Neurology and Clinical Neuroscience: Text with CD-ROM

Hardcover (Print)
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This brand-new text provides you with an easy-to-use, comprehensive reference that features a clinical perspective balanced with relevant basic science. Inside, you'll find discussions of the latest research and how it has led to a greater understanding of the cause of disease, as well as burgeoning tests and the latest therapeutic agents available. From Alzheimer's disease to vestibular system disorders, you'll find the practical guidance you need to diagnose effectively and provide an appropriate therapeutic approach for each individual case. Plus, a templated, four-color design offers you easy access to pertinent information

• Integrates basic science with clinical neurology to help you better understand neurologic diseases and provide the most accurate diagnosis and best treatment plan for each patient.
• Discusses the latest research results and offers new information on treatment options.
• Features the expertise of international authorities, providing a worldwide perspective.
• Includes a CD-ROM image bank of the text's illustrations downloadable into PowerPoint® presentations.
• Uses a templated, four-color format that makes information accessible and easy to understand—particularly the basic science concepts.

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Editorial Reviews

Doody's Review Service
Reviewer: George F Wittenberg, M.D., Ph.D.(University of Maryland School of Medicine)
Description: This multiauthored book is meant to be a review of neurology for both experienced practitioners and trainees. It attempts to distinguish itself from other general neurology textbooks by incorporating recent advances in imaging and molecular biology.
Purpose: The idea that other books do not incorporate the latest scientific advances is only partly true. One might also question whether trying to address the twin objectives of complete coverage of clinical neurology along with scientific advances in neurology is truly workable, as some subfields have advanced much more than others. The result is an even more heterogeneous book than most multiauthored texts.
Audience: The book is written for all neurologists, at any level, who wish to review neurology (perhaps for a board exam or recertification?), but would make more sense for more junior readers. Numerous authorities have written chapters, including the editors, but other authors are fellows and residents.
Features: As with many traditional neurology books, mental status is covered at the beginning and a short discussion of evaluation tools follows. There is a stated special emphasis in neuro-oncology, but otherwise the scope and organization are similar to neurology clinical textbooks from the past. In fact, most topics are not covered in great depth, even neuro-oncology, although headache receives the fullest coverage. Color figures are attractive and provided in a CD with the book. The images are organized by a Javascript application, viewed through any web browser, and can be used to create an HTML presentation. The figures can also be viewed as PDFs, but the images are also on the CD in jpg format. Although the images are generally of high quality, there are some exceptions. The computer generated pictures of a poorly managed and well managed older patient are almost comical, but do make their point. Some choices of pictures can be questioned. Why a crude map of Venezuela only to show two towns in the Lake Maracaibo region? The graphic on multiple sclerosis had hardly any data on countries on the equator, yet makes the assertion that the disease is almost absent there. Why is there no data on Japan or Israel, among other countries? One special feature is a "Key Points" box at the end of each chapter which presents the take-home message for the distractible reader. Autism and ADHD are combined in one chapter. Besides being pediatric behavioral disorders, they seem to have little in common, although they seem to fit a theoretical rubric of the author. Among other pediatric disorders, cerebral palsy is given short shrift, despite its prevalence, and treatment is ignored. Psychiatric disorders are covered, albeit briefly, but even this is more than in some neurology textbooks.
Assessment: This book is like a pathophysiology text, such as Gilman's Neurobiology of Disease (Elsevier, 2007), combined with Rowland's Merritt's Neurology, 11th edition (Lippincott Williams & Wilkins, 2005). As such it is partly successful at making clinicians aware of the scientific basis of the profession, but that scientific basis is also quite spotty, through no fault of the authors. On the other hand, the book is marred by pretty but unhelpful illustrations and a large degree of inconsistency in carrying out its stated mission.
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Product Details

  • ISBN-13: 9780323033541
  • Publisher: Elsevier Health Sciences
  • Publication date: 12/18/2006
  • Pages: 1664
  • Product dimensions: 8.80 (w) x 11.20 (h) x 2.40 (d)

Table of Contents


1. Clinical Assessment
2. Neuropsychometric Assessment
3. Coma and Brain Death
4. Persistent Vegetative State
5. Hypoxic Brain Damage and Cerebral Palsy
6. Hydrocephalus
7. Disorders of Consciousness
8. Disorders of Memory
9. Autism and Attention Deficit Hyperactivity Disorder
10. Disorders of Speech and Language
11. Disorders of Swallowing
12. Disorders of Taste and Smell


13. Physiology and Pathology
14. REM Disorders
15. Narcoplepsy


16. Tourette’s Syndrome and Obsessive-Compulsive Disorders
17. Schizophrenia
18. Mania
19. Conversion Syndromes


20. Examination of the Visual System
21. Anterior Ischemic Optic Neuropathies
22. Retinal Disease
23. Genetic Causes of Blindness


24. Examination of Hearing and Balance
25. Auditory System Disorders
26. Vestibular System Disorders


27. Physiology and Pathology
28. Bladder Function and Dysfunction
29. Sexual Function and Dysfunction
30. Degenerative Disease


31. Organization: Pyramidal System
32. Organization: Extrapyramidal System
33. Apraxia
34. Parkinson Disease
35. Multiple System Atrophy and PSP
36. Tremor
37. Myoclonus
38. Dystonia
39. Tics
40. Gait and Balance
41. Restless Leg Syndrome


42. Developmental Disorders
43. Primary Myelopathies (Degenerative, Infective, Metabolic)
44. Spinal Trauma
45. Spinal Disease (Degenerative, Infective, Neoplastic, Cord Compression)


46. Anatomy and Physiology of Cerebral and Cord Circulation
47. Epidemiology, Genetics, Risk Factors, and Primary Prevention
48. Acute Stroke: Syndrome Including Cardiogenic Sources, Treatment, and Secondary Prevention
49. Intracranial Hemorrhage (Aneurysmal, Idiopathic, Hypertensive)
50. Arteriovenous Malformations of Brain and Spinal Cord
51. Procoagulopathy Disorders (Hypercoagulable States)
52. Cerebral Venous Thrombosis53. Vascular Dementia

X. Epilepsy

54. Developmental Defects and Epilepsy
55. Cellular Pathophysiology of Epilepsy
56. Genetics
57. Clinical Spectrum
58. Assessment and Management Principles
59. Drug Treatment
60. Surgical Treatment
61. Management of Status Epilepticus


62. Current Concepts of Pain, Perception, and Management
63. Chronic Daily Headache
64. Migraine
65. Cluster Headache, SUNCT
66. Trigeminal Neuralgia and Other Facial Pains
67. Idiopathic Intracranial Hypertension


68. Alzheimer Disease
69. Amyotrophic Lateral Sclerosis
70. Huntington Disease
71. Spinocerebellar Ataxias72. Hereditary Spastic Paraplegias
73. Lewy Body Disease
74. Frontotemporal Dementias


75. Epidemiology and Genetics
76. Pathophysiology of MS: Demyelination and Axonal Injury
77. Clinical Spectrum: Definition, Natural Progression, ADEM
78. Imaging in MS: Clinical and Radiological Correlates
79. Management of MS
80. Leukodystrophies


81. Anatomy and Physiology of Muscle and Nerve
82. Inherited Neuropathies
83. Toxic and Metabolic Neuropathies
84. Infective Neuropathies
85. Vasculitides


86. Muscular Dystrophies
87. Congenital Myopathies
88. Channelopathies of Muscle (incl Myotonic Dystrophy)
89. Metabolic Myopathies (incl Mitochondrial Disorders)
90. Inflammatory Myopathies
91. Neuromuscular Junction Disorders


92. Encephalitis
93. Meningitis
94. Neurology of HIV
95. Parasitic and Fungal Infections
96. Prion Diseases
97. Neurosarcoidosis and Behçet Disease
98. Collagen Vascular Diseases


99. Tumors of the Brain
100. Tumors of the Spinal Cord
101. Pituitary Tumors
102. Paraneoplastic Disorders of the Nervous System


103. Head Trauma
104. Peripheral Nerve Injury
105. Neurorehabilitation


106. Encephalopathies
107. Wilson Disease
108. Vitamin Deficiencies
109. Urea Cycle Disorders
110. Environmental Toxins

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