affairs Medical Center.

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Table of Contents

Preface to the First Edition
1 Behavior and the Brain 1
The Mind-Brain Problem 1
General Aspects of Brain Anatomy 4
The Excesses of Phrenology 12
Behavioral Neurology 13
2 Mental Status Evaluation 21
History and Interview 21
Mental Status Examination 23
Standardized Mental Status Testing 33
3 Disorders of Arousal and Attention 39
Arousal Dysfunction 40
Attentional Dysfunction 43
References 49
4 Memory Disorders 53
Inattention 53
Amnesia 54
Remote Memory Loss 61
5 Language Disorders 65
Cerebral Dominance and Handedness 67
Aphasia 70
Alexia 75
Agraphia 78
6 Apraxia 84
Limb-kinetic Apraxia 85
Ideomotor Apraxia 86
Ideational Apraxia 90
7 Agnosia 93
Visual Agnosia 94
Auditory Agnosia 100
Tactile Agnosia 101
8 Right Hemisphere Syndromes 106
Neglect 107
Constructional Apraxia 110
Topographical Disorientation 111
Dressing Apraxia 112
Aprosody 112
Amusia 114
Emotional Disorders 117
9 Temporal Lobe Syndromes 126
The Limbic System 126
Temporolimbic Epilepsy 130
Schizophreniform Psychosis 133
Temporolimbic Epilepsy Personality 136
10 Frontal Lobe Syndromes 145
Orbitofrontal Syndrome 149
Dorsolateral Syndrome 151
Medial Frontal Syndrome 153
Functions of the Frontal Lobes 154
11 Traumatic Brain Injury 160
Focal Lesions 162
Diffuse Lesions 163
12 Dementia 172
Cortical Dementias 175
Subcortical Dementias 180
White Matter Dementias 184
Mixed Dementias 190
Epilogue 202
Glossary of Neurobehavioral Terms 205
Index 215
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