New Therapies for Neonatal Respiratory Failure / Edition 1

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This book provides a comprehensive overview of respiratory physiology in the newborn, and of the mechanisms underlying respiratory failure in this age group. The authors describe in detail the techniques, both novel and well established, for effective ventilatory support. In presenting and evaluating the available treatment options, the authors consider not only clinical indications, modes of delivery and monitoring, but also complications and outcomes.

The book contains black-and-white illustrations.

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Editorial Reviews

From the Publisher
"...fills an otherwise nearly empty niche by providing an overview of this rapidly changing field, while providing a sound physiologic basis upon which to build a deeper understanding of the techniques described. Drs Boynton, Carlo, and Jobe are superbly qualified to edit such a book because they have been intimately involved in various aspects of neonatal respiratory research for many years...useful and interesting commentaries are added throughout by other noted researchers and clinicians in neonatology...most valuable to physicians and neonatal caregivers who treat infants requiring these therapies or to those who plan to do so. For these professionals, it is invaluable because it provides a review of pertinent physiology and literature in addition to providing in-depth information on the various modalities reviewed. It is a valuable teaching tool as well as a useful reference." Sherry E. Courtney, Respiratory Care

"...should be available wherever infants are being ventilated. It is an invaluable asset for pediatric residents, respiratory therapists and nursing staff...this book will permit every physician involved in critical care to re-learn basic physiological principles, and to bring themselves up to date on recent advances, some of which they are starting to incorporate into their practices," Marc Blayney, Annals RCPSC

"I found the overall presentation and discourse brief, delightful, complete with pithy yet insightful comments, and I think that this format of monograph is to be encouraged....a well-balanced, well-written summary of the present state of knowledge. The format with the commentators is particularly valuable in delineating the areas of controversy while adding a degree of leavening to the text to render the material readable." Canadian Respiratory Journal

"This peerless book has clearly achieved its objectives. It will be a most valuable guide and reference for neonatologists, pediatric pulmonologists, pediatric critical care specialists, and anesthesiologists." James W. Kendig, Bulletin of the New York Academy of Medicine

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Product Details

  • ISBN-13: 9780521431613
  • Publisher: Cambridge University Press
  • Publication date: 11/28/1994
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 357
  • Product dimensions: 6.97 (w) x 9.96 (h) x 1.06 (d)

Table of Contents

Part I. Surfactant; 1. Composition and structure of pulmonary surfactant Jeffrey A. Whitset; 2. Surfactant function and metabolism Alan H. Jobe; 3. Surfactant inactivation Machiko Ikegami; 4. Surfactant in the prevention and treatment of respiratory distress syndrome Roger F. Soll, T. Allen Merritt and Millo Hallman; 5. Lung surfactant replacement for neonatal pathology other than primary respiratory distress syndrome Jonathan M. Davis and Robert H. Notter; Part II. Mechanical Ventilation: 6. The mechanics of breathing Gregory P. Heldt; 7. Pulmonary gas exchange: basic principles and the effects of mechanical ventilation Bruce R. Boynton and Michael D. Hammond; 8. Advances in conventional mechanical ventilation Waldemar A. Carlo, Anne Greenhough and Robert L. Chatburn; 9. Patient initiated mechanical ventilation Gregory P. Heldt and Graham Bernstein; 10. Physiologic monitoring M. Douglas Cunningham; 11. Oscillatory mechanics: the pressure cost of high frequency ventilation Jose F. Venegas and Jeffrey J. Fredberg; 12. Pulmonary gas exchange during high frequency ventilation Bruce R. Boynton and Waldemar A. Carlo; 13. High frequency oscillatory ventilation and high frequency flow interruption Patricio Fernandez-Martorell and Bruce R. Boynton; 14. High frequency jet ventilation Carl H. Coghill, Waldemar A. Carlo and Richard J. Martin; 15. Negative pressure ventilation Eduardo Bancalri; 16. Techniques of oxygenation and ventilation with continuous gas flow Jesus Villar and Arthur S. Slutsky; 17. Liquid ventilation Thomas H. Shaffer, Jay S. Greenspan and Marla R. Wolfson; Part III. Extracorporeal Membrane Oxygenation; 18. Extracorporeal respiratory assist for acute respiratory failure Kyoji Tsuno and Theodor Kolobow; 19. Clinical use of ECMO Billie Lou Short; Part IV. Nitric Oxide Inhalation; 20. Physiology of nitric oxide in the perinatal lung Jesse D. Roberts and Steven H. Abman.
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