Neuroscience: From the Molecular to the Cognitive

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Overview

This hundredth volume is a commemorative milestone in the prestigeous Progress in Brain Research series. Accordingly, authors were invited to write on any topic, given that their choice represented the topic most near and dear to their own efforts over a significant period of the recent past, and to which they would likely continue to be devoted in the future.

In that sense, this volume does not represent a scientific meeting, but rather an overview sample of problems and methodologies that epitomize brain research broadly at this special moment in the maturation of the field.

The chapters comprising this volume assort themselves readily into five or six established categories of topics: developmental brain research, molecular brain research, integrative brain research, neuroplasticity, and neuro-psychiatric conditions.

This volume reports through a sample of recognized leaders in the neuroscientific community at a significant instant in the history and evolution of the field.

This hundredth volume is a commemorative milestone in the prestigeous Progress in Brain Research series. Accordingly, authors were invited to write on any topic, given that their choice represented the topic most near and dear to their own efforts over a significant period of the recent past, and to which they would likely continue to be devoted in the future.

In that sense, this volume does not represent a scientific meeting, but rather an overview sample of problems and methodologies that epitomize brain research broadly at this special moment in the maturation of the field.

The chapters comprising this volume assort themselves readily into five or six established categories of topics: developmental brain research, molecular brain research, integrative brain research, neuroplasticity, and neuro-psychiatric conditions.

This volume reports through a sample of recognized leaders in the neuroscientific community at a significant instant in the history and evolution of the field

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Product Details

  • ISBN-13: 9780444816788
  • Publisher: Elsevier Science
  • Publication date: 8/2/1994
  • Series: Progress in Brain Research Series, #10
  • Edition description: New Edition
  • Pages: 300

Meet the Author

Floyd Bloom was the editor of Science magazine, now Brain Research.
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Table of Contents

List of Contributors
Preface
Then and now
1 Cell migrations and establishment of neuronal connections in the developing brain: a study using the quail-chick chimera system 3
2 Development of sympathetic neurons: neurotransmitter plasticity and differentiation factors 19
3 Lessons from genetic knockout mice deficient in neural recognition molecules 25
4 Quantitative analysis of neuronal gene expression 33
5 Molecular pharmacology of NMDA receptors: modulatory role of NR2 subunits 39
6 Glutamate receptors and the induction of excitotoxic neuronal death 47
7 Sodium/potassium-coupled glutamate transporters, a "new" family of eukaryotic proteins: do they have "new" physiological roles and could they be new targets for pharmacological intervention? 53
8 GABA[subscript C] receptors 61
9 The central cholinergic system during aging 67
10 Co-existence of chemical messengers in neurons 73
11 Cloning of kappa opioid receptors: functional significance and future directions 81
12 Vasoactive intestinal peptide and noradrenaline regulate energy metabolism in astrocytes: a physiological function in the control of local homeostasis within the CNS 87
13 Segmental and descending control of the synaptic effectiveness of muscle afferents 97
14 Noradrenergic control of cerebello-vestibular functions: modulation, adaptation, compensation 105
15 Chemical transmission in the brain: homeostatic regulation and its functional implications 115
16 Conservation of basic synaptic circuits that mediate GABA inhibition in the subcortical visual system 123
17 Hypothalamic magnocellular neurosecretory neurons: intrinsic membrane properties and synaptic connections 133
18 Molecular principles from neuroendocrine models: steroid control of central neurotransmission 139
19 Resolving a mystery: progress in understanding the function of adrenal steroid receptors in hippocampus
20 Neural-immune interactions 157
21 Human cortical functions revealed by magnetoencephalography 163
22 The prefrontal system: a smorgasbord 169
23 A comparison of the mechanistic relationships between development and learning in Aplysia 179
24 Synapse-activated protein synthesis as a possible mechanism of plastic neural change 189
25 Plasticity of adult central fibre tracts 195
26 Brain damage and recovery 203
27 Trophic factor therapy in the adult CNS: remodelling of injured basalo-cortical neurons 213
28 ACTH/MSH-derived peptides and peripheral nerve plasticity: neuropathies, neuroprotection and repair 223
29 Enhancement of action potential conduction following demyelination: experimental approaches to restoration of function in multiple sclerosis and spinal cord injury 233
30 Functional integrity of neural systems related to memory in Alzheimer's disease 245
31 The search for a manic depressive gene: from classical to molecular genetics 255
32 Age, sex and light: variability in the human suprachiasmatic nucleus in relation to its function 261
33 Schizophrenia: neurobiological perspectives 267
34 New solutions for neuroscience communications are still needed 275
Subject Index 283
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