Nutrient-Drug Interactions

Hardcover (Print)
Buy New
Buy New from BN.com
$107.79
Used and New from Other Sellers
Used and New from Other Sellers
from $40.74
Usually ships in 1-2 business days
(Save 68%)
Other sellers (Hardcover)
  • All (6) from $40.74   
  • New (3) from $117.05   
  • Used (3) from $40.74   

Overview

Current research has given us a more complete understanding of how the chemicals in foods and herbs interact with natural and synthetic drugs. In some cases a single food or supplement can profoundly increase or decrease the toxicity and/or efficacy of a single drug. Although it is standard practice to examine the effects of food consumption on the absorption and pharmacokinetics of new drugs, the issue has become greater than "should this medicine be taken with or without food."

Nutrient-Drug Interactions focuses on food, herbals, and their chemical constituents as contributors to human health through control of metabolism, primarily as they relate to chronic disease development and treatment. The book's organization highlights the ailment being treated or prevented and the targets of therapy. Each chapter provides a comprehensive examination of the macronutrient, micronutrient, and phytochemical impact on drug action and includes advice on modification or supplementation in those cases where diet is a factor. The chapters focus on the molecular mechanism by which a food or chemical is thought to modify disease process and drug behavior. The book describes the roles of genetic variation and polymorphism in determining nutrient/drug responses, how they might be "profiled" to identify those likely to demonstrate specific interactions, and who would benefit from adjuvant or complementary therapies.

The book explores how what is consumed affects response, whether on a population or individual level, to the pharmacologic agents that are the mainstay of chronic disease treatment/prevention around the world.

Read More Show Less

Editorial Reviews

Doody's Review Service
Reviewer: Paul R Hutson, Pharm.D., M.S.(University of Wisconsin)
Description: This book provides an up-to-date summary of disease-based pathobiology and the mechanism of drug classes currently used in each disease. In this context, the chapters then introduce nutrients or dietary supplements that may enhance or attenuate the effect of the drugs.
Purpose: The editor's purpose is to present evidence-based summaries of the effects of food and herbals upon commonly used drugs. This is a timely and useful objective, as there is a burgeoning amount of new information on disease processes, pharmacologic mechanisms, and in vitro and clinical effects of dietary supplements. This book is helpful in providing a mechanistic understanding of how drug-nutrient interactions might be expected, or have been proven to occur. Different chapter authors provide varying degrees of interpretation of the magnitude and clinical impact of these interactions.
Audience: The book is clearly written and provides sufficient background to allow students and practitioners alike to understand the mechanisms of the interactions. The limited detail of clinical study results or of their clinical implications limits the utility of the book to practicing physicians, pharmacists, and dieticians. However, it does provide extremely useful distillations by experts in their fields that will be appreciated by those seeking a mechanistic understanding of drug-supplement interactions that will guide their clinical decisions.
Features: The topics covered in this book reflect the diseases for which the public most commonly uses dietary supplements. These include cancer treatment and prevention, dyslipidemias, and neurodegenerative or psychiatric disorders. In addition, useful chapters cover interactions with anesthetic agents, and gene expression effects that may have clinical relevance. There are limited figures, and none are in color. Additional figures to illustrate biochemical pathways would be helpful, as would tables to summarize the magnitude of any effects noted in pivotal clinical trials of the supplements considered.
Assessment: This book is well written and provides a mechanistic understanding of the known or likely effects of components found in common dietary supplements as they relate to the functioning of major drug classes. While the scope of the book excludes consideration of some dietary supplements such as CoQ10 or glucosamine, the book does provide an extremely helpful framework by which the effects and interactions of drugs and nutrients can be understood. In this regard, it is more helpful in providing a mechanistic understanding than other books and references such as the Natural Medicines Comprehensive Database, 8th edition (Pharmacists Letter, 2005), or Drug Facts and Comparisons 2006, 60th edition (Wolters Kluwer Health, 2005).
Read More Show Less

Product Details

Table of Contents

Diabetes, Obesity and Metabolic Syndrome, A.J. Scheen

Hypolipidemic Therapy: Drugs, Diet, and Interactive Effects, A. Loktionov

Phytochemicals, Xenobiotic Metabolism, and Carcinogenesis, J.B. Kirkland

Nutrient and Phytochemical Modulation of Cancer Treatment, K.A. Meckling

Role of Nutritional Antioxidants in the Prevention and Treatment of Neurodegenerative Disorders, E. Esposito

Nutrients and Herbals in the Pharmacotherapy of Unipolar/Major Depression, M. Chronowic

Supplements and Anesthesiology, A.D. Kaye, A. Baluch, and J.M. Hoover

Nutrient and Drug Responsive Polymorphic Genes as Nutrigenomic Tools for Prevention of Cardiovascular Disease and Cancer, K. Wood and M. Bakovic

Nutrigenomics and Pharmacogenomics of Human Cancer: On the Road from Nutrigenetics and Pharmacogenetics, A. Loktionov
Index

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)