Neuroleptic-induced Movement Disorders: A Comprehensive Survey

Neuroleptic-induced Movement Disorders: A Comprehensive Survey

by Ramzy Yassa
     
 

Although generally beneficial, neuroleptics often cause adverse effects, of which movement disorders are the most serious in terms of frequency and persistence. This book was prepared with the aim of improving understanding and clinical management of these treatment-caused conditions. The authors address the historical, clinical and neurobiological aspects of the

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Overview

Although generally beneficial, neuroleptics often cause adverse effects, of which movement disorders are the most serious in terms of frequency and persistence. This book was prepared with the aim of improving understanding and clinical management of these treatment-caused conditions. The authors address the historical, clinical and neurobiological aspects of the most serious of these conditions, tardive dyskinesia, as well as related movement disorders such as parkinsonism, dystonia and akathisia. The authors also devote sections of the text to the measurement of tardive dyskinesia, geographical and ethnic variables, and management with novel neuroleptic agents and biofeedback.

Product Details

ISBN-13:
9780521033527
Publisher:
Cambridge University Press
Publication date:
12/28/2006
Edition description:
New Edition
Pages:
516
Product dimensions:
5.98(w) x 8.98(h) x 1.14(d)

Table of Contents

Contributors
Preface
1Neuroleptic-induced movement disorders: historical perspective3
2Aging and tardive dyskinesia13
3Gender as a factor in the development of tardive dyskinesia26
4The Yale tardive dyskinesia study: a prospective incidence study among long-term outpatients41
5Vulnerability to tardive dyskinesia in schizophrenia: an exploration of individual patient factors56
6Tardive dyskinesia and affective disorder69
7Diabetes mellitus and tardive dyskinesia82
8Other factors in the development of tardive dyskinesia99
9Neuroleptic treatment and tardive dyskinesia104
10Anticholinergic drugs as factors in the development of tardive dyskinesia117
11Neurochemistry of the basal ganglia129
12A reanalysis of the dopamine theory of tardive dyskinesia: the hypothesis of dopamine D[subscript 1]/D[subscript 2] imbalance141
13Tardive dyskinesia and phenylalanine metabolism: risk-factor studies161
14Neuroendocrinological studies of tardive dyskinesia175
15Cognitive deficits and tardive dyskinesia196
16Studies of tardive dyskinesia using computed tomography and magnetic-resonance imaging207
17Rodent and other animal models of tardive dyskinesia during long-term neuroleptic-drug administration: controversies and implications for the clinical syndrome225
18Instrument measurements of tardive dyskinesia241
19Cultural aspects of tardive dyskinesia in Asia259
20Tardive dyskinesia in North America and the Middle East267
21Tardive dyskinesia in Europe274
22Role of ethnicity in the development of tardive dyskinesia298
23Tardive dyskinesia in children and adolescents311
24Drug-induced parkinsonism341
25Clinical aspects of neuroleptic-induced dystonia381
26Tardive dystonia395
27Tardive akathisia409
28Development of novel antipsychotic drugs with reduced extrapyramidal side effects427
29GABAergic treatments for tardive dyskinesia454
30Using biofeedback to train suppression of the oral-lingual movements of tardive dyskinesia470
Index484

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