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Doody's Review ServiceReviewer: Charles C Wang, MD, MS (University of Illinois at Chicago College of Medicine)
Description: This book reviews the new advances in the broad aspects of basic research and related clinical applications in the area of Alzheimer's disease. The first edition was published in 1995.
Purpose: The authors aim to provide an accessible overview of each of the predominant aspects of Alzheimer's disease. They wish to provide not only a readable introduction for those new to this subject, but also allow researchers to seek out and appeciate the overlap of their areas of expertise with other areas related to the disease. These are worthy objectives, which the author meets.
Audience: The audience will be reserchers in neurosicence with an interest in Alzheimer's disease and clincians including neurologists, geriatricians, and primary care physicains. The author is a credible authority in the subject matter of the book.
Features: The book covers broad topics in the basic neurobiology of Alzheimer's disease including neuropathology, molecular biology, genetics, imaging, diagnosis, and pharmacological approaches. The best aspects of the book are the comprehensive reviews of the advances in neuropathology, genetics, and molecular biology. These areas are well organized and illustrated.
Assessment: Alzheimer's disease is the most common dementia in the elderly. The vast expansion of knowledge in molecular biology and genetics makes the pathogenesis of the disease more understandable. The authors gather together the advances in knowledge on Alzheimer's disease in this well organized book. The audience will find the book a useful and handy reference. This new edition is justified because of the accumulation of research developements since the previous edition was published.