The Neuron: Cell and Molecular Biology / Edition 3

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Overview

Levitan, Irwin B.(Brandeis Univ); Kaczmarek, Leonard K.(Yale Univ)

The book contains both black-and-white and two-color illustrations.

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Editorial Reviews

From the Publisher
Praise from the Previous Edition
"The format of each chapter is ideally suited for easy, enjoyable and almost effortless learning.... In summary, this is a superbly written and well-illustrated text covering all the major aspects of neuroscientific knowledge.... Regardless of the state of knowledge or the specific expertise of the reader, every neuroscientist should keep a copy handy." — Journal of Psychiatry and Neuroscience

"Overall I consider this to be an outstanding, easily readable, and quite up-to-date overview of fundamental neurobiology. This book is quite useful for the clinician who wishes to have a digestible presentation of basic neuroscience as a prelude to understanding neurological disease." —Canadian Journal of Neurological Sciences

"The format of each chapter is ideally suited for easy, enjoyable and almost effortless learning.... In summary, this is a superbly written and well-illustrated text covering all the major aspects of neuroscientific knowledge.... Regardless of the state of knowledge or the specific expertise of the reader, every neuroscientist should keep a copy handy." — Journal of Psychiatry and Neuroscience

"Overall I consider this to be an outstanding, easily readable, and quite up-to-date overview of fundamental neurobiology. This book is quite useful for the clinician who wishes to have a digestible presentation of basic neuroscience as a prelude to understanding neurological disease." —Canadian Journal of Neurological Sciences

Praise for Third Edition
"In spite of the overwhelming amount of information on all things neuronal, the authors have succeeded in providing in-depth coverage on many new discoveries in neuroscience and integrating the material into a readable text. ... The Neuron promises to be a very useful textbook ... and a helpful introductory guide for scientists just becoming interested in the nervous system."—The Quarterly Review of Biology

Alexander Kolchinsky
This is the second edition of a textbook of neurobiology. It consists of 18 chapters divided into an introduction and three parts: electrical properties of neurons; intercellular communications between neurons; and higher level functions of neurons, plasticity, and behavior. It presents general concepts and describes crucial experiments and general experimental approaches. The book provides the background of neuroscience at the level of molecular and physiological properties of individual neurons. Admitting that this approach to neuroscience is close to reductionism, the authors justly state that this is the best route to understanding the more complicated issues. The textbook will be used by undergraduate and early graduate students beginning to take courses in neuroscience. It may also be used by physicians and even mature researchers as an introductory course and reference book. The book has attractive black and red layout, structured table of contents, and index. It is richly illustrated by schemes, graphs, and occasional electron micrographs. Many of these have exceptional educational value as visual support to any relevant teaching. All references to individual chapters are provided at the end of the book and are divided into recommended reading and references. The reason for this division is not clear, because both categories include a peculiar mix of recent reviews, various textbooks, and original papers sometimes going back to the 19th century and published in foreign languages. This is a remarkable textbook, a source of choice for teachers and students at the undergraduate and early graduate level. It presents the complicated field with such clarity that it is as muchfun to read as it was to write, according to the authors' preface.
Doody's Review Service
Reviewer: Celso Agner, MD, MS, MSc (Michigan Neurology Partners)
Description: The development of current molecular biology and immunocytochemistry triggered the evolution of neurology and neurosurgery, as novel forms of therapy could be adapted based on the experimental findings. This book is a necessary and required update on the topic.
Purpose: The main purpose of this book is to address the developments in the study of molecular biology of cells and how extrinsic influences help in organizing activities in the central nervous system. These are worthy and important objectives in today's clinical practice and the authors fully meet their objectives.
Audience: The audience is primarily neuroscientists and neurologists who are interested in the applied physiology of the nervous system and are able to incorporate the information discussed in this book into the understanding of ailments of the nervous system. These readers will find this a useful reference. The authors are credible authorities in the field.
Features: Throughout its pages, this book approaches neuroscience in a practical fashion, i.e., how can the modern understanding of neurophysiology, anatomy, and immunochemistry help in figuring out the etiology of diseases of the nervous system. Among the best aspects of the book is the constant interaction and reference to current issues in neurology. The pictures are well done and self explanatory. The references are up-to-date and provide a full view of the topics by experts in the field.
Assessment: This is a necessary component of any neuroscience library. Both the text and the graphics provide enjoyable, informative, and up-to-date reading for neurologists and neuroscientists alike..

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780195145229
  • Publisher: Oxford University Press, USA
  • Publication date: 10/28/2001
  • Edition description: REV
  • Edition number: 3
  • Pages: 632
  • Product dimensions: 9.00 (w) x 6.50 (h) x 1.60 (d)

Meet the Author

Irwin B. Levitan, Ph.D., Founding Chair of the Department of Neuroscience at Jefferson Medical College, Thomas Jefferson University

Leonard K. Kaczmarek, Ph.D., Professor of Pharmacology and Cellular and Molecular Physiology, Yale University School of Medicine.

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Table of Contents

I Introduction 3
1 Signaling in the Brain 5
2 Form and Function in Cells of the Brain 25
II Electrical Properties of Neurons 45
3 Electrical Signaling in Neurons 47
4 Membrane Ion Channels and Ion Currents 67
5 Ion Channels Are Membrane Proteins 89
6 Ion Channels, Membrane Ion Currents, and the Action Potential 113
7 Diversity in the Structure and Function of Ion Channels 139
III Intercellular Communication 163
8 How Neurons Communicate: Gap Junctions and Neurosecretion 165
9 Synaptic Release of Neurotransmitters 195
10 Neurotransmitters and Neurohormones 223
11 Receptors and Transduction Mechanisms I: Receptors Coupled Directly to Ion Channels 253
12 Receptors and Transduction Mechanisms II: Indirectly Coupled Receptor/Ion Channel Systems 285
13 Neuromodulation: Mechanisms of Induced Changes in the Electrical Behavior of Nerve Cells 315
14 Sensory Receptors 341
IV Behavior and Plasticity 373
15 The Birth and Death of a Neuron 375
16 Neuronal Growth and Trophic Factors 395
17 Adhesion Molecules and Axon Pathfinding 435
18 Formation, Maintenance, and Plasticity of Chemical Synapses 467
19 Neural Networks and Behavior 507
20 Learning and Memory 537
Bibliography 571
Index 589
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