Neurogenetic Syndromes: Behavioral Issues and Their Treatment / Edition 1

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An essential pediatrics textbook and professional reference, this cutting-edge volume sheds new light on neurogenetic syndromes using a promising clinical perspective: examining behavioral and psychological phenotypes, with a strong focus on the influence of genetics. Linking science with practice like no other current text on this topic, this comprehensive book combines the latest research of two dozen leading experts and shows how these advances in knowledge apply to treatment and therapy.
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Editorial Reviews

Neurodevelopmental Pediatrician, Janet Weis Children's Hospital, Geisinger Health System - Scott M. Myers
"Highly recommended . . . unique in its coverage of the theory and science of behavioral, cognitive, and social phenotypes as well as practical clinical information to guide diagnosis and treatment."
Professor and Director, The Lab for Cognitive Neuroscience, The Salk Institute for Biological Studies, La Jolla, CA - Ursula Bellugi
"A very important book which fills an immense void in the literature and is a must-read for those in the field and beyond . . . Strongly recommended."
Associate Professor of Pediatrics and Director, Center for Development and Learning, Kennedy Krieger Institute, Johns Ho - Paul H. Lipkin
"An important tool for the clinician seeking to expand knowledge on the treatment of genetic syndromes, while broadening the understanding of the links and interactions between the human genome and behavior."
Chief Academic Officer, Children's National Medical Center, Washington, DC - Mark L. Batshaw
"Shines an important light on the developing knowledge of the interplay between genes and environment in affecting behavior and how this understanding can lead to new approaches to treatment."
ADVANCE for Speech-Language Pathologists & Audiologists
"Informative and enjoyable…Packed with relevant information."
Journal of Genetic Counseling
"Drs. Shapiro and Accardo have struck a fine balance in developing this book. Practitioners of genetics, psychiatry, pediatrics, or basic science will each find enough familiar ground to feel comfortable reading this book."
American Journal of Psychiatry
"An outstanding book for both clinicians and researchers."
Research and Practice for Persons with Severe Disabilities
Do not use review
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Product Details

  • ISBN-13: 9781598570175
  • Publisher: Brookes, Paul H. Publishing Company
  • Publication date: 11/1/2009
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 328
  • Product dimensions: 7.20 (w) x 10.10 (h) x 0.90 (d)

Meet the Author

Bruce K. Shapiro, M.D. Professor of Pediatrics, The Johns Hopkins University School of Medicine; The Arnold J. Capute, M.D., M.P.H. Chair in Neurodevelopmental Disabilities; Vice President, Training, Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205

Bruce K. Shapiro, M.D. Professor of Pediatrics, The Johns Hopkins University School of Medicine; The Arnold J. Capute, M.D., M.P.H. Chair in Neurodevelopmental Disabilities; Vice President, Training, Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205

Pasquale J. Accardo, M.D., is Professor of Pediatrics at Virginia Commonwealth University in Richmond. He received his medical degree from Downstate Medical Center, Brooklyn, New York; completed his pediatric residency at James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, and obtained his developmental pediatrics training at the John F. Kennedy Institute for Handicapped Children (now called the Kennedy Krieger Institute), an affiliate of Johns Hopkins University School of Medicine, Baltimore, Maryland. He is subcertified in neurodevelopmental disabilities in pediatrics by the American Board of Pediatrics. Dr. Accardo is the author and editor of several books including Attention Deficit Hyperactivity Disorder: The Clinical Spectrum (York Press, 2001); Austim: Clinical and Research Issues (York Press, 2000), and Developmental Disabilities in Infancy and Childhood, Second Edition, Volumes I and II (Paul H. Brookes Publishing Co., 1996).

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Table of Contents

I Neurogenetic Syndromes

1 Behavioral Phenotypes: Recent Advances James C. Harris Harris, James C. 3

2 Smith-Magenis Syndrome: A Neurobehavioral Syndrome with Genetic Underpinnings Andrea L. Gropman Gropman, Andrea L. Ann C. M. Smith Smith, Ann C. M. 15

3 Fragile X: Expansion of a Genetic Disorder Walter E. Kaufman Kaufman, Walter E. 29

4 Behavioral Phenotypes in Down Syndrome: A Probabilistic Model George T. Capone Capone, George T. 53

5 Autism and Prader-Willi Syndrome: Searching for Shared Endophenotypes Travis Thompson Thompson, Travis 71

6 Williams Syndrome: Psychological Characteristics Carolyn B. Mervis Mervis, Carolyn B. Angela E. John John, Angela E. 81

7 Developmental Influences on Psychological Phenotypes Gene S. Fisch Fisch, Gene S. 99

8 Is There a Behavioral Phenotype in Children with Fetal Alcohol Spectrum Disorders? Piyadasa W. Kodituwakku Kodituwakku, Piyadasa W. 115

II Treatment of Neurogenetic Syndromes

9 Functional Behavioral Assessment: Its Value in the Treatment or Maladaptive Behaviors in Individuals with Neurogenetic Syndromes Theodosia R. Paclawshyj Paclawshyj, Theodosia R. 130

10 Psychiatric Diagnosis in Individuals with Neurodevelopmental Disability Richard B. Ferrell Ferrell, Richard B. 153

11 Speech-Language Therapy for Children with Social, Emotional, and Behavioral Disorders Janet E. Turner Turner, Janet E. Mary K. Boyle Boyle, Mary K. 163

12 A Clinical Approach to the Pharmacological Management of Behavioral Disturbance in Intellectual Disability Sarah Risen Risen, Sarah Pasquale J. Accardo Accardo, Pasquale J. Bruce K. Shapiro Shapiro, Bruce K. 185

13 Integrating Behavioral and PharmacologicalInterventions for Severe Problem Behavior Displayed by Children with Neurogenetic and Developmental Disorders Louis P. Hagopian Hagopian, Louis P. Mary E. Caruso-Anderson Caruso-Anderson, Mary E. 217

III Future Implications

14 New Genetic Techniques: Implications for Neurobehavioral Syndromes Lisa T. Emrick Emrick, Lisa T. 243

15 Genetically Informative Phenotypes: Opportunities for Progress and Potential Pitfalls Peter Szatmari Szatmari, Peter 263

16 Social Phenotypes in Genetically Based Neurodevelopmental Disorders Carl Feinstein Feinstein, Carl Shivani Verma Verma, Shivani 277

17 Behavioral Phenotypes: Nature versus Nurture Revisited Pasquale J. Accardo Accardo, Pasquale J. Margie L. Jaworski Jaworski, Margie L. 293

Index 301

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