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Neuromuscular Block / Edition 1

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1996 Trade paperback New. No dust jacket as issued. Trade paperback (US). Glued binding. 192 p. Audience: General/trade. *****PLEASE NOTE: This item is shipping from an ... authorized seller in Europe. In the event that a return is necessary, you will be able to return your item within the US. To learn more about our European sellers and policies see the BookQuest FAQ section***** Read more Show Less

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Overview

A clinically orientated monograph covering the mechanism of neuromuscular block, its reversal and the clinical importance of the various factors that affect it. The aim is to make basic science understandable to the practising anaesthetist.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: J. Lance Lichtor, MD (University of Chicago Pritzker School of Medicine)
Description: This monograph is a review of the neuromuscular junction and of how muscle relaxants work. It is extremely well written and easy to understand.
Purpose: The author's purpose in writing this book is to explain both what is and what is not known about the neuromuscular junction and drugs that have an effect there. These objectives are worthy, and the author does an excellent job in meeting them.
Audience: The book, in my opinion, is useful for the medical student to understand neurotransmission and the workings of the neuromuscular junction; for the anesthesia or critical care physician who gives drugs to effect neuromuscular block; for an individual beginning research on muscle relaxants; and for the practicing physician as an excellent review.
Features: The author is a credible authority, having written many articles and two books on this topic. The quality of the illustrations is very good and the book is appropriately illustrated. References are current. The book, overall, has a nice appearance.
Assessment: The book is unique in that it is written by a single author who writes very well. The chapters are well organized into discrete and appropriate topics. The author, in the preface, states that is not meant to be a definitive textbook on muscle relaxants. In fact, two muscle relaxants, one that is currently in use (cisatracurium) and one that may soon be used (ORG 9487) are not mentioned. Yet, a sufficient background is given on the entire subject, so that these omissions are hardly noticed. This book is highly recommended for libraries, bookstores, and individuals who use muscle relaxants.
J. Lance Lichtor
This monograph is a review of the neuromuscular junction and of how muscle relaxants work. It is extremely well written and easy to understand. The author's purpose in writing this book is to explain both what is and what is not known about the neuromuscular junction and drugs that have an effect there. These objectives are worthy, and the author does an excellent job in meeting them. The book, in my opinion, is useful for the medical student to understand neurotransmission and the workings of the neuromuscular junction; for the anesthesia or critical care physician who gives drugs to effect neuromuscular block; for an individual beginning research on muscle relaxants; and for the practicing physician as an excellent review. The author is a credible authority, having written many articles and two books on this topic. The quality of the illustrations is very good and the book is appropriately illustrated. References are current. The book, overall, has a nice appearance. The book is unique in that it is written by a single author who writes very well. The chapters are well organized into discrete and appropriate topics. The author, in the preface, states that is not meant to be a definitive textbook on muscle relaxants. In fact, two muscle relaxants, one that is currently in use (cisatracurium) and one that may soon be used (ORG 9487) are not mentioned. Yet, a sufficient background is given on the entire subject, so that these omissions are hardly noticed. This book is highly recommended for libraries, bookstores, and individuals who use muscle relaxants.
Booknews
Feldman (anaesthetics, U. of London) speculates on some of the paradoxes which appear in clinical practice when administering neuromuscular blocking agents, offering new information and explanations based on the author's own experience. Some of the subject matter covered in the theoretical work examines acetylcholine formation and metabolism, biophase binding, pharmacokinetics, second dose drug sensitivity, hypothermia and neuromuscular block, and a review of muscle relaxant drugs. Annotation c. Book News, Inc., Portland, OR (booknews.com)

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780750617642
  • Publisher: Elsevier Health Sciences
  • Publication date: 4/1/1996
  • Edition number: 1
  • Pages: 192

Table of Contents

Preface; Introduction; History; The Neuromuscular junction; Neuromuscular transmission; Acetylcholine: formation and metabolism; Neuromuscular block (non depolarizing); Isolated arm experiments; Explanations of clinical events based on biophase binding; Pharmacokinetics and pharmacokinetic models; Onset of action of non-depolarizing drugs; Presynaptic nicotinic receptors; Reversing the action of non-depolarizing drugs; Sensitivity to a second dose of drug; The priming principle; Depolarizing neuromuscular block; Hypothermia and neuromuscular block; Monitoring neuromuscular conduction; Ideal muscle relaxant; The muscle relaxant drugs; Index

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