Novel Approaches in Biosensors and Rapid Diagnostic Assays / Edition 1

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Overview

In the medical, food, and environmental fields there is a continuous demand for inexpensive and sensitive analytical devices that are reliable, rapid, capable of high-throughput screening, and have low cost per test unit. Small and portable biosensor devices are designed to fulfill most of these requirements, and can be used in laboratory and on-site field testing.
This volume discusses major issues in optical, acoustic and electrochemical-based biosensors, biochips, sensing recognition elements, and biosensors for medical and environmental applications. The papers presented at the conference represent basic and applied research studies in the fields of diagnostic assays and biosensor development. Novel technologies, such as arrays of sensors using high-density fiber optics to sense labeled or unlabeled oligonucleotides, and patterned arrays of recognition elements, demonstrated the capability of biosensors to analyze multiple analytes.

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Product Details

  • ISBN-13: 9780306464447
  • Publisher: Springer US
  • Publication date: 10/10/2001
  • Edition description: 2001
  • Edition number: 1
  • Pages: 323
  • Product dimensions: 0.81 (w) x 7.00 (h) x 10.00 (d)

Table of Contents

1 Analyzing Unamplified Gene Sequences with High Density Optical Fiber Arrays 1
2 Array Biosensor for Simultaneous Detection of Multiple Analytes 7
3 Acoustic Wave Study of Interfacially-Bound Proteins, Nucleic Acids and Blood Platelets 17
4 High Frequency Acoustic STW Biosensor 33
5 Ultrasensitive and Specific Electronic Transduction of DNA Sensing Processes 47
6 Enzyme-Amplified Amperometric Detection of Hybridization and of a Single Base Pair Mutation in an 18 Base Oligonucleotide on a 7[mu]m Diameter Microelectrode 79
7 Development and Application of Bioelectrochemical Sensors for On-Site Monitoring 101
8 Sol-Gel Derived Composite Ceramic Carbon Biosensors 111
9 Holographic Biosensors 127
10 Waveguide Fluorosensor for the Detection of Ligand-Receptor Interactions: The 5-HT[subscript 3] Serotonin Receptor 135
11 Importance of Biochips in the Study of Neuronal Nicotinic Acetylcholine Receptors: Biochips and Nicotinic Receptors 147
12 Improving DNA-Chip Technology: Chemical Aspects 165
13 The Application of Biorecognition 173
14 The Use of Imprinted Polymers as Recognition Elements in Biosensors and Binding Assays 193
15 Molecular Imprinting and Chemical Sensing: Synthetic Antibodies 211
16 Electropolymerizable Bipyrrole-Biotin: A New Derivative for the Immobilization of Ligands onto Electrode Surfaces 225
17 New Approaches to Rapid Diagnostics Using Bichromic Polymers and Organic Thin Films 235
18 Recent Uses of Microspheres in Diagnostic Tests and Assays 245
19 Luminescence Oxygen Channeling Assay (LOCI): A Highly Sensitive and Versatile Homogeneous Assay Method 265
20 Direct and Continuous Measurements of Oxygen Partial Pressure Using a Tissue-Inserted Optical Oxygen Microsensor: During Photodynamic Therapy 273
21 Glucose Monitoring by Reverse Iontophoresis 285
22 Rapid Methods of Microbiological Analysis: An Update 295
23 Revolutionary Technologies for Bio Detection 313
Index 319
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