Neuroleptic-induced Movement Disorders: A Comprehensive Survey

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Overview

The most widely prescribed group of psychotropic drugs, neuroleptics are indispensable in the management of a majority patients with schizophrenia, as well as other psychoses, yet they are associated with troublesome adverse effects, of which movement disorders are the most serious.This book deals with historical, clinical and neurobiological aspects of tardive dyskinesia and related movement disorders such as parkinsonism, dystonia and akathisia. Sections are also devoted to the measurement of tardive dyskinesia, to geographical and ethnic differences, and to management with novel neuroleptic agents and biofeedback.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: This is an excellent new book covering the varieties of movement disorders induced by exposure to antipsychotic medications. Written and edited by internationally recognized experts in the field, this book is a valuable contribution to psychiatry.
Purpose: The purpose of the book is to improve clinicians understanding and clinical management of neuroleptic-induced movement disorders. The editors believe that we need to "study these iatrogenic conditions in depth so as to understand them better and improve the management of our patients." This book is a step toward that purpose.
Audience: The intended audience is those interested in understanding the clinical uses of neuroleptic agents and the research into their adverse side effects.
Features: The book features 494 pages divided into seven parts and 30 chapters. Topics covered include an historical perspective, clinical aspects of tardive dyskinesia, mechanisms underlying tardive dyskinesia, measurement of tardive dyskinesia, cross cultural aspects of tardive dyskinesia, drug induced parkinsonism and dystonia, and treatment of tardive dyskinesia. There is an up-to-date reference section and useful index at the back of the book.
Assessment: This is a valuable new book on drug-induced movement disorders. Any clinician who is involved in the treatment of patients with chronic psychoses should read and refer to this book.
Michael J. Schrift
This is an excellent new book covering the varieties of movement disorders induced by exposure to antipsychotic medications. Written and edited by internationally recognized experts in the field, this book is a valuable contribution to psychiatry. The purpose of the book is to improve clinicians understanding and clinical management of neuroleptic-induced movement disorders. The editors believe that we need to ""study these iatrogenic conditions in depth so as to understand them better and improve the management of our patients."" This book is a step toward that purpose. The intended audience is those interested in understanding the clinical uses of neuroleptic agents and the research into their adverse side effects. The book features 494 pages divided into seven parts and 30 chapters. Topics covered include an historical perspective, clinical aspects of tardive dyskinesia, mechanisms underlying tardive dyskinesia, measurement of tardive dyskinesia, cross cultural aspects of tardive dyskinesia, drug induced parkinsonism and dystonia, and treatment of tardive dyskinesia. There is an up-to-date reference section and useful index at the back of the book. This is a valuable new book on drug-induced movement disorders. Any clinician who is involved in the treatment of patients with chronic psychoses should read and refer to this book.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780521433648
  • Publisher: Cambridge University Press
  • Publication date: 10/28/1996
  • Edition description: New Edition
  • Pages: 481
  • Product dimensions: 5.98 (w) x 8.98 (h) x 1.22 (d)

Table of Contents

Contributors
Preface
1 Neuroleptic-induced movement disorders: historical perspective 3
2 Aging and tardive dyskinesia 13
3 Gender as a factor in the development of tardive dyskinesia 26
4 The Yale tardive dyskinesia study: a prospective incidence study among long-term outpatients 41
5 Vulnerability to tardive dyskinesia in schizophrenia: an exploration of individual patient factors 56
6 Tardive dyskinesia and affective disorder 69
7 Diabetes mellitus and tardive dyskinesia 82
8 Other factors in the development of tardive dyskinesia 99
9 Neuroleptic treatment and tardive dyskinesia 104
10 Anticholinergic drugs as factors in the development of tardive dyskinesia 117
11 Neurochemistry of the basal ganglia 129
12 A reanalysis of the dopamine theory of tardive dyskinesia: the hypothesis of dopamine D[subscript 1]/D[subscript 2] imbalance 141
13 Tardive dyskinesia and phenylalanine metabolism: risk-factor studies 161
14 Neuroendocrinological studies of tardive dyskinesia 175
15 Cognitive deficits and tardive dyskinesia 196
16 Studies of tardive dyskinesia using computed tomography and magnetic-resonance imaging 207
17 Rodent and other animal models of tardive dyskinesia during long-term neuroleptic-drug administration: controversies and implications for the clinical syndrome 225
18 Instrument measurements of tardive dyskinesia 241
19 Cultural aspects of tardive dyskinesia in Asia 259
20 Tardive dyskinesia in North America and the Middle East 267
21 Tardive dyskinesia in Europe 274
22 Role of ethnicity in the development of tardive dyskinesia 298
23 Tardive dyskinesia in children and adolescents 311
24 Drug-induced parkinsonism 341
25 Clinical aspects of neuroleptic-induced dystonia 381
26 Tardive dystonia 395
27 Tardive akathisia 409
28 Development of novel antipsychotic drugs with reduced extrapyramidal side effects 427
29 GABAergic treatments for tardive dyskinesia 454
30 Using biofeedback to train suppression of the oral-lingual movements of tardive dyskinesia 470
Index 484
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