Overview

Although there appears to be a general understanding that the human brain functions similarly in women and in men, an increasing body of knowledge indicates that neuronal connectivity, recruitment, and disease patterns exhibit gender differences. There are clear gender differences in genetic expression, physiologic function, metabolism, hormonal makeup, and psychosocial profile, which often modify the clinical expression of neurologic and other diseases. In addition, ethnic, cultural, and economic factors are ...
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Neurologic Disease in Women

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Overview

Although there appears to be a general understanding that the human brain functions similarly in women and in men, an increasing body of knowledge indicates that neuronal connectivity, recruitment, and disease patterns exhibit gender differences. There are clear gender differences in genetic expression, physiologic function, metabolism, hormonal makeup, and psychosocial profile, which often modify the clinical expression of neurologic and other diseases. In addition, ethnic, cultural, and economic factors are frequently overlooked in dealing with health problems of women, even though they undoubtedly have a strong influence on the clinical course of the illness.

The second edition of Neurologic Disease in Women, the only text to specifically cover this important topic, will help physicians and other medical personnel seeking information relevant to clinical care. Sections address general anatomic, hormonal, epidemiologic, and drug aspects of women's health; neurologic conditions that arise during childhood, pregnancy, adulthood, and old age in females; and particular neurologic conditions that present differently or predominantly in females.

There have been important advances in several areas prompting new chapters, new approaches and additional information provided in chapters on hormonal effects in women and the use of HRT; the adverse effects of antiepileptic drugs on hormonal homeostasis, weight and bone health; and cardiovascular diseases in women. New chapters include ones on reproductive and metabolic disorders with AED use, and on movement disorders.;"General Issues in Women; Sex Differences in Regional Brain Structure and Function; Gender Differences in Diseases of the Nervous System; Women's Lives and Their Experiences with Health Care; Drug Treatments and Trials in Women; Reproductive and Metabolic Disorders with AED Use; Efffect of Ovarian Hormones on the Nervous System; Genetic Neurologic Disorders in Females; Women, Law, and Neurologic Disease; Life Stages and Neurologic Disease in Women; Neurologic Disease in Girls; Menstruation and Pregnancy: Interactions with Neurologic Disease; Obstetric and Gynecologic Issues in Women with Neurologic Disease; The Menopausal Transition: Changing Physiology, Symptoms, and Hormone Therapy; Frailty in Elderly Women; Neurologic Disorders in Women; Migraine; Seizures and Epilepsy in Women; Eclampsia; Cerebrovascular Disease in Women; Multiple Schlerosis; Optic Neuritis; Peripheral Nerve Disease in Women; Muscle Disease in Women; Neurologic Presentations of Autoimmune Disorders in Women; Gender Differences in Movement Disorders; Chorea Gravidarum; Giant Cell Arteritis; Neurologic Basis of Common Pelvic Flood Disorders; Infections of the Nervous System in Women; Neuro-oncological Diseases in Women; Pseudomotor Cerebri; Alzheimer Disease in Women; Psychiatric Disorders in Women; Nonepileptic, Psychogenic, and Hysterical Seizures.";"...This book reminds us that women with neurologic disease deserve special attention...Neurologic Disease in Women presents the physiological, genetic, and anatomical aspects of neurology and gynecology in a clear and concise format that can be readily grasped by general health care providers."--The New England Journal of Medicine

"There are issues specific to females that influence both disease, investigation, and treatment (pregnancy, breast feeding, menopause, to name the most obvious) and that not all neurological diseases attack the sexes equally... [This is] a beautifully presented book; clearly headed and with wide use of well constructed tables. It encourages one to read on... not only a good addition to any neurological library but a useful purchase for anyone interested in female medical issues." -- Journal of Neurology, Neurosurgery, and Psychiatry

"Extremely accessible...Useful to general neurologists, internists, and primary care physicians who care for women with neurological disorders as well as students and residents...This is the sort of book that will serve as a useful reference when specific questions arise, and is also sufficiently accessible that individual chapters can be read from beginning to end." -- Doody's Reviews"

The book contains black-and-white illustrations.

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Editorial Reviews

Daniel B. Hier
This multiauthored text comprehensively addresses issues of neurologic disease in women. The purpose is to provide practicing physicians with a framework for addressing issues of epidemiology, expression, diagnosis, and treatment of neurologic disease in woman. This book is directed at practicing internists, neurologist, and obstetricians/gynecologists. Six preliminary chapters address general issues of how gender influences the brain and neurologic illnesses. Six additional chapters address neurologic illness across the woman's life cycle. The final twenty chapters address a variety of specific neurologic disorders including multiple sclerosis, seizure, and migraine. This is a well-edited, well-written, and comprehensive contribution to the field of neurologic disease in women. Many of the chapters are truly excellent. As a whole, this book stands out as a scholarly and valuable contribution to an emerging field.
From The Critics
Reviewer:Michael Benatar, MD, PhD(Emory University School of Medicine)
Description:This book, first published in 1998, is divided into three main sections. The first describes anatomic, physiologic, hormonal, and pharmacologic aspects of women's health. The second focuses on neurological disorders that occur during specific times of life (childhood, pregnancy, etc.), and the third includes a series of chapters devoted to neurological conditions that occur predominantly or present differently in women.
Purpose:The goal of this edited work is to assist physicians in locating information relevant to the diagnosis and treatment of neurological disorders in women. The importance of this goal is underscored by the known gender differences in the presentation and management of many neurological diseases. The content and organization of this book amply meet the stated objective.
Audience:This book is extremely accessible and will be useful to general neurologists, internists, and primary care physicians who care for women with neurological disorders as well as students and residents. The chapters are authored by recognized experts in the field.
Features:Neurologists are aware that several neurological disorders occur more frequently in women or during pregnancy and that this may dictate a different approach to the diagnosis and management of these conditions. This book provides a synthesis of issues that cross the boundaries of neurology, obstetrics, gynecology, and neonatology as well as disorders that span subspecialties within neurology. This multidisciplinary approach is one of the strengths of this book. Another strength lies in the nature of the information presented that may otherwise be quite difficult to locate. The chapter on genetic disorders in women that covers issues related to the manifestations and diagnosis of X-linked disorders in women is particularly helpful in this regard. One criticism is that the chapter on therapeutics during pregnancy might be expanded to also cover the use of high dose intravenous methylprednisolone as well as other immunosuppressive agents, issues only partly covered in the chapter on autoimmune disorders in women.
Assessment:Overall, this is a book that I am pleased to have on my shelf. It is the sort of book that will serve as a useful reference when specific questions arise, and is also sufficiently accessible that individual chapters can be read from beginning to end. There is another book that covers related material (Neurologic Diseases in Women, edited by Cudkowicz and Irizarry (Butterworth-Heinemann, 1997)), but I am insufficiently familiar with it to offer an authoritative comparison.
Booknews
Addresses the gender differences in genetic expression, physiologic function, metabolism, hormonal makeup, and psychosocial profile which often affect the clinical expression of neurologic and other diseases. Thirty-two chapters discuss general anatomic, hormonal, epidemiologic, and drug aspects of women's health; neurologic conditions that arise during childhood, pregnancy, adulthood, and old age; and particular neurologic diseases that present differently or predominantly in females. Annotation c. Book News, Inc., Portland, OR (booknews.com)

3 Stars from Doody
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Product Details

  • ISBN-13: 9781934559338
  • Publisher: Demos Medical Publishing, LLC
  • Publication date: 9/1/2005
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 2
  • File size: 7 MB

Meet the Author

Peter W. Kaplan, MD - Peter W. Kaplan, MD is Professor of Neurology at the Johns Hopkins Bayview Medical Center, Baltimore, MD.
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Table of Contents

1 Gender differences in diseases of the nervous system 3
2 Sex differences in regional brain structure and function 15
3 Women's lives and their experiences with health care 27
4 Drug treatment and trials in women 41
5 Reproductive and metabolic disorders with AED use 63
6 Effect of ovarian hormones on the nervous system 75
7 Genetic neurologic disorders in females 91
8 Women, law, and neurologic disease 115
9 Neurologic disease in girls 127
10 Menstruation and pregnancy : interactions with neurologic disease 147
11 Obstetric issues in women with neurologic diseases 151
12 The menopausal transition : changing physiology, symptoms, and hormone therapy 169
13 Frailty in elderly women 185
14 Migraine 201
15 Seizures and epilepsy in women 219
16 Eclampsia 235
17 Cerebrovascular disease in women 247
18 Multiple sclerosis 265
19 Optic neuritis 283
20 Peripheral nerve disease in women 297
21 Muscle disease in women 315
22 Neurologic presentations of autoimmune disorders in women 335
23 Gender differences in movement disorders 349
24 Chorea gravidarum 355
25 Giant cell arteritis 359
26 The neurologic basis of common pelvic floor disorders 367
27 Infections of the nervous system in women 379
28 Neuro-oncological diseases in women 387
29 Pseudomotor cerebri 393
30 Alzheimer disease in women 411
31 Psychiatric disorders in women 419
32 Nonepileptic, psychogenic, and hysterical seizures 445
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