Nobel Lectures in Physiology or Medicine 1981-1990

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Product Details

  • ISBN-13: 9789810207939
  • Publisher: World Scientific Publishing Company, Incorporated
  • Publication date: 5/28/1993
  • Pages: 596
  • Product dimensions: 6.57 (w) x 9.77 (h) x 1.31 (d)

Table of Contents

Foreword
Preface
1981 Roger W. Sperry, David H. Hubel and Torsten N. Wiesel 1
Presentation Speech 3
Biography of Roger W. Sperry 7
Some Effects of Disconnecting the Cerebral Hemispheres 9
Biography of David H. Hubel 21
Evolution of Ideas on the Primary Visual Cortex, 1955-1978: A Biased Historical Account 24
Biography of Torsten N. Wiesel 59
The Postnatal Development of the Visual Cortex and the Influence of Environment 61
1982 Sune K. Bergstrom, Bengt I. Samuelsson and Sir John R. Vane 85
Presentation Speech 87
Biography of Sune K. Bergstrom 91
The Prostaglandins: From the Laboratory to the Clinic 93
Biography of Bengt I. Samuelsson 115
From Studies of Biochemical Mechanisms to Novel Biological Mediators: Prostaglandin Endoperoxides, Thromboxanes and Leukotrienes 117
Biography of John R. Vane 141
Adventures and Excursions in Bioassay: The Stepping Stones to Prostacyclin 145
1983 Barbara McClintock 171
Presentation Speech 173
Biography of Barbara McClintock 177
The Significance of Responses of the Genome to Challenge 180
1984 Niels K. Jerne, Georges J. F. Kohler and Cesar Milstein 201
Presentation Speech 203
Biography of Niels K. Jerne 209
The Generative Grammar of the Immune System 211
Biography of Georges J. F. Kohler 227
Derivation and Diversification of Monoclonal Antibodies 228
Biography of Cesar Milstein 245
From the Structure of Antibodies to the Diversification of the Immune Response 248
1985 Michael S. Brown, Joseph L. Goldstein 271
Presentation Speech 273
Biography of Michael S. Brown 277
Biography of Joseph L. Goldstein 281
Receptor-Mediated Pathway for Cholesterol Homeostasis 284
1986 Stanley Cohen, Rita Levi-Montalcini 325
Presentation Speech 327
Biography of Stanley Cohen 331
Epidermal Growth Factor 333
Biography of Rita Levi-Montalcini 347
The Nerve Growth Factor: Thirty-Five Years Later 349
1987 Susumu Tonegawa 371
Presentation Speech 373
Biography of Susumu Tonegawa 377
Somatic Generation of Immune Diversity 381
1988 Sir James W. Black, Gertrude B. Elion and George H. Hitchings 407
Presentation Speech 409
Biography of James W. Black 413
Drugs from Emasculated Hormones: The Principles of Syntopic Antagonism 418
Biography of Gertrude B. Elion 443
The Purine Path to Chemotherapy 447
Biography of George H. Hitchings, Jr. 471
Selective Inhibitors of Dihydrofolate Reductase 476
1989 Harold E. Varmus, J. Michael Bishop 495
Presentation Speech 497
Biography of Harold E. Varmus 501
Retroviruses and Oncogenes I 504
Biography of J. Michael Bishop 525
Retroviruses and Oncogenes II 530
1990 Joseph E. Murray, E. Donnall Thomas 549
Presentation Speech 551
Biography of Joseph E. Murray 555
The First Successful Organ Transplants in Man 558
Biography of E. Donnall Thomas 573
Bone Marrow Transplantation - Past, Present and Future 576
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