NMR of Biomolecules


NMR is one of the most powerful methods for imaging of biomolecules. This book is the ultimate NMR guide for researchers in the biomedical community and gives not only background and practical tips but also a forward looking view on the future of NMR in systems biology.
Read More Show Less
... See more details below
Other sellers (Paperback)
  • All (5) from $106.69   
  • New (4) from $106.69   
  • Used (1) from $120.79   


NMR is one of the most powerful methods for imaging of biomolecules. This book is the ultimate NMR guide for researchers in the biomedical community and gives not only background and practical tips but also a forward looking view on the future of NMR in systems biology.
Read More Show Less

Product Details

  • ISBN-13: 9783527328505
  • Publisher: Wiley
  • Publication date: 4/24/2012
  • Edition number: 1
  • Pages: 650
  • Sales rank: 1,274,085
  • Product dimensions: 8.10 (w) x 11.00 (h) x 1.30 (d)

Meet the Author

Ivano Bertini is a Professor of Chemistry and Founding Director of the Magnetic Resonance Center (CERM) at the University of Florence. His main research interests include advancements in nuclear magnetic resonance spectroscopy, the expression and preparation of metalloproteins, their structural characterization, and the investigation of their interactions, with an emphasis on understanding cellular processes at the molecular level. He has authored over 600 scientific publications and several books, and is or has been on the editorial staff or advisory board of over 20 of the most authoritative journals in chemistry, biochemistry and inorganic chemistry. He is a member of the Academia Europaea and the Italian Accademia dei Lincei.

Kathleen S. McGreevy is a researcher in bioinformatics at the Magnetic Resonance Center (CERM) at the University of Florence. After obtaining a degree in Mechanical Engineering from the University of Virginia in 2002, she became involved in the support and management of research activities in the biomedical sciences before moving to her current position. She has been involved in the management of several European projects, notably the FP6-funded Coordination Action NMR-Life, from which this volume takes its inspiration.

Giacomo Parigi, degree in Physics at the University of Florence (1992) and PhD in Chemistry, is Associate Professor of General and Inorganic Chemistry at the Magnetic Resonance Center (CERM) and the Department of Chemistry of the University of Florence. His research interests are mainly oriented to the study of NMR effects related to paramagnetism for the structural and dynamic characterization of biomolecules, to the analysis of the relaxometric profiles of paramagnetic systems and biomolecules, and to nuclear and electron relaxation.

Read More Show Less

Table of Contents

Website: www.wiley-vch.de/home/nmrbiomol

NMR and its place in Mechanistic Systems Biology (Bertini, McGreevy, Parigi)
The structure of biomolecules: fundamentals
Structural features of proteins (Banci, Cantini)
Structural features of nucleic acids (Cevec, Jonker, Nozinovic, Richter, Schwalbe)
What can be learned about the structure and dynamics of biomolecules from NMR
Proteins studied by NMR (Ferella, Rosato, Turano)
Nucleic acids studied by NMR (Plavec)
Determination of protein structure and dynamics (Ferella, Rosato, Turano)
DNA (Plavec)
RNA (Stefl, Sklen?r)
Intrinsically disordered proteins (Felli, Pierattelli, Tompa)
Paramagnetic molecules (Bertini, Luchinat, Parigi)
NMR methodologies for the analysis of protein interactions (Madl, Sattler)
Metal-mediated interactions (Ciofi-Baffoni)
Protein-paramagnetic protein interactions (Keizers, Hiruma, Ubbink)
Protein-RNA interactions (Manoharan, Perez-Canadillas, Ramos)
Protein-DNA interactions (Kovacic, Boelens)
High-throughput screening and fragment-based design: general considerations for lead discovery and optimization (Pellecchia)
Ligand-observed NMR in fragment-based approaches (Sledz, Abell, Ciulli)
Interactions of metallodrugs with DNA (Sadler)
RNA as a drug target (Ferner, Duchardt-Ferner, Rinnenthal, Buck, Wöhnert, Schwalbe)
Fluorine NMR spectroscopy for biochemical screening in drug discovery (Dalvit)
NMR of peptides (Beck, Frank, Kessler)
Biomolecular solid state NMR - basics (Barbet-Massin, Pintacuda)
Protein dynamics in the solid-state (Lewandowski, Emsley)
Microcrystalline proteins -
An ideal benchmark for methodology development (Franks, van Rossum, Bardiaux, Ravera, Parigi, Luchinat, Oschkinat)
Structural studies of protein fibrils by solid-state NMR (Böckmann, Meier)
Membrane proteins (Cukkemane, Renault, Baldus)
Dynamic nuclear polarization (Prisner)
13C direct detection NMR (Felli, Pierattelli)
Speeding up multidimensional NMR data acquisition (Brutscher, Marion, Frydman)
Metabolomics (Tenori)
In cell NMR spectroscopy (Burz, Cowburn, Dutta, Shekhtman)
Structural investigation of cell-free expressed membrane proteins (Sobhanifar, Reckel, Löhr, Bernhard, Dötsch)
Grid computing (Rosato)
Protein-protein docking with HADDOCK (Schmitz, Melquiond, de Vries, Karaca, van Dijk, Kastritis, Bonvin)
Automated protein structure determination methods (Guerry, Herrmann)
NMR structure determination of protein-ligand complexes (Schieborr, Sreeramulu, Schwalbe)
SAXS/SANS as methods complementary to NMR (Petoukhov, Svergun)

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)