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Neurologic Disease in Women
     

Neurologic Disease in Women

by Peter W. Kaplan
 

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Although there appears to be a general understanding that the human brain functions similarly in women and in men, an increasing body of knowledge indicates that neuronal connectivity, recruitment, and disease patterns exhibit gender differences. There are clear gender differences in genetic expression, physiologic function, metabolism, hormonal makeup, and

Overview

Although there appears to be a general understanding that the human brain functions similarly in women and in men, an increasing body of knowledge indicates that neuronal connectivity, recruitment, and disease patterns exhibit gender differences. There are clear gender differences in genetic expression, physiologic function, metabolism, hormonal makeup, and psychosocial profile, which often modify the clinical expression of neurologic and other diseases. In addition, ethnic, cultural, and economic factors are frequently overlooked in dealing with health problems of women, even though they undoubtedly have a strong influence on the clinical course of the illness.

The second edition of Neurologic Disease in Women, the only text to specifically cover this important topic, will help physicians and other medical personnel seeking information relevant to clinical care. Sections address general anatomic, hormonal, epidemiologic, and drug aspects of women's health; neurologic conditions that arise during childhood, pregnancy, adulthood, and old age in females; and particular neurologic conditions that present differently or predominantly in females.

There have been important advances in several areas prompting new chapters, new approaches and additional information provided in chapters on hormonal effects in women and the use of HRT; the adverse effects of antiepileptic drugs on hormonal homeostasis, weight and bone health; and cardiovascular diseases in women. New chapters include ones on reproductive and metabolic disorders with AED use, and on movement disorders.

Editorial Reviews

3 Stars from Doody
Daniel B. Hier
This multiauthored text comprehensively addresses issues of neurologic disease in women. The purpose is to provide practicing physicians with a framework for addressing issues of epidemiology, expression, diagnosis, and treatment of neurologic disease in woman. This book is directed at practicing internists, neurologist, and obstetricians/gynecologists. Six preliminary chapters address general issues of how gender influences the brain and neurologic illnesses. Six additional chapters address neurologic illness across the woman's life cycle. The final twenty chapters address a variety of specific neurologic disorders including multiple sclerosis, seizure, and migraine. This is a well-edited, well-written, and comprehensive contribution to the field of neurologic disease in women. Many of the chapters are truly excellent. As a whole, this book stands out as a scholarly and valuable contribution to an emerging field.
Booknews
Addresses the gender differences in genetic expression, physiologic function, metabolism, hormonal makeup, and psychosocial profile which often affect the clinical expression of neurologic and other diseases. Thirty-two chapters discuss general anatomic, hormonal, epidemiologic, and drug aspects of women's health; neurologic conditions that arise during childhood, pregnancy, adulthood, and old age; and particular neurologic diseases that present differently or predominantly in females. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Doody's Review Service
Reviewer: Michael Benatar, MD, PhD (Emory University School of Medicine)
Description: This book, first published in 1998, is divided into three main sections. The first describes anatomic, physiologic, hormonal, and pharmacologic aspects of women's health. The second focuses on neurological disorders that occur during specific times of life (childhood, pregnancy, etc.), and the third includes a series of chapters devoted to neurological conditions that occur predominantly or present differently in women.
Purpose: The goal of this edited work is to assist physicians in locating information relevant to the diagnosis and treatment of neurological disorders in women. The importance of this goal is underscored by the known gender differences in the presentation and management of many neurological diseases. The content and organization of this book amply meet the stated objective.
Audience: This book is extremely accessible and will be useful to general neurologists, internists, and primary care physicians who care for women with neurological disorders as well as students and residents. The chapters are authored by recognized experts in the field.
Features: Neurologists are aware that several neurological disorders occur more frequently in women or during pregnancy and that this may dictate a different approach to the diagnosis and management of these conditions. This book provides a synthesis of issues that cross the boundaries of neurology, obstetrics, gynecology, and neonatology as well as disorders that span subspecialties within neurology. This multidisciplinary approach is one of the strengths of this book. Another strength lies in the nature of the information presented that may otherwise be quite difficult to locate. The chapter on genetic disorders in women that covers issues related to the manifestations and diagnosis of X-linked disorders in women is particularly helpful in this regard. One criticism is that the chapter on therapeutics during pregnancy might be expanded to also cover the use of high dose intravenous methylprednisolone as well as other immunosuppressive agents, issues only partly covered in the chapter on autoimmune disorders in women.
Assessment: Overall, this is a book that I am pleased to have on my shelf. It is the sort of book that will serve as a useful reference when specific questions arise, and is also sufficiently accessible that individual chapters can be read from beginning to end. There is another book that covers related material (Neurologic Diseases in Women, edited by Cudkowicz and Irizarry (Butterworth-Heinemann, 1997)), but I am insufficiently familiar with it to offer an authoritative comparison.

Product Details

ISBN-13:
9781934559338
Publisher:
Springer Publishing Company
Publication date:
09/01/2005
Sold by:
Barnes & Noble
Format:
NOOK Book
Pages:
1000
File size:
6 MB

Meet the Author

Peter W. Kaplan, MD - Peter W. Kaplan, MD is Professor of Neurology at the Johns Hopkins Bayview Medical Center, Baltimore, MD.

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