Neuropathology: A Reference Text of CNS Pathology


Solve your toughest neurodiagnostic challenges with Neuropathology, 3rd Edition - the most information-packed, extensively illustrated neuropathology reference available! An expert author team presents more than 3,000 high-quality images - nearly all in full color - to provide unmatched visual guidance on the microscopic and gross pathologic presentation of a full range of neurologic diseases.

• Diagnose with confidence
by consulting the most ...

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Solve your toughest neurodiagnostic challenges with Neuropathology, 3rd Edition - the most information-packed, extensively illustrated neuropathology reference available! An expert author team presents more than 3,000 high-quality images - nearly all in full color - to provide unmatched visual guidance on the microscopic and gross pathologic presentation of a full range of neurologic diseases.

• Diagnose with confidence
by consulting the most extensive published image collection in neuropathology, which includes an exceptional number of gross pathology images, a feature poorly represented in other texts.
Access the complete contents online and download all the images at

• Understand the most recent developments in neurologic diseases
and quickly identify important variants and outliers.
Meet the needs of an aging population with expanded coverage of Alzheimer's and Parkinson's disease, motor neuron disorders, and prion diseases, as well as conditions such as multiple sclerosis.
Apply the latest knowledge on molecular genetics and the growing role of genetic testing.
Make optimal use of today’s functional imaging techniques with new information on PET, fMRI, and SPECT.
Stay current with the newest diagnostic protocols and guidelines as endorsed by professional societies and national bodies, the most recent WHO classification of central nervous system diseases, and checklists for the handling and diagnosis of CNS tumors and tumor-like lesions.
Get outstanding visual guidance with new full-color images, and new and updated drawings that clarify complex entities and concepts.

The book contains predominantly color illustrations, with some black-and-white illustrations.

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Editorial Reviews

Robert Wollman
This is a comprehensive introductory and reference textbook of neuropathology organized according to the classic divisions of pathology of the nervous system. The authors' aim is to produce a reference in which information is presented in ""an integrated, rapidly accessible format."" Much of the information is incorporated in color illustrations with appropriate and succinct accompanying text, tables, and diagrams which are meant to facilitate clinicopathological correlations. This book is designed for use as an introductory text for pathologists, neurologists, and neurosurgeons in training and will remain useful as a reference text for those already in practice for many years to come. This is the most extensively illustrated neuropathology text ever published. Most of the illustrations are in color and of excellent quality. And, as the authors correctly state in the preface, ""a clear illustration is often worth more than a page of prose."" The illustrations include a prodigious amount of gross pathology, a feature poorly represented in all other neuropathology texts. The most current theories of pathogenesis are illustrated with sophisticated diagrams. References are limited and tend to include mostly recent reviews which are more useful than extensive bibliographies usually found in texts of this nature. This is undoubtedly the best neuropathology textbook now in publication. By virtue of the extensive illustrations, all of which enhance the essential but succinct text, and the addition of clearly outlined theories of pathogenesis which include current information, this text belongs in the library of every medical institution and every department responsible for training youngphysicians in diagnosis and treatment of diseases of the nervous system.
Doody's Review Service
Reviewer: Kathy L Newell, MD (University of Kansas Medical Center)
Description: This general neuropathology reference is filled with high-quality illustrations, colorful cartoon drawings, tables, and boxes containing bulleted disease-specific information. Color-coding is used to highlight important information on pathogenesis, clinical data, and differential diagnosis or practical tips relevant to diagnosis. The first edition of this text appeared in 1998.
Purpose: The goal of the authors was to create a richly illustrated neuropathology reference that would serve as more than an atlas. The need for this type of resource is great in such a visually based discipline, and the high quality of the book's illustrations with supporting text and bulleted items meet this goal.
Audience: The authors have written the book with diagnostic pathologists and neuropathologists in mind; however, the format of this book is appropriate for students and residents, including those in other disciplines, such as neurology and neurosurgery. The lead authors, Drs Ellison and Love, are experienced and well recognized neuropathologists as are Drs Chimelli, Harding, Lowe, and Vinters.
Features: The book offers a comprehensive overview of major neuropathology topics in 10 areas, including general neuropathological principles, developmental disorders, vascular diseases, trauma, infections, demyelinating disease, metabolic and nutritional disorders, toxic injury, neurodegenerative disorders, and neoplasms. An accompanying CD, tucked into a plastic pocket inside the front cover, holds images and diagrams from the text in PDF or JPG formats to facilitate teaching presentations. The majority of the images, both in the text and on the CD, are of high quality and resolution, and exceed the quality of several other current neuropathology references. The tables and colorful diagrams are well executed, useful adjuncts to the text. The chapters on neurodegenerative diseases contain tables with useful summaries of clinical and neuropathological data, updated genetic information, and photographs highlighting key immunohistochemical reactions. More obscure subjects and details of animal-based models of human disease are not included. The reference lists have grown considerably, with updates, since the first edition, but an extensive bibliography is not a feature, and the text does not carry literature citations.
Assessment: This reference is a rich resource of high quality color gross and microscopic photographs with supporting text, diagrams, tables, and boxes that contain concise, pertinent information about the majority of the diseases that affect the human nervous system. The images, both in the print version and on CD, surpass those found in the current Greenfield's Neuropathology text and CD. The addition of new entities along with new updates on existing disorders, more references, and expansion of topics from the first edition justify this new edition.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780723435150
  • Publisher: Elsevier Health Sciences
  • Publication date: 2/18/2013
  • Edition description: New Edition
  • Edition number: 3
  • Pages: 900
  • Sales rank: 321,182
  • Product dimensions: 9.80 (w) x 12.20 (h) x 1.60 (d)

Table of Contents

Preface to First Edition
Preface to Second Edition
1 Pathologic reactions in the CNS
Ch. 1 Pathologic reactions in the CNS
2 Pediatrics
Ch. 2 Fetal and neonatal hypoxic-ischemic lesions
Ch. 3 Malformations
Ch. 4 Hydrocephalus
Ch. 5 Disorders that primarily affect white matter
Ch. 6 Neurodegenerative disorders of gray matter in childhood
Ch. 7 Miscellaneous pediatric disorders
3 Vascular disorders
Ch. 8 Adult hypoxic and ischemic lesions
Ch. 9 Vascular disease and infarcts
Ch. 10 Hemorrhage
4 Trauma
Ch. 11 Head and spinal injuries
5 Infectious disease
Ch. 12 Acute viral infections
Ch. 13 Chronic and subacute viral infections of the CNS
Ch. 14 Rickettsial and mycoplasma infections
Ch. 15 Acute bacterial infections and bacterial abscesses
Ch. 16 Chronic bacterial infections and neurosarcoidosis
Ch. 17 Fungal infections
Ch. 18 Parasitic infections
6 Demyelinating diseases
Ch. 19 Multiple sclerosis
Ch. 20 Other demyelinating diseases: inflammaton and compressive
7 Nutritional and metabolic disorders
Ch. 21 Vitamin deficiencies
Ch. 22 Systemic metabolic disease
Ch. 23 Lysosomal and peroxisomal disorders
Ch. 24 Mitochondrial encephalopathies
8 Toxic injury
Ch. 25 Toxic injury of the CNS
9 Neurodegenerative diseases
Ch. 26 Classification and pathogenesis of neurodegenerative disorders
Ch. 27 Motor neuron disorders
Ch. 28 Parkinsonism and akinetic-rigid disorders
Ch. 29 Ataxic disorders
Ch. 30 Hyperkinetic movement disorders
Ch. 31 Dementias
Ch. 32 Prion diseases
Ch. 33 Thalamic and pallidal degenerations, neuroaxonal dystrophy and autonomic failure
10 Neoplasms
Ch. 34 Classification and general concepts of CNS neoplasms
Ch. 35 Astrocytic neoplasms
Ch. 36 Non-astrocytic gliomas
Ch. 37 Neuroepithelial neoplasms displaying neuronal features
Ch. 38 Embryonal neuroepithelial neoplasms of the CNS
Ch. 39 Neoplasms of the pineal gland
Ch. 40 Choroid plexus neoplasms
Ch. 41 Primary CNS lymphomas
Ch. 42 Peripheral nerve sheath neoplasms
Ch. 43 Meningiomas
Ch. 44 Neoplasms in the region of the pituitary fossa
Ch. 45 Miscellaneous CNS neoplasms and cysts
Ch. 46 Neoplasms that spread to the CNS
Ch. 47 Paraneoplastic disorders
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