Neurobiology of Mental Illness / Edition 3

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Overview

The Third Edition of Neurobiology of Mental Illness provides a comprehensive and timely progress report on the neurobiologic foundations of psychiatry. The book begins with concise overviews of basic neuroscience and the methods used to study neuroscientific endpoints in human patients and then proceeds with discussions of all major psychiatric syndromes with respect to knowledge of the etiology, pathophysiology, and treatment. Emphasis is given to synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment.

The book contains predominantly black-and-white illustrations, with some color illustrations.

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Editorial Reviews

Michael J. Schrift
This is an outstanding and comprehensive textbook covering the current state of progress in the neurobiological mechanisms involved in neuropsychiatric disorders. Edited and authored by internationally recognized researchers, this is an exceptionally valuable contribution to this field. The purpose, according to the editors, is to track the evolving progress in the neurobiological basis of psychiatric illness and further the maturation of psychiatry as a modern medical specialty. The have certainly succeeded in their goal. The intended audience is psychiatrists and other mental health workers. It should be mandatory reading for residents in psychiatrist training programs. Part I is an overview of the basic neuroscientific underpinnings of psychiatry. Part 2 is a review of the ""tools that are currently available to study mental illness in humans."" The remaining sections cover such topics as dementia and childhood neuropsychiatric disorders. The sections begin with a critical overview of the diagnostic categories and the subsequent chapters are reviews of animal models, with current theories regarding the biological basis of specific psychopathologies followed by the neurobiological basis for treatment. Each chapter ends with up-to-date and useful references. The book ends with a useful index. This is an extremely valuable textbook on the biological basis of psychiatry. Clinicians and researchers as well as trainees will, without a doubt, benefit from reading and referring to it.
New England Journal of Medicine
This is not a how-to book for diagnosis and treatment, nor should it be regarded as offering an overview of schools of thought in modern psychiatry. It is, rather, a reference book on the neurobiologic underpinnings of our concepts of psychiatric illness. It should find a place on the shelf of practitioners in mental health-related fields, since it will help them interpret the reports they will see in the future on genetic and neuroanatomical abnormalities in their patients.
Doody's Review Service
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: This is the fourth edition of this absolutely first-rate and comprehensive book covering the progress made in understanding the neurobiological mechanisms involved in psychiatric disorders. Written and edited by the major researchers in psychiatry, this outstanding book remains a significant and important contribution to the field.
Purpose: The purpose is to update "the growing knowledge of all psychiatric syndromes - their etiology, pathophysiology and treatment." The editors state that, "No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text."
Audience: The intended audience is, according to the editors, "psychiatry residents, psychiatric researchers, and doctoral and post-doctoral fellows in the neurosciences."
Features: This edition is completely revised and divided into nine sections, now with 89 chapters. Part 1 is an overview of basic neuroscience with very informative chapters on brain development, electrophysiology, signal transduction, plasticity, molecular biology, and epigenetics. Part 2 covers new methods and technologies with chapters on such topics as transgenic models, stem cells, optogenetics, drug delivery, brain imaging, and image-guided brain stimulation. Parts 3 through 8, as in the previous edition, review the neurobiological aspects of psychoses, mood disorders, anxiety disorders, substance abuse disorders, dementia, and childhood onset disorders. Part 9 contains very interesting chapters on the DSM-5 and a critique of psychiatric diagnosis, the NIMH Research Domain, personality, aggression, social attachment, sleep, the neurobiology of resilience, and eating disorders. Each chapter ends with relevant and timely citations.
Assessment: This book continues to be an outstanding testament to the effort made towards a fundamental understanding of psychiatric disorders. The fourth edition is an excellent and complete update on the biological basis of psychiatric disorders. Every psychiatrist should read and refer to this book. It covers the basis of modern psychiatry.
From the Publisher

"The editors deserve tremendous credit for compiling a most useful reference text, and I am not aware of a similar textbook that is anywhere as comprehensive, up-to-date, or focused on the basic science of our field." --American Journal of Psychiatry


4 Stars! from Doody
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Product Details

  • ISBN-13: 9780195325331
  • Publisher: Oxford University Press
  • Publication date: 12/4/2008
  • Edition description: Older Edition
  • Edition number: 3
  • Pages: 1504
  • Product dimensions: 8.90 (w) x 11.10 (h) x 2.40 (d)

Meet the Author

Dennis S. Charney, M.D., is Professor of Psychiatry and Director of the Yale-NIMH Mental Health Research Center; Eric J. Nestler, M.D., Ph.D., is Elizabeth Mears and House Jameson Professor of Psychiatry and Neurobiology; Benjamin S. Bunney, M.D., is Charles B.G. Murphy Professor and Chair, Department of Psychiatry, and Professor of Pharmacology and of Neurobiology; all at the Yale University School of Medicine, New Haven, CT, USA

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Table of Contents

Pt. I Introduction to basic neuroscience Eric J. Nestler Nestler, Eric J.

Pt. II Methods of clinical neurobiological research Carol A. Tamminga Tamminga, Carol A.

Pt. III Psychoses Jeffrey A. Lieberman Lieberman, Jeffrey A.

Pt. IV Mood disorders Charles B. Nemeroff Nemeroff, Charles B.

Pt. V Anxiety disorders Antonia S. New New, Antonia S.

Pt. VI Substance abuse disorders Steven E. Hyman Hyman, Steven E.

Pt. VII Dementia Mary Sano Sano, Mary

Pt. VIII Psychiatric disorders of childhood onset Daniel S. Pine Pine, Daniel S.

Pt. IX Special topic areas Antonia S. New New, Antonia S.

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