Normal Testicular Descent and the Aetiology of Cryptorchidism / Edition 1

by John M. Hutson, Masaru Terada, Baiyun Zhou, Martyn P.L. Williams

Overview

This review describes recent research into the cause of testicular descent and discusses two controversial theories on the mechanism. New animal models of cryptorchidism are described which shed light on the possible aetiology. A brief summary is given of current management, highlighting the controversies of timing of surgery, use of hormone therapy and congenital versus 'acquired' undescended testes. New information about germ cell development in the postnatal testis is changing the way we view treatment and the ultimate prognosis.

Product Details

ISBN-13:	9783540602835
Publisher:	Springer Berlin Heidelberg
Publication date:	12/20/1995
Series:	Advances in Anatomy, Embryology and Cell Biology , #132
Edition description:	Softcover reprint of the original 1st ed. 1996
Pages:	56
Product dimensions:	6.10(w) x 9.25(h) x 0.10(d)

About the Author

Huston, John M., MD (Royal Children's Hospital, Victoria); Terada, Masaru, MD (Shinshu Univ); Zhou, Baiyum, MD (Royal Children's Hospital, Victoria); Williams, Martyn P.L., MD

Table of Contents

1 Introduction.- 2 Normal Testicular Descent.- 2.1 Two-Stage Hypothesis.- 2.2 Role of Müllerian Inhibiting Substance/Anti-Müllerian Hormone.- 2.3 Genitofemoral Nerve Hypothesis.- 2.4 Role of Calcitonin Gene-Related Peptide.- 2.5 Hypothesis to Explain Normal Testicular Descent.- 3 Cryptorchidism.- 3.1 Animal Models.- 3.2 Hypotheses of Aetiology.- 3.3 Recognizable Causes of Cryptorchidism.- 3.4 Congenital vs Acquired Cryptorchidism.- 3.5 Effects of Cryptorchidism.- 4 Management of Cryptorchidism.- 4.1 Rationale for Treatment and Its Timing.- 4.2 Surgical Treatment.- 4.3 Hormonal Treatment.- 4.4 Possible New Approaches to Treatment.- 5 Conclusions.- 6 References.- 7 Subject Index.

Editorial Reviews

Reviewer: Robert M Arensman, MD (University of Illinois at Chicago College of Medicine)
Description: This monograph is number 132 in the series entitled Advances in Anatomy, Embryology, and Cell Biology. This 56-page text deals exclusively with testicular descent and cryptorchidism.
Purpose: The four authors are all previously published on these subjects and indicate that the purpose of the present publication is to describe "the recent results of studies on normal descent, with emphasis on our studies of the different stages of descent."
Audience: Any scientific person with interest in this area will find this a comprehensive review, although pediatric surgeons, urologists, neonatologists, embryologists, and anatomists will constitute the primary audience. Medical students and residents in the appropriate specialties will find it an invaluable resource monograph, although rather advanced and detailed as a primary source.
Features: The book is heavily illustrated with pictures, drawings, graphs, scanning electron micrographs, and microscopic photographs. These add nicely to easy reading and comprehension of the text. The references are extensive and current. They are quite useful for further study and reading in this highly specific area.
Assessment: This is a nicely written and illustrated monograph dealing only with the current knowledge and experimental work on testicular descent and the etiology of cryptorchidism. It will serve as an excellent review of the most current information on this subject and includes substantial reference sources for further study.

Doody's Review Service

4 Stars! from Doody

This monograph is number 132 in the series entitled Advances in Anatomy, Embryology, and Cell Biology. This 56-page text deals exclusively with testicular descent and cryptorchidism. The four authors are all previously published on these subjects and indicate that the purpose of the present publication is to describe the recent results of studies on normal descent, with emphasis on our studies of the different stages of descent. Any scientific person with interest in this area will find this a comprehensive review, although pediatric surgeons, urologists, neonatologists, embryologists, and anatomists will constitute the primary audience. Medical students and residents in the appropriate specialties will find it an invaluable resource monograph, although rather advanced and detailed as a primary source. The book is heavily illustrated with pictures, drawings, graphs, scanning electron micrographs, and microscopic photographs. These add nicely to easy reading and comprehension of the text. The references are extensive and current. They are quite useful for further study and reading in this highly specific area. This is a nicely written and illustrated monograph dealing only with the current knowledge and experimental work on testicular descent and the etiology of cryptorchidism. It will serve as an excellent review of the most current information on this subject and includes substantial reference sources for further study.

Robert M. Arensman