Neurogenetic Syndromes: Behavioral Issues and Their Treatment / Edition 1

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Overview

An essential pediatrics textbook and professional reference, this cutting-edge volume sheds new light on neurogenetic syndromes using a promising clinical perspective: examining behavioral and psychological phenotypes, with a strong focus on the influence of genetics. Linking science with practice like no other current text on this topic, this comprehensive book combines the latest research of two dozen leading experts and shows how these advances in knowledge apply to treatment and therapy.

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Editorial Reviews

Neurodevelopmental Pediatrician, Janet Weis Children's Hospital, Geisinger Health System - Scott M. Myers
"Highly recommended . . . unique in its coverage of the theory and science of behavioral, cognitive, and social phenotypes as well as practical clinical information to guide diagnosis and treatment."
Professor and Director, The Lab for Cognitive Neuroscience, The Salk Institute for Biological Studies, La Jolla, CA - Ursula Bellugi
"A very important book which fills an immense void in the literature and is a must-read for those in the field and beyond . . . Strongly recommended."
Associate Professor of Pediatrics and Director, Center for Development and Learning, Kennedy Krieger Institute, Johns Ho - Paul H. Lipkin
"An important tool for the clinician seeking to expand knowledge on the treatment of genetic syndromes, while broadening the understanding of the links and interactions between the human genome and behavior."
Chief Academic Officer, Children's National Medical Center, Washington, DC - Mark L. Batshaw
"Shines an important light on the developing knowledge of the interplay between genes and environment in affecting behavior and how this understanding can lead to new approaches to treatment."
ADVANCE for Speech-Language Pathologists & Audiologists
"Informative and enjoyable…Packed with relevant information."
Journal of Genetic Counseling
"Drs. Shapiro and Accardo have struck a fine balance in developing this book. Practitioners of genetics, psychiatry, pediatrics, or basic science will each find enough familiar ground to feel comfortable reading this book."
American Journal of Psychiatry
"An outstanding book for both clinicians and researchers."
Research and Practice for Persons with Severe Disabilities
Do not use review
From the Publisher

"Drs. Shapiro and Accardo have struck a fine balance in developing this book. Practitioners of genetics, psychiatry, pediatrics, or basic science will each find enough familiar ground to feel comfortable reading this book."
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Product Details

  • ISBN-13: 9781598570175
  • Publisher: Brookes, Paul H. Publishing Company
  • Publication date: 11/1/2009
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 328
  • Sales rank: 1,105,531
  • Product dimensions: 7.20 (w) x 10.10 (h) x 0.90 (d)

Meet the Author

Pasquale J. Accardo, M.D., is Professor of Pediatrics at Virginia Commonwealth University in Richmond. He received his medical degree from Downstate Medical Center, Brooklyn, New York; completed his pediatric residency at James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, and obtained his developmental pediatrics training at the John F. Kennedy Institute for Handicapped Children (now called the Kennedy Krieger Institute), an affiliate of Johns Hopkins University School of Medicine, Baltimore, Maryland. He is subcertified in neurodevelopmental disabilities in pediatrics by the American Board of Pediatrics. Dr. Accardo is the author and editor of several books including Attention Deficit Hyperactivity Disorder: The Clinical Spectrum (York Press, 2001); Austim: Clinical and Research Issues (York Press, 2000), and Developmental Disabilities in Infancy and Childhood, Second Edition, Volumes I and II (Paul H. Brookes Publishing Co., 1996).

Bruce K. Shapiro, M.D. Professor of Pediatrics, The Johns Hopkins University School of Medicine; The Arnold J. Capute, M.D., M.P.H. Chair in Neurodevelopmental Disabilities; Vice President, Training, Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205

Travis Thompson, Ph.D., L.P., Graduate Faculty Member, Special Education Program, Department of Educational Psychology, University of Minnesota, Minneapolis, and Consulting Psychologist, Minnesota Early Autism Project, 7242 Forestview Lane North, Maple Grove, Minnesota 55369

Dr. Thompson is affiliated with the Autism Certificate Program in the Special Education Program of the Department of Educational Psychology at the University of Minnesota, and he is Adjunct Professor in the Department of Applied Behavioral Science at the University of Kansas, Lawrence. He is a collaborator on a multisite project on challenging behavior in developmental disabilities including the Kennedy Krieger Institute in Maryland; the Eunice Kennedy Shriver Center, University of Massachusetts, Amherst; and the University of Kansas, Parsons. He is a licensed psychologist.

Dr. Thompson completed his doctoral training in psychology at the University of Minnesota and completed postdoctoral work at the University of Maryland. He spent a year at Cambridge University in the United Kingdom and a year as a visiting scientist at the National Institute on Drug Abuse in Rockville, Maryland. Dr. Thompson was Director of the John F. Kennedy Center for Research on Human Development at Vanderbilt University and Director of the Institute for Child Development at the University of Kansas Medical Center—a clinical, training, and research institute. Dr. Thompson has served on several National Institutes of Health research review committees, including chairing reviews of the applicants for Collaborative Programs of Excellence in Autism awards in 2000, 2003, and 2007. He has been a member of American Psychological Association (APA) task forces concerned with the practice of psychology and psychopharmacology. He is a past president of the Behavioral Pharmacology Society, the Division of Psychopharmacology and Substance Abuse, and the Division of Mental Retardation and Developmental Disabilities of the APA.

Dr. Thompson has received numerous awards, including the Distinguished Research Award, The Arc of the United States; the Academy on Mental Retardation Lifetime Research Award; the APA's Don Hake Award; the Edgar A. Doll Award, for contributions to facilitate the transfer of research into practice; and the Ernest R. Hilgard Award and the Impact of Science on Application Award of the Society for Advancement of Behavior Analysis. He has served as cochair of the Association for Behavior Analysis International's Annual Autism Conference (2010 and 2011). He has published more than 230 journal articles and chapters and 30 books dealing with

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Table of Contents


Editors and Contributors
Preface
Acknowledgments

I: Neurogenetic Syndromes

  1. Behavioral Phenotypes: Recent Advances
    James C. Harris
  2. Smith-Magenis Syndrome: A Neurobehavioral Syndrome with Genetic Underpinnings
    Andrea L. Gropman & Ann C.M. Smith
  3. Fragile X: Expansion of a Genetic Disorder
    Walter E. Kaufmann
  4. Behavioral Phenotypes in Down Syndrome: A Probabilistic Model
    George T. Capone
  5. Autism and Prader-Willi Syndrome: Searching for Shared Endophenotypes
    Travis Thompson
  6. Williams Syndrome: Psychological Characteristics
    Carolyn B. Mervis & Angela E. John
  7. Developmental Influences on Psychological Phenotypes
    Gene S. Fisch
  8. Is There a Behavioral Phenotype in Children with Fetal Alcohol Syndrome Disorders?
    Piyadasa W. Kodituwakku

II: Treatment of Neurogenetic Syndromes

  1. Functional Behavioral Assessment: Its Value in the Treatment of Maladaptive Behaviors in Individuals with Neurogenetic Syndromes
    Theodosia R. Paclawskyj
  2. Psychiatric Diagnosis in Individuals with Neurodevelopmental Disability
    Richard B. Ferrell
  3. Speech Language Therapy for Children with Social, Emotional, and Behavioral Disorders
    Janet E. Turner & Mary K. Boyle
  4. A Clinical Approach to the Pharmacological Management of Behavioral Disturbance in Intellectual Disability
    Sarah Risen, Pasquale J. Accardo, & Bruce K. Shapiro
  5. Integrating Behavioral and Pharmacological Interventions for Severe Problem Behavior Displayed by Children with Neurogenetic and Developmental Disorders
    Louis P. Hagopian & Mary E. Caruso-Anderson

III. Future Implications

  1. New Genetic Techniques: Implications for Neurobehavioral Syndromes
    Lisa T. Emrick
  2. Genetically Informative Phenotypes: Opportunities for Progress and Potential Pitfalls
    Peter Szatmari
  3. Social Phenotypes in Genetically Based Neurodevelopmental Disorders
    Carl Feinstein & Shivani Verma
  4. Behavioral Phenotypes: Nature versus Nurture Revisited
    Pasquale J. Accardo & Margie L. Jaworski

Index

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