Nitric Oxide, Cell Signaling, and Gene Expression

by Santiago Lamas (Editor)

Overview

Since the nineteenth century, when engineers were using nitroglycerin to blow up rockbeds, and doctors were prescribing it to relieve angina, scientists have been exploring the incredible and often baffling behavior of nitric oxide. In the 1980s, researchers discovered that nitric oxide had the capacity to regulate vascular tone through cyclic GMP,

Product Details

ISBN-13:	9781040204511
Publisher:	CRC Press
Publication date:	11/01/2005
Series:	Oxidative Stress and Disease
Sold by:	Barnes & Noble
Format:	eBook
Pages:	456
File size:	5 MB

About the Author

Santiago Lamas

Table of Contents

Nitric Oxide Controls Cell Respiration by Reacting with Mitochondrial Complex IV. Mitochondrial Nitric Oxide Signaling in Synaptic Plasticity and Cell Death. Mitchondrial Nitric Oxide and Redox Signaling Modulation of Cell Behavior. Functions of Mitochondrial Nitric Oxide Synthase. Peroxynitrite: A Mediator of Nitric Oxide-Dependent Mitochondrial Dysfunction in Pathology. Modulation of Glucose Metabolism by Nitric Oxide in Astrocytes and Neurons. Nitric Oxide Cell Signaling Mediated by cGMP. Regulation of Cell Signaling by Protein Nitrosylation/Denitrosylation. Nitric Oxide and Caspase Activation. Signaling Effects of Peroxynitrite in Mammalian Cells. Nitric Oxide and Cell Signaling: Redox Regulation of Ras Superfamily GTPases. NO and the HIF-1 Transducing Systems. The Crosstalk between Nitric Oxide and Ceramide: Coordinate Interactions Among Signaling Pathways Regulating Cell Death, Survival, and Differentiation. Nitrosothiol Signaling and Gene Regulation in Pulmonary Pathophysiology. Nitric Oxide and Gene Expression. Nitric Oxide as a Modifier of Gene Expression. Nitric Oxide and Post-Transcriptional Control of Gene Expression. Nitric Oxide and Tumor Biology.

Editorial Reviews

… is very timely, bringing readers up to date with various facets of the work being carried out. … For an in-depth discussion of certain aspects of nitric oxide in mammalian systems, this is a very good book to read, with the excellent referencing that will allow for expanded further reading. …”
— John T Hancock, School of Biosciences, University of the West of England, U.K., in The Quartely Review of Biology, Vol. 81, December 2006

From the Publisher